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Tnfrsf11b (NM_008764) Mouse Untagged Clone
CAT＃: MC204712
Tnfrsf11b (untagged) - Mouse tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b), (10ug)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | OCIF; Opg; TR1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC049782
GACGCACCTAGCACTGACCCAGCGGCTGCCTCCTGAGGTTTCCCGAGGACCACAATGAACAAGTGGCTGT GCTGCGCACTCCTGGTGCTCCTGGACATCATTGAATGGACAACCCAGGAAACCCTTCCTCCAAAGTACTT GCATTATGACCCAGAAACTGGTCATCAGCTCCTGTGTGACAAATGTGCTCCTGGCACCTACCTAAAACAG CACTGCACAGTGAGGAGGAAGACATTGTGTGTCCCTTGCCCTGACCACTCTTATACGGACAGCTGGCACA CCAGTGATGAGTGTGTGTATTGCAGCCCAGTGTGCAAGGAACTGCAGTCCGTGAAGCAGGAGTGCAACCG CACCCACAACCGAGTGTGTGAGTGTGAGGAAGGGCGTTACCTGGAGATCGAATTCTGCTTGAAGCACCGG AGCTGTCCCCCGGGCTCCGGCGTGGTGCAAGCTGGAACCCCAGAGCAAAACACAGTTTGCAAAAAATGTC CAGATGGGTTCTTCTCAGGTGAGACTTCATCGAAAGCACCCTGTAGAAAACACACGAACTGCAGCACATT TGGCCTCCTGCTAATTCAGAAAGGAAATGCAACACATGACAACGTGTGTTCCGGAAACAGAGAAGCCACG CAAAAGTGTGGAATAGATGTCACCCTGTGTGAAGAGGCCTTCTTCAGGTTTGCTGTTCCTACCAAGATTA TACCAAATTGGCTGAGTGTTTTGGTGGACAGTTTGCCTGGGACCAAAGTGAATGCCGAGAGTGTAGAGAG GATAAAACGGAGACACAGCTCACAAGAGCAAACCTTCCAGCTGCTGAAGCTGTGGAAACATCAAAACAGA GACCAGGAAATGGTGAAGAAGATCATCCAAGACATTGACCTCTGTGAAAGCAGCGTGCAGCGGCATCTCG GCCACGCGAACCTCACCACAGAGCAGCTTCGTGCCTTGATGGAGAGCCTGCCTGGGAAGAAGATCAGCCC AGAAGAAATTGAGAGAACGAGAAAGACCTGCAAATCGAGCGAGCAGCTCCTGAAGCTACTCAGTTTATGG AGGATCAAAAATGGTGACCAAGACACCTTGAAGGGCCTGATGTATGCCCTCAAGCACTTGAAAACATCCC ACTTTCCCAAAACTGTCACCCACAGTCTGAGGAAGACCATGAGGTTCCTGCACAGCTTCACAATGTACAG ACTGTATCAGAAGCTCTTTTTAGAAATGATAGGGAATCAGGTTCAATCTGTGAAAATAAGCTGCTTATAA CTAGGAATGGTCACTGGGCTGTTTCTTCAGGACGGGCCAAAACTGACTGAGGAGAAGAAGACTGTTTCTC AAGCACTTGAAACGGCCCAGTGATTCCTTTCTCATCAGTCGGGGGGAATGAAGACCGCCCCCACCCCCAA CACACACACTGGGGACTCTGAGTCCGGAGAGGGAGGAAGGCTATTTTATAATTGTATAAAACCAGGTGTA TACCCAGAAAGCCAAGCATGCTGAGTGAGAACAGAGGGTAGCTTTTTTTATAACCTCAAACATACGTCCC TTCCTTCCTCTCCTCACAGCTGAGCAATCAGATGGCTTCTACTATTTTATGTGTCACCCCTAGATGAAGG TCTGTTTCCTTCTGCATCTGATAGTCTATGACGTTCTGTTTATAATGCTTATCAGAGCCTCATCACCTTT GTAGGTTGCTAGGCAAGCTTGACTGTTAGCTATTTTTCCCTCTAAAGATTTGATTTGAGTTGCAGACTTA GCTAGACAGGCAGGGGTGGGTTGTGGTAGTTTATTTAACAGATTGCCACCAAGAGCCCAGTGTTTCTTGT TCCTCTGTAGTTGGATCTAAGCTGACTCAAAGTACTTTTAGTTTGAAAAATAATCAACTAATTTTATTTC TTACATTAACAATGGCTGGCTTGGTTTCATAGCACCAGAAGAAACTACTATATGGAGAAAGAATTGATAT CTCCTCCAATATTCAACAAATCCCCAACAGTTTATCCAGCTGTCATGTCTGGTTCAGTATCTACAGACTG TGTGTCCTCTCATTACCACATGTAGTAATTCAACTGGAAATAATAGTAATAGTAGTAATAGAAATCAAAT CTAGACTCCATTGGATCTCTTTGAATATGGTAATATCAATGTAAAAGTCTTTGAGATTTCAGTTGTATTA AAGGCTTTTATTAAAAAGCTGATGTTCTTCTGTAAAAGTTACTAATATATCTGTAAGACTATTACAGTAT TTCTATTTATATTCATGCAGATATGTTTTGTACATATTATAAACCTAGAGAGAAATGTTGTAGGACTTAA TTTTAGAAAGAAAAAATATTCTGTTTACTATTGAGACAAATAAAAGAGATAAAATATATTTTTAATAGAA ACTTTGTAGTGTTTTCCAATAGGTACTGTCAGTTTTCCAGTGTGGAATGTTTTTATAATATTATTTTATC TGTATAAGATGTAATATCATTTTATAGAAAAATACATTATGTATTCAGTTGTTTAATGTCAGAAAGTGTA TGAACTATAAATTATCTGAATATTAGATGCTCTGAGAAATTGAATGTACCTTATTTAAAGATTTTTATGA TCATACTATATAAATAGCATCATTAAAGTTTTCAAATTATTTTTAAAAAAAAAAAAAAAAAAAAAAAAAA AAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_008764 |
| Insert Size | 1206 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC049782, AAH49782 |
| RefSeq Size | 2663 bp |
| RefSeq ORF | 1206 bp |
| Locus ID | 18383 |
| UniProt ID | O08712 |
| Gene Summary | Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG206291 | Tnfrsf11b (tGFP-tagged) - Mouse tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) |
CNY 3,710.00 |
|
| MR206291 | Tnfrsf11b (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) |
CNY 3,656.00 |
|
| MR206291L3 | Lenti ORF clone of Tnfrsf11b (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) |
CNY 6,056.00 |
|
| MR206291L4 | Lenti ORF clone of Tnfrsf11b (mGFP-tagged) - Mouse tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) |
CNY 6,056.00 |
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