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CD101 (NM_001256111) Human Tagged ORF Clone
CAT＃: RG239827
- TrueORF®
CD101 (tGFP-tagged) - Human CD101 molecule (CD101), transcript variant 4
ORF Plasmid: DDK
"NM_001256111" in other vectors (2)
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CNY 7,510.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | EWI-101; IGSF2; V7 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG239827 representing NM_001256111.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCAGGCATCTCATATGTGGCATCTTTCTTTCTCCTTCTGACTAAGCTCAGCATTGGCCAGAGAGAA GTAACAGTTCAGAAAGGACCACTGTTTAGAGCTGAAGGTTACCCAGTCAGCATTGGCTGCAATGTAACT GGCCACCAGGGACCTTCTGAGCAGCATTTCCAGTGGTCTGTTTACCTGCCGACAAACCCGACCCAGGAA GTCCAGATCATTAGCACCAAGGATGCTGCCTTCTCTTACGCAGTATATACGCAGCGGGTGCGAAGCGGA GACGTCTACGTGGAGAGGGTCCAGGGCAACTCAGTCTTGTTGCACATCTCAAAACTCCAGATGAAGGAT GCTGGCGAGTATGAGTGTCACACACCAAACACTGATGAGAAATACTATGGAAGTTACAGTGCAAAGACT AATCTAATTGATTTTATATTGGTCCCTGGGCCCTTGTATACAGAGCGGTTTGCAGCCAGTGACGTACAG CTCAACAAACTGGGACCCACTACATTCAGGCTGTCCATAGAGAGGCTCCAGTCCTCAGATCAGGGTCAG CTGTTCTGTGAGGCAACGGAATGGATTCAGGATCCAGATGAAACTTGGATGTTCATCACCAAAAAGCAG ACCGATCAAACCACTCTGAGGATCCAGCCAGCAGTGAAAGATTTTCAAGTCAACATTACAGCTGACAGC TTGTTTGCTGAAGGGAAACCCTTAGAACTGGTTTGCCTGGTTGTAAGCAGTGGCCGTGACCCACAGCTT CAAGGCATTTGGTTCTTCAATGGGACTGAAATTGCTCACATTGATGCTGGTGGAGTCCTGGGCCTGAAG AATGACTACAAAGAGAGAGCAAGTCAAGGAGAGCTCCAGGTTTCAAAGTTAGGCCCCAAGGCTTTCTCT CTCAAGATCTTCTCTCTGGGCCCAGAGGATGAAGGCGCCTACAGATGTGTGGTAGCAGAGGTCATGAAA ACACGCACAGGTTCCTGGCAGGTGCTTCAGAGAAAGCAGTCACCAGACAGCCACGTGCACCTGAGGAAG CCAGCAGCAAGAAGTGTGGTCATGTCTACCAAGAACAAGCAGCAAGTTGTGTGGGAAGGAGAGACACTC GCCTTTCTCTGTAAGGCTGGTGGAGCTGAAAGTCCCCTGTCTGTGAGCTGGTGGCACATCCCACGGGAC CAGACACAGCCCGAGTTTGTGGCTGGCATGGGGCAGGATGGCATTGTGCAGCTGGGTGCCTCCTATGGG GTACCCAGTTACCATGGCAACACAAGGCTGGAGAAAATGGACTGGGCCACCTTCCAGCTGGAGATCACC TTCACTGCCATCACAGACAGTGGCACATATGAGTGCAGAGTATCTGAGAAGTCTCGGAACCAGGCCAGA GATCTGAGCTGGACTCAGAAGATTTCAGTTACTGTAAAGTCTCTGGAGTCAAGTTTACAAGTTAGTCTG ATGAGCCGTCAGCCGCAAGTGATGTTAACCAACACCTTTGACCTGTCCTGTGTCGTGAGGGCCGGTTAC TCTGACCTCAAGGTGCCACTCACTGTGACGTGGCAGTTCCAGCCAGCTAGCTCTCACATCTTCCACCAG CTTATTCGAATCACCCACAATGGCACTATTGAATGGGGGAATTTCCTATCCCGGTTCCAAAAGAAGACG AAAGTGTCGCAGTCTTTATTTCGTTCACAACTCCTAGTCCATGATGCCACTGAGGAAGAGACAGGAGTG TATCAGTGTGAAGTAGAAGTTTATGACAGAAATTCCCTATACAACAACCGCCCCCCGAGGGCTTCTGCC ATCTCTCACCCACTGAGGATAGCCGTCACTTTACCAGAGAGCAAGCTAAAAGTGAATTCAAGGAGTCAA GTCCAAGAGCTCTCCATCAACTCCAACACTGATATAGAATGTAGCATCTTGTCCCGGTCCAATGGAAAC CTTCAGTTAGCCATTATTTGGTATTTTTCTCCTGTTTCCACTAATGCCTCTTGGCTAAAGATCCTGGAG ATGGACCAAACCAATGTTATAAAAACTGGGGATGAGTTTCACACCCCACAGAGAAAACAAAAATTTCAT ACTGAGAAGGTTTCCCAAGACTTATTTCAGCTGCACATTCTGAATGTGGAAGACAGCGATCGGGGCAAA TATCACTGTGCTGTGGAGGAATGGCTCCTGTCTACAAATGGCACTTGGCACAAGCTTGGAGAAAAGAAG TCAGGACTAACAGAATTGAAACTCAAGCCCACAGGAAGTAAGGTACGTGTCTCCAAAGTGTACTGGACC GAAAATGTGACTGAGCACAGAGAAGTGGCCATCCGCTGCAGCCTGGAGAGTGTAGGCAGCTCAGCCACT CTGTACTCTGTGATGTGGTACTGGAACAGAGAAAACTCTGGAAGTAAATTGCTGGTGCACTTGCAACAT GATGGCTTGCTGGAGTATGGGGAAGAGGGGCTCAGGAGGCACCTGCACTGTTACCGTTCATCCTCTACA GACTTTGTCCTGAAGCTTCATCAGGTGGAGATGGAGGATGCAGGAATGTACTGGTGTAGGGTGGCAGAG TGGCAGCTCCATGGACACCCAAGCAAGTGGATTAATCAAGCATCCGATGAGTCACAGCGGATGGTGCTC ACGGTGCTGCCTTCAGAGCCCACGCTTCCTTCCAGGATCTGCTCCTCGGCCCCTTTACTCTATTTCCTG TTCATCTGTCCCTTCGTCCTGCTCCTCCTTCTGCTCATCTCCCTCCTCTGCTTATACTGGAAGGCCAGG AAGTTGTCAACACTGCGTTCCAACACACGGAAAGAAAAAGCTCTCTGGGTGGACTTGAAAGAGGCTGGA GGTGTGACCACAAATAGGAGGGAAGACGAGGAGGAAGATGAAGGCAAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239827
Blue=ORF Red=Cloning site Green=Tag(s) MAGISYVASFFLLLTKLSIGQREVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLPTNPTQE VQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDEKYYGSYSAKT NLIDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKKQ TDQTTLRIQPAVKDFQVNITADSLFAEGKPLELVCLVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLK NDYKERASQGELQVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRK PAARSVVMSTKNKQQVVWEGETLAFLCKAGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYG VPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKSLESSLQVSL MSRQPQVMLTNTFDLSCVVRAGYSDLKVPLTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKT KVSQSLFRSQLLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQ VQELSINSNTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKFH TEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWT ENVTEHREVAIRCSLESVGSSATLYSVMWYWNRENSGSKLLVHLQHDGLLEYGEEGLRRHLHCYRSSST DFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPTLPSRICSSAPLLYFL FICPFVLLLLLLISLLCLYWKARKLSTLRSNTRKEKALWVDLKEAGGVTTNRREDEEEDEGN TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001256111 |
| ORF Size | 2877 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001256111.2, NP_001243040.1 |
| RefSeq Size | 3334 bp |
| RefSeq ORF | 2880 bp |
| Locus ID | 9398 |
| Protein Families | Transmembrane |
| MW | 109.1 kDa |
| Gene Summary | Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.[UniProtKB/Swiss-Prot Function] |
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