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CARD4 (NOD1) (NM_006092) Human Untagged Clone
CAT＃: SC323936
NOD1 (untagged)-Human nucleotide-binding oligomerization domain containing 1 (NOD1)
CNY 6,984.00
CNY 7,220.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CARD4; CLR7.1; NLRC1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_006092.1
CCCGGCCCCGGCGTCCCCGGACCATGGCGCTCTCCGGGCTCTTCTCTAGCTCTCAGCGGC
TGCGAAGTCTGTAAACCTGGTGGCCAAGTGATTGTAAGTCAGGAGACTTTCCTTCGGTTT CTGCCTTTGATGGCAAGAGGTGGAGATTGTGGCGGCGATTACAGAAAACGTCTGGGAAGA CAAGTTGCTGTTTTTATGGGAATCGCAGGCTTGGAAGAGACAGAAGCAATTCCAGAAATA AATTGGAAATTGAAGATTTAAACAATGTTGTTTTAAAACATTCTAACTTCAAAGAATGAT GCCAGAAACTTAAAAAGGGGCTGCGCAGAGTAGCAGGGGCCCTGGAGGGCGCGGCCTGAA TCCTGATTGCCCTTCTGCTGAGAGGACACACGCAGCTGAAGATGAATTTGGGAAAAGTAG CCGCTTGCTACTTTAACTATGGAAGAGCAGGGCCACAGTGAGATGGAAATAATCCCATCA GAGTCTCACCCCCACATTCAATTACTGAAAAGCAATCGGGAACTTCTGGTCACTCACATC CGCAATACTCAGTGTCTGGTGGACAACTTGCTGAAGAATGACTACTTCTCGGCCGAAGAT GCGGAGATTGTGTGTGCCTGCCCCACCCAGCCTGACAAGGTCCGCAAAATTCTGGACCTG GTACAGAGCAAGGGCGAGGAGGTGTCCGAGTTCTTCCTCTACTTGCTCCAGCAACTCGCA GATGCCTACGTGGACCTCAGGCCTTGGCTGCTGGAGATCGGCTTCTCCCCTTCCCTGCTC ACTCAGAGCAAAGTCGTGGTCAACACTGACCCAGTGAGCAGGTATACCCAGCAGCTGCGA CACCATCTGGGCCGTGACTCCAAGTTCGTGCTGTGCTATGCCCAGAAGGAGGAGCTGCTG CTGGAGGAGATCTACATGGACACCATCATGGAGCTGGTTGGCTTCAGCAATGAGAGCCTG GGCAGCCTGAACAGCCTGGCCTGCCTCCTGGACCACACCACCGGCATCCTCAATGAGCAG GGTGAGACCATCTTCATCCTGGGTGATGCTGGGGTGGGCAAGTCCATGCTGCTACAGCGG CTGCAGAGCCTCTGGGCCACGGGCCGGCTAGACGCAGGGGTCAAATTCTTCTTCCACTTT CGCTGCCGCATGTTCAGCTGCTTCAAGGAAAGTGACAGGCTGTGTCTGCAGGACCTGCTC TTCAAGCACTACTGCTACCCAGAGCGGGACCCCGAGGAGGTGTTTGCCTTCCTGCTGCGC TTCCCCCACGTGGCCCTCTTCACCTTCGATGGCCTGGACGAGCTGCACTCGGACTTGGAC CTGAGCCGTGTGCCTGACAGCTCCTGCCCCTGGGAGCCTGCCCACCCCCTGGTCTTGCTG GCCAACCTGCTCAGTGGGAAGCTGCTCAAGGGGGCTAGCAAGCTGCTCACAGCCCGCACA GGCATCGAGGTCCCGCGCCAGTTCCTGCGGAAGAAGGTGCTTCTCCGGGGCTTCTCCCCC AGCCACCTGCGCGCCTATGCCAGGAGGATGTTCCCCGAGCGGGCCCTGCAGGACCGCCTG CTGAGCCAGCTGGAGGCCAACCCCAACCTCTGCAGCCTGTGCTCTGTGCCCCTCTTCTGC TGGATCATCTTCCGGTGCTTCCAGCACTTCCGTGCTGCCTTTGAAGGCTCACCACAGCTG CCCGACTGCACGATGACCCTGACAGATGTCTTCCTCCTGGTCACTGAGGTCCATCTGAAC AGGATGCAGCCCAGCAGCCTGGTGCAGCGGAACACACACAGCCCAGTGGAGACCCTCCAC GCCGGCCGGGACACTCTGTGCTCGCTGGGGCAGGTGGCCCACCGGGGCATGGAGAAGAGC CTCTTTGTCTTCACCCAGGAGGAGGTGCAGGCCTCCGGGCTGCAGGAGAGAGACATGCAG CTGGGCTTCCTGCGGGCTTTGCCGGAGCTGGGCCCCGGGGGTGACCAGCAGTCCTATGAG TTTTTCCACCTCACCCTCCAGGCCTTCTTTACAGCCTTCTTCCTCGTGCTGGACGACAGG GTGGGCACTCAGGAGCTGCTCAGGTTCTTCCAGGAGTGGATGCCCCCTGCGGGGGCAGCG ACCACGTCCTGCTATCCTCCCTTCCTCCCGTTCCAGTGCCTGCAGGGCAGTGGTCCGGCG CGGGAAGACCTCTTCAAGAACAAGGATCACTTCCAGTTCACCAACCTCTTCCTGTGCGGG CTGTTGTCCAAAGCCAAACAGAAACTCCTGCGGCATCTGGTGCCCGCGGCAGCCCTGAGG AGAAAGCGCAAGGCCCTGTGGGCACACCTGTTTTCCAGCCTGCGGGGCTACCTGAAGAGC CTGCCCCGCGTTCAGGTCGAAAGCTTCAACCAGGTGCAGGCCATGCCCACGTTCATCTGG ATGCTGCGCTGCATCTACGAGACACAGAGCCAGAAGGTGGGGCAGCTGGCGGCCAGGGGC ATCTGCGCCAACTACCTCAAGCTGACCTACTGCAACGCCTGCTCGGCCGACTGCAGCGCC CTCTCCTTCGTCCTGCATCACTTCCCCAAGCGGCTGGCCCTAGACCTAGACAACAACAAT CTCAACGACTACGGCGTGCGGGAGCTGCAGCCCTGCTTCAGCCGCCTCACTGTTCTCAGA CTCAGCGTAAACCAGATCACTGACGGTGGGGTAAAGGTGCTAAGCGAAGAGCTGACCAAA TACAAAATTGTGACCTATTTGGGTTTATACAACAACCAGATCACCGATGTCGGAGCCAGG TACGTCACCAAAATCCTGGATGAATGCAAAGGCCTCACGCATCTTAAACTGGGAAAAAAC AAAATAACAAGTGAAGGAGGGAAGTATCTCGCCCTGGCTGTGAAGAACAGCAAATCAATC TCTGAGGTTGGGATGTGGGGCAATCAAGTTGGGGATGAAGGAGCAAAAGCCTTCGCAGAG GCTCTGCGGAACCACCCCAGCTTGACCACCCTGAGTCTTGCGTCCAACGGCATCTCCACA GAAGGAGGAAAGAGCCTTGCGAGGGCCCTGCAGCAGAACACGTCTCTAGAAATACTGTGG CTGACCCAAAATGAACTCAACGATGAAGTGGCAGAGAGTTTGGCAGAAATGTTGAAAGTC AACCAGACGTTAAAGCATTTATGGCTTATCCAGAATCAGATCACAGCTAAGGGGACTGCC CAGCTGGCAGATGCGTTACAGAGCAACACTGGCATAACAGAGATTTGCCTAAATGGAAAC CTGATAAAACCAGAGGAGGCCAAAGTCTATGAAGATGAGAAGCGGATTATCTGTTTCTGA GAGGATGCTTTCCTGTTCATGGGGTTTTTGCCCTGGAGCCTCAGCAGCAAATGCCACTCT GGGCAGTCTTTTGTGTCAGTGTCTTAAAGGGGCCTGCGCAGGCGGGACTATCAGGAGTCC ACTGCCTCCATGATGCAAGCCAGCTTCCTGTGCAGAAGGTCTGGTCGGCAAACTCCCTAA GTACCCGCTACAATTCTGCAGAAAAAGAATGTGTCTTGCGAGCTGTTGTAGTTACAGTAA ATACACTGTGAAGAGACTTTATTGCCTATTATAATTATTTTTATCTGAAGCTAGAGGAAT AAAGCTGTGAGCAAACAGAGGAGGCCAGCCTCACCTCATTCCAACACCTGCCATAGGGAC CAACGGGAGCGAGTTGGTCACCGCTCTTTTCATTGAAGAGTTGAGGATGTGGCACAAAGT TGGTGCCAAGCTTCTTGAATAAAACGTGTTTGATGGATTAGTATTATACCTGAAATATTT TCTTCCTTCTCAGCACTTTCCCATGTATTGATACTGGTCCCACTTCACAGCTGGAGACAC CGGAGTATGTGCAGTGTGGGATTTGACTCCTCCAAGGTTTTGTGGAAAGTTAATGTCAAG GAAAGGATGCACCACGGGCTTTTAATTTTAATCCTGGAGTCTCACTGTCTGCTGGCAAAG ATAGAGAATGCCCTCAGCTCTTAGCTGGTCTAAGAATGACGATGCCTTCAAAATGCTGCT TCCACTCAGGGCTTCTCCTCTGCTAGGCTACCCTCCTCTAGAAGGCTGAGTACCATGGGC TACAGTGTCTGGCCTTGGGAAGAAGTGATTCTGTCCCTCCAAAGAAATAGGGCATGGCTT GCCCCTGTGGCCCTGGCATCCAAATGGCTGCTTTTGTCTCCCTTACCTCGTGAAGAGGGG AAGTCTCTTCCTGCCTCCCAAGCAGCTGAAGGGTGACTAAACGGGCGCCAAGACTCAGGG GATCGGCTGGGAACTGGGCCAGCAGAGCATGTTGGACACCCCCCACCATGGTGGGCTTGT GGTGGCTGCTCCATGAGGGTGGGGGTGATACTACTAGATCACTTGTCCTCTTGCCAGCTC ATTTGTTAATAAAATACTGAAAACACTAAAAAAAAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_006092 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006092.1, NP_006083.1 |
| RefSeq Size | 4390 bp |
| RefSeq ORF | 2862 bp |
| Locus ID | 10392 |
| UniProt ID | Q9Y239 |
| Domains | CARD, LRR, LRR_RI |
| Protein Families | Druggable Genome |
| Protein Pathways | Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway |
| Gene Summary | This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MyD88 and TNF Receptor-Associated Factor 6 Are Critical Signal Transducers in Helicobacter pylori-Infected Human Epithelial Cells
,Yoshihiro Hirata, Tomoya Ohmae, Wataru Shibata, Shin Maeda, Keiji Ogura, Haruhiko Yoshida, Takao Kawabe, and Masao Omata,
J. Immunol. 2006 Mar 15;176(6):3796-803.
[NOD1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203759 | NOD1 (Myc-DDK-tagged)-Human nucleotide-binding oligomerization domain containing 1 (NOD1) |
CNY 6,976.00 |
|
| RC203759L1 | Lenti ORF clone of Human nucleotide-binding oligomerization domain containing 1 (NOD1), Myc-DDK-tagged |
CNY 9,376.00 |
|
| RC203759L2 | Lenti ORF clone of Human nucleotide-binding oligomerization domain containing 1 (NOD1), mGFP tagged |
CNY 9,030.00 |
|
| RC203759L3 | Lenti ORF clone of Human nucleotide-binding oligomerization domain containing 1 (NOD1), Myc-DDK-tagged |
CNY 9,376.00 |
|
| RC203759L4 | Lenti ORF clone of Human nucleotide-binding oligomerization domain containing 1 (NOD1), mGFP tagged |
CNY 9,376.00 |
|
| RG203759 | NOD1 (tGFP-tagged) - Human nucleotide-binding oligomerization domain containing 1 (NOD1) |
CNY 8,576.00 |
|
| SC316302 | NOD1 (untagged)-Human nucleotide-binding oligomerization domain containing 1 (NOD1) |
CNY 6,984.00 |
