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L1CAM (NM_001143963) Human Untagged Clone
CAT＃: SC326363
L1CAM (untagged)-Human L1 cell adhesion molecule (L1CAM), transcript variant 3
CNY 24,040.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001143963 edited
ATGGTCGTGGCGCTGCGGTACGTGTGGCCTCTCCTCCTCTGCAGCCCCTGCCTGCTTATC CAGATCCCCGAGGAATTGATGGAGCCACCTGTCATCACGGAACAGTCTCCACGGCGCCTG GTTGTCTTCCCCACAGATGACATCAGCCTCAAGTGTGAGGCCAGTGGCAAGCCCGAAGTG CAGTTCCGCTGGACGAGGGATGGTGTCCACTTCAAACCCAAGGAAGAGCTGGGTGTGACC GTGTACCAGTCGCCCCACTCTGGCTCCTTCACCATCACGGGCAACAACAGCAACTTTGCT CAGAGGTTCCAGGGCATCTACCGCTGCTTTGCCAGCAATAAGCTGGGCACCGCCATGTCC CATGAGATCCGGCTCATGGCCGAGGGTGCCCCCAAGTGGCCAAAGGAGACAGTGAAGCCC GTGGAGGTGGAGGAAGGGGAGTCAGTGGTTCTGCCTTGCAACCCTCCCCCAAGTGCAGAG CCTCTCCGGATCTACTGGATGAACAGCAAGATCTTGCACATCAAGCAGGACGAGCGGGTG ACGATGGGCCAGAACGGCAACCTCTACTTTGCCAATGTGCTCACCTCCGACAACCACTCA GACTACATCTGCCACGCCCACTTCCCAGGCACCAGGACCATCATTCAGAAGGAACCCATT GACCTCCGGGTCAAGGCCACCAACAGCATGATTGACAGGAAGCCGCGCCTGCTCTTCCCC ACCAACTCCAGCAGCCACCTGGTGGCCTTGCAGGGGCAGCCATTGGTCCTGGAGTGCATC GCCGAGGGCTTTCCCACGCCCACCATCAAATGGCTGCGCCCCAGTGGCCCCATGCCAGCC GACCGTGTCACCTACCAGAACCACAACAAGACCCTGCAGCTGCTGAAAGTGGGCGAGGAG GATGATGGCGAGTACCGCTGCCTGGCCGAGAACTCACTGGGCAGTGCCCGGCATGCGTAC TATGTCACCGTGGAGGCTGCCCCGTACTGGCTGCACAAGCCCCAGAGCCATCTATATGGG CCAGGAGAGACTGCCCGCCTGGACTGCCAAGTCCAGGGCAGGCCCCAACCAGAGGTCACC TGGAGAATCAACGGGATCCCTGTGGAGGAGCTGGCCAAAGACCAGAAGTACCGGATTCAG CGTGGCGCCCTGATCCTGAGCAACGTGCAGCCCAGTGACACAATGGTGACCCAATGTGAG GCCCGCAACCGGCACGGGCTCTTGCTGGCCAATGCCTACATCTACGTTGTCCAGCTGCCA GCCAAGATCCTGACTGCGGACAATCAGACGTACATGGCTGTCCAGGGCAGCACTGCCTAC CTTCTGTGCAAGGCCTTCGGAGCGCCTGTGCCCAGTGTTCAGTGGCTGGACGAGGATGGG ACAACAGTGCTTCAGGACGAACGCTTCTTCCCCTATGCCAATGGGACCCTGGGCATTCGA GACCTCCAGGCCAATGACACCGGACGCTACTTCTGCCTGGCTGCCAATGACCAAAACAAT GTTACCATCATGGCTAACCTGAAGGTTAAAGATGCAACTCAGATCACTCAGGGGCCCCGC AGCACAATCGAGAAGAAAGGTTCCAGGGTGACCTTCACGTGCCAGGCCTCCTTTGACCCC TCCTTGCAGCCCAGCATCACCTGGCGTGGGGACGGTCGAGACCTCCAGGAGCTTGGGGAC AGTGACAAGTACTTCATAGAGGATGGGCGCCTGGTCATCCACAGCCTGGACTACAGCGAC CAGGGCAACTACAGCTGCGTGGCCAGTACCGAACTGGATGTGGTGGAGAGTAGGGCACAG CTCTTGGTGGTGGGGAGCCCTGGGCCGGTGCCACGGCTGGTGCTGTCCGACCTGCACCTG CTGACGCAGAGCCAGGTGCGCGTGTCCTGGAGTCCTGCAGAAGACCACAATGCCCCCATT GAGAAATATGACATTGAATTTGAGGACAAGGAAATGGCGCCTGAAAAATGGTACAGTCTG GGCAAGGTTCCAGGGAACCAGACCTCTACCACCCTCAAGCTGTCGCCCTATGTCCACTAC ACCTTTAGGGTTACTGCCATAAACAAATATGGCCCCGGGGAGCCCAGCCCGGTCTCTGAG ACTGTGGTCACACCTGAGGCAGCCCCAGAGAAGAACCCTGTGGATGTGAAGGGGGAAGGA AATGAGACCACCAATATGGTCATCACGTGGAAGCCGCTCCGGTGGATGGACTGGAACGCC CCCCAGGTTCAGTACCGCGTGCAGTGGCGCCCTCAGGGGACACGAGGGCCCTGGCAGGAG CAGATTGTCAGCGACCCCTTCCTGGTGGTGTCCAACACGTCCACCTTCGTGCCCTATGAG ATCAAAGTCCAGGCCGTCAACAGCCAGGGCAAGGGACCAGAGCCCCAGGTCACTATCGGC TACTCTGGAGAGGACTACCCCCAGGCAATCCCTGAGCTGGAAGGCATTGAAATCCTCAAC TCAAGTGCCGTGCTGGTCAAGTGGCGGCCGGTGGACCTGGCCCAGGTCAAGGGCCACCTC CGCGGATACAATGTGACGTACTGGAGGGAGGGCAGTCAGAGGAAGCACAGCAAGAGACAT ATCCACAAAGACCATGTGGTGGTGCCCGCCAACACCACCAGTGTCATCCTCAGTGGCTTG CGGCCCTATAGCTCCTACCACCTGGAGGTGCAGGCCTTTAACGGGCGAGGATCGGGGCCC GCCAGCGAGTTCACCTTCAGCACCCCAGAGGGAGTGCCTGGCCACCCCGAGGCGTTGCAC CTGGAGTGCCAGTCGAACACCAGCCTGCTGCTGCGCTGGCAGCCCCCACTCAGCCACAAC GGCGTGCTCACCGGCTACGTGCTCTCCTACCACCCCCTGGATGAGGGGGGCAAGGGGCAA CTGTCCTTCAACCTTCGGGACCCCGAACTTCGGACACACAACCTGACCGATCTCAGCCCC CACCTGCGGTACCGCTTCCAGCTTCAGGCCACCACCAAAGAGGGCCCTGGTGAAGCCATC GTACGGGAAGGAGGCACTATGGCCTTGTCTGGGATCTCAGATTTTGGCAACATCTCAGCC ACAGCGGGTGAAAACTACAGTGTCGTCTCCTGGGTCCCCAAGGAGGGCCAGTGCAACTTC AGGTTCCATATCTTGTTCAAAGCCTTGGGAGAAGAGAAGGGTGGGGCTTCCCTTTCGCCA CAGTATGTCAGCTACAACCAGAGCTCCTACACGCAGTGGGACCTGCAGCCTGACACTGAC TACGAGATCCACTTGTTTAAGGAGAGGATGTTCCGGCACCAAATGGCTGTGAAGACCAAT GGCACAGGCCGCGTGAGGCTCCCTCCTGCTGGCTTCGCCACTGAGGGCTGGTTCATCGGC TTTGTGAGTGCCATCATCCTCCTGCTCCTCGTCCTGCTCATCCTCTGCTTCATCAAGCGC AGCAAGGGCGGCAAATACTCAGTGAAGGATAAGGAGGACACCCAGGTGGACTCTGAGGCC CGACCGATGAAAGATGAGACCTTCGGCGAGTACAGTGACAACGAGGAGAAGGCCTTTGGC AGCAGCCAGCCATCGCTCAACGGGGACATCAAGCCCCTGGGCAGTGACGACAGCCTGGCC GATTATGGGGGCAGCGTGGATGTTCAGTTCAACGAGGATGGTTCGTTCATTGGCCAGTAC AGTGGCAAGAAGGAGAAGGAGGCGGCAGGGGGCAATGACAGCTCAGGGGCCACTTCCCCC ATCAACCCTGCCGTGGCCCTAGAATAG |
| Restriction Sites | Please inquire |
| ACCN | NM_001143963 |
| Insert Size | 5200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001143963.1, NP_001137435.1 |
| RefSeq Size | 5019 bp |
| RefSeq ORF | 3747 bp |
| Locus ID | 3897 |
| UniProt ID | P32004 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Axon guidance, Cell adhesion molecules (CAMs) |
| Gene Summary | The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013] Transcript Variant: This variant (3, also known as SV-L1CAM) lacks two alternate in-frame exons, one in the 5' coding region and the other (neuron-specific exon) in the 3' coding region, compared to variant 4. The resulting isoform (3) is shorter, and lacks an internal segment in the N-terminus and is missing a tyrosine-based sorting motif in the C-terminus, compared to isoform 1. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227350 | L1CAM (Myc-DDK-tagged)-Human L1 cell adhesion molecule (L1CAM), transcript variant 3 |
CNY 12,450.00 |
|
| RC227350L3 | Lenti-ORF clone of L1CAM (Myc-DDK-tagged)-Human L1 cell adhesion molecule (L1CAM), transcript variant 3 |
CNY 14,350.00 |
|
| RC227350L4 | Lenti-ORF clone of L1CAM (mGFP-tagged)-Human L1 cell adhesion molecule (L1CAM), transcript variant 3 |
CNY 14,350.00 |
|
| RG227350 | L1CAM (tGFP-tagged) - Human L1 cell adhesion molecule (L1CAM), transcript variant 3 |
CNY 13,680.00 |
