CD101 (NM_001256111) Human Untagged Clone
CAT#: SC337721
CD101 (untagged) - Human CD101 molecule (CD101), transcript variant 4
CNY 9,220.00
货期*
5周
规格
Product images
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经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | EWI-101; IGSF2; V7 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>NCBI ORF sequence for NM_001256111, the custom clone sequence may differ by one or more nucleotides
ATGGCAGGCATCTCATATGTGGCATCTTTCTTTCTCCTTCTGACTAAGCTCAGCATTGGCCAGAGAGAAG TAACAGTTCAGAAAGGACCACTGTTTAGAGCTGAAGGTTACCCAGTCAGCATTGGCTGCAATGTAACTGG CCACCAGGGACCTTCTGAGCAGCATTTCCAGTGGTCTGTTTACCTGCCGACAAACCCGACCCAGGAAGTC CAGATCATTAGCACCAAGGATGCTGCCTTCTCTTACGCAGTATATACGCAGCGGGTGCGAAGCGGAGACG TCTACGTGGAGAGGGTCCAGGGCAACTCAGTCTTGTTGCACATCTCAAAACTCCAGATGAAGGATGCTGG CGAGTATGAGTGTCACACACCAAACACTGATGAGAAATACTATGGAAGTTACAGTGCAAAGACTAATCTA ATTGATTTTATATTGGTCCCTGGGCCCTTGTATACAGAGCGGTTTGCAGCCAGTGACGTACAGCTCAACA AACTGGGACCCACTACATTCAGGCTGTCCATAGAGAGGCTCCAGTCCTCAGATCAGGGTCAGCTGTTCTG TGAGGCAACGGAATGGATTCAGGATCCAGATGAAACTTGGATGTTCATCACCAAAAAGCAGACCGATCAA ACCACTCTGAGGATCCAGCCAGCAGTGAAAGATTTTCAAGTCAACATTACAGCTGACAGCTTGTTTGCTG AAGGGAAACCCTTAGAACTGGTTTGCCTGGTTGTAAGCAGTGGCCGTGACCCACAGCTTCAAGGCATTTG GTTCTTCAATGGGACTGAAATTGCTCACATTGATGCTGGTGGAGTCCTGGGCCTGAAGAATGACTACAAA GAGAGAGCAAGTCAAGGAGAGCTCCAGGTTTCAAAGTTAGGCCCCAAGGCTTTCTCTCTCAAGATCTTCT CTCTGGGCCCAGAGGATGAAGGCGCCTACAGATGTGTGGTAGCAGAGGTCATGAAAACACGCACAGGTTC CTGGCAGGTGCTTCAGAGAAAGCAGTCACCAGACAGCCACGTGCACCTGAGGAAGCCAGCAGCAAGAAGT GTGGTCATGTCTACCAAGAACAAGCAGCAAGTTGTGTGGGAAGGAGAGACACTCGCCTTTCTCTGTAAGG CTGGTGGAGCTGAAAGTCCCCTGTCTGTGAGCTGGTGGCACATCCCACGGGACCAGACACAGCCCGAGTT TGTGGCTGGCATGGGGCAGGATGGCATTGTGCAGCTGGGTGCCTCCTATGGGGTACCCAGTTACCATGGC AACACAAGGCTGGAGAAAATGGACTGGGCCACCTTCCAGCTGGAGATCACCTTCACTGCCATCACAGACA GTGGCACATATGAGTGCAGAGTATCTGAGAAGTCTCGGAACCAGGCCAGAGATCTGAGCTGGACTCAGAA GATTTCAGTTACTGTAAAGTCTCTGGAGTCAAGTTTACAAGTTAGTCTGATGAGCCGTCAGCCGCAAGTG ATGTTAACCAACACCTTTGACCTGTCCTGTGTCGTGAGGGCCGGTTACTCTGACCTCAAGGTGCCACTCA CTGTGACGTGGCAGTTCCAGCCAGCTAGCTCTCACATCTTCCACCAGCTTATTCGAATCACCCACAATGG CACTATTGAATGGGGGAATTTCCTATCCCGGTTCCAAAAGAAGACGAAAGTGTCGCAGTCTTTATTTCGT TCACAACTCCTAGTCCATGATGCCACTGAGGAAGAGACAGGAGTGTATCAGTGTGAAGTAGAAGTTTATG ACAGAAATTCCCTATACAACAACCGCCCCCCGAGGGCTTCTGCCATCTCTCACCCACTGAGGATAGCCGT CACTTTACCAGAGAGCAAGCTAAAAGTGAATTCAAGGAGTCAAGTCCAAGAGCTCTCCATCAACTCCAAC ACTGATATAGAATGTAGCATCTTGTCCCGGTCCAATGGAAACCTTCAGTTAGCCATTATTTGGTATTTTT CTCCTGTTTCCACTAATGCCTCTTGGCTAAAGATCCTGGAGATGGACCAAACCAATGTTATAAAAACTGG GGATGAGTTTCACACCCCACAGAGAAAACAAAAATTTCATACTGAGAAGGTTTCCCAAGACTTATTTCAG CTGCACATTCTGAATGTGGAAGACAGCGATCGGGGCAAATATCACTGTGCTGTGGAGGAATGGCTCCTGT CTACAAATGGCACTTGGCACAAGCTTGGAGAAAAGAAGTCAGGACTAACAGAATTGAAACTCAAGCCCAC AGGAAGTAAGGTACGTGTCTCCAAAGTGTACTGGACCGAAAATGTGACTGAGCACAGAGAAGTGGCCATC CGCTGCAGCCTGGAGAGTGTAGGCAGCTCAGCCACTCTGTACTCTGTGATGTGGTACTGGAACAGAGAAA ACTCTGGAAGTAAATTGCTGGTGCACTTGCAACATGATGGCTTGCTGGAGTATGGGGAAGAGGGGCTCAG GAGGCACCTGCACTGTTACCGTTCATCCTCTACAGACTTTGTCCTGAAGCTTCATCAGGTGGAGATGGAG GATGCAGGAATGTACTGGTGTAGGGTGGCAGAGTGGCAGCTCCATGGACACCCAAGCAAGTGGATTAATC AAGCATCCGATGAGTCACAGCGGATGGTGCTCACGGTGCTGCCTTCAGAGCCCACGCTTCCTTCCAGGAT CTGCTCCTCGGCCCCTTTACTCTATTTCCTGTTCATCTGTCCCTTCGTCCTGCTCCTCCTTCTGCTCATC TCCCTCCTCTGCTTATACTGGAAGGCCAGGAAGTTGTCAACACTGCGTTCCAACACACGGAAAGAAAAAG CTCTCTGGGTGGACTTGAAAGAGGCTGGAGGTGTGACCACAAATAGGAGGGAAGACGAGGAGGAAGATGA AGGCAACTGA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001256111 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001256111.2, NP_001243040.1 |
RefSeq Size | 3334 bp |
RefSeq ORF | 2880 bp |
Locus ID | 9398 |
Protein Families | Transmembrane |
Gene Summary | Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 5' coding region, and also an alternate splice site in the 3' UTR, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. |
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