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Atg4b (NM_174874) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206129L4V
- LentiORF®
-
Lenti ORF particles, Atg4b (GFP-tagged) - Mouse autophagy-related 4B (yeast) (Atg4b), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Atg4b (NM_174874) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2510009N07Rik; Apg4b; Atg4bl; Autl1; AW048066 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_174874 |
| ORF Size | 1179 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206129).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_174874.1, NP_777363.1 |
| RefSeq Size | 2965 bp |
| RefSeq ORF | 1182 bp |
| Locus ID | 66615 |
| Gene Summary | Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms (By similarity).[UniProtKB/Swiss-Prot Function] |
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