Tnfrsf11b (NM_008764) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR206291L3V
- LentiORF®
Lenti ORF particles, Tnfrsf11b (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b), 200ul, >10^7 TU/mL
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CNY 7,410.00
货期*
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Specifications
Product Data | |
Product Name | Tnfrsf11b (NM_008764) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | OCIF; Opg; TR1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_008764 |
ORF Size | 1206 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR206291).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008764.3, NP_032790.3 |
RefSeq Size | 2818 bp |
RefSeq ORF | 1206 bp |
Locus ID | 18383 |
Gene Summary | Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.[UniProtKB/Swiss-Prot Function] |
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