United States
Germany
Japan
United Kingdom
China
Rsad2 (NM_021384) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR205564L4V
- LentiORF®
-
Lenti ORF particles, Rsad2 (GFP-tagged) - Mouse radical S-adenosyl methionine domain containing 2 (Rsad2), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,360.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Rsad2 (NM_021384) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2510004L01Rik; cig5; Vig1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_021384 |
| ORF Size | 1089 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR205564).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_021384.2, NP_067359.2 |
| RefSeq Size | 3785 bp |
| RefSeq ORF | 1089 bp |
| Locus ID | 58185 |
| Gene Summary | Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphosphate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
