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CARD4 (NOD1) (NM_006092) Human Untagged Clone
CAT＃: SC316302
NOD1 (untagged)-Human nucleotide-binding oligomerization domain containing 1 (NOD1)
CNY 6,984.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CARD4; CLR7.1; NLRC1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_006092 edited
CTCTAGCTCTCAGCGGCTGCGAAGTCTGTAAACCTGGTGGCCAAGTGATTGTAAGTCAGG AGACTTTCCTTCGGTTTCTGCCTTTGATGGCAATTTCCTTCGGTTTCTGCCTTTGATGGC AAGAGGTGGAGATTGTGGCGGCGATTACAGAGAACGTCTGGGAAGACAAGTTGCTGTTTT TATGGGAATCGCAGGCTTGGAAGAGACAGAAGCAATTCCAGAAATAAATTGGAAATTGAA GATTTAAACAATGTTGTTTTAAAATATTCTAACTTCAAAGAATGATGCCAGAAACTTAAA AAGGGGCTGCGCAGAGTAGCAGGGGCCCTGGAGGGCGCGGCCTGAATCCTGATTGCCCTT CTGCTGAGAGGACACACGCAGCTGAAGATGAATTTGGGAAAAGTAGCCGCTTGCTACTTT AACTATGGAAGAGCAGGGCCACAGTGAGATGGAAATAATCCCATCAGAGTCTCACCCCCA CATTCAATTACTGAAAAGCAATCGGGAACTTCTGGTCACTCACATCCGCAATACTCAGTG TCTGGTGGACAACTTGCTGAAGAATGACTACTTCTCGGCCGAAGATGCGGAGATTGTGTG TGCCTGCCCCACCCAGCCTGACAAGGTCCGCAAAATTCTGGACCTGGTACAGAGCAAGGG CGAGGAGGTGTCCGAGTTCTTCCTCTACTTGCTCCAGCAACTCGCAGATGCCTACGTGGA CCTCAGGCCTTGGCTGCTGGAGATCGGCTTCTCCCCTTCCCTGCTCACTCAGAGCAAAGT CGTGGTCAACACTGACCCAGTGAGCAGGTATACCCAGCAGCTGCGACACCATCTGGGCCG TGACTCCAAGTTCGTGCTGTGCTATGCCCAGAAGGAGGAGCTGCTGCTGGAGGAGATCTA CATGGACACCATCATGGAGCTGGTTGGCTTCAGCAATGAGAGCCTGGGCAGCCTGAACAG CCTGGCCTGCCTCCTGGACCACACCACCGGCATCCTCAATGAGCAGGGTGAGACCATCTT CATCCTGGGTGATGCTGGGGTGGGCAAGTCCATGCTGCTACAGCGGCTGCAGAGCCTCTG GGCCACGGGCCGGCTAGACGCAGGGGTCAAATTCTTCTTCCACTTTCGCTGCCGCATGTT CAGCTGCTTCAAGGAAAGTGACAGGCTGTGTCTGCAGGACCTGCTCTTCAAGCACTACTG CTACCCAGAGCGGGACCCCGAGGAGGTGTTTGCCTTCCTGCTGCGCTTCCCCCACGTGGC CCTCTTCACCTTCGATGGCCTGGACGAGCTGCACTCGGACTTGGACCTGAGCCGCGTGCC TGACAGCTCCTGCCCCTGGGAGCCTGCCCACCCCCTGGTCTTGCTGGCCAACCTGCTCAG TGGGAAGCTGCTCAAGGGGGCTAGCAAGCTGCTCACAGCCCGCACAGGCATCGAGGTCCC GCGCCAGTTCCTGCGGAAGAAGGTGCTTCTCCGGGGCTTCTCCCCCAGCCACCTGCGCGC CTATGCCAGGAGGATGTTCCCCGAGCGGGCCCTGCAGGACCGCCTGCTGAGCCAGCTGGA GGCCAACCCCAACCTCTGCAGCCTGTGCTCTGTGCCCCTCTTCTGCTGGATCATCTTCCG GTGCTTCCAGCACTTCCGTGCTGCCTTTGAAGGCTCACCACAGCTGCCCGACTGCACGAT GACCCTGACAGATGTCTTCCTCCTGGTCACTGAGGTCCATCTGAACAGGATGCAGCCCAG CAGCCTGGTGCAGCGGAACACACGCAGCCCAGTGGAGACCCTCCACGCCGGCCGGGACAC TCTGTGCTCGCTGGGGCAGGTGGCCCACCGGGGCATGGAGAAGAGCCTCTTTGTCTTCAC CCAGGAGGAGGTGCAGGCCTCCGGGCTGCAGGAGAGAGACATGCAGCTGGGCTTCCTGCG GGCTTTGCCGGAGCTGGGCCCCGGGGGTGACCAGCAGTCCTATGAGTTTTTCCACCTCAC CCTCCAGGCCTTCTTTACAGCCTTCTTCCTCGTGCTGGACGACAGGGTGGGCACTCAGGA GCTGCTCAGGTTCTTCCAGGAGTGGATGCCCCCTGCGGGGGCAGCGACCACGTCCTGCTA TCCTCCCTTCCTCCCGTTCCAGTGCCTGCAGGGCAGTGGTCCGGCGCGGGAAGACCTCTT CAAGAACAAGGATCACTTCCAGTTCACCAACCTCTTCCTGTGCGGGCTGTTGTCCAAAGC CAAACAGAAACTCCTGCGGCATCTGGTGCCCGCGGCAGCCCTGAGGAGAAAGCGCAAGGC CCTGTGGGCACACCTGTTTTCCAGCCTGCGGGGCTACCTGAAGAGCCTGCCCCGCGTTCA GGTCGAAAGCTTCAACCAGGTGCAGGCCATGCCCACGTTCATCTGGATGCTGCGCTGCAT CTACGAGACACAGAGCCAGAAGGTGGGGCAGCTGGCGGCCAGGGGCATCTGCGCCAACTA CCTCAAGCTGACCTACTGCAACGCCTGCTCGGCCGACTGCAGCGCCCTCTCCTTCGTCCT GCATCACTTCCCCAAGCGGCTGGCCCTAGACCTAGACAACAACAATCTCAACGACTACGG CGTGCGGGAGCTGCAGCCCTGCTTCAGCCGCCTCACTGTTCTCAGACTCAGCGTAAACCA GATCACTGACGGTGGGGTAAAGGTGCTAAGCGAAGAGCTGACCAAATACAAAATTGTGAC CTATTTGGGTTTATACAACAACCAGATCACCGATGTCGGAGCCAGGTACGTCACCAAAAT CCTGGATGAATGCAAAGGCCTCACGCATCTTAAACTGGGAAAAAACAAAATAACAAGTGA AGGAGGGAAGTATCTCGCCCTGGCTGTGAAGAACAGCAAATCAATCTCTGAGGTTGGGAT GTGGGGCAATCAAGTTGGGGATGAAGGAGCAAAAGCCTTCGCAGAGGCTCTGCGGAACCA CCCCAGCTTGACCACCCTGAGTCTTGCGTCCAACGGCATCTCCACAGAAGGAGGAAAGAG CCTTGCGAGGGCCCTGCAGCAGAACACGTCTCTAGAAATACTGTGGCTGACCCAAAATGA ACTCAACGATGAAGTGGCAGAGAGTTTGGCAGAAATGTTGAAAGTCAACCAGACGTTAAA GCATTTATGGCTTATCCAGAATCAGATCACAGCTAAGGGGACTGCCCAGCTGGCAGATGC GTTACAGAGCAACACTGGCATAACAGAGATTTGCCTAAATGGAAACCTGATAAAACCAGA GGAGGCCAAAGTCTATGAAGATGAGAAGCGGATTATCTGTTTCTGAGAGGATGCTTTCCT GTTCATGGGGTTTTTGCCCTGGAGCCTCAGCAGCAAATGCCACTCTGGGCAGTCTTTTGT GTCAGTGTCTTAAAGGGGCCTGCGCAGGCGGGACTATCAGGAGTCCACTGCCTCCATGAT GCAAGCCAGCTTCCTGTGCAGAAGGTCTGGTCGGCAAACTCCCTAAGTACCCGCTACAAT TCTGCAGAAAAAGAATGTGTCTTGCGAGCTGTTGTAGTTACAGTAAATACACTGTGAAGA GACTTTATTGCCTATTATAATTATTTTTATCTGAAGCTAGAGGAATAAAGCTGTGAGCAA ACAGAGGAGGCCAGCCTCACCTCATTCCAACACCTGCCATAGGGACCAACGGGAGCGAGT TGGTCACCGCTCTTTTCATTGAAGAGTTGAGGATGTGGCACAAAGTTGGTGCCAAGCTTC TTGAATAAAACGTGTTTGATGGATTAGTATTATACCTGAAATATTTTCTTCCTTCTCAGC ACTTTCCCATGTATTGATACTGGTCCCACTTCACAGCTGGAGACACCGGAGTATGTGCAG TGTGGGATTTGACTCCTCCAAGGTTTTGTGGAAAGTTAATGTCAAGGAAAGGATGCACCA CGGGCTTTTAATTTTAATCCTGGAGTCTCACTGTCTGCTGGCAAAGATAGAGAATGCCCT CAGCTCTTAGCTGGTCTAAGAATGACGATGCCTTCAAAATGCTGCTTCCACTCAGGGCTT CTCCTCTGCTAGGCTACCCTCCTCTAGAAGGCTGAGTACCATGGGCTACAGTGTCTGGCC TTGGGAAGAAGTGATTCTGTCCCTCCAAAGAAATAGGGCATGGCTTGCCCCTGTGGCCCT GGCATCCAAATGGCTGCTTTTGTCTCCCTTACCTCGTGAAGAGGGGAAGTCTCTTCCTGC CTCCCAAGCAGCTGAAGGGTGACTAAACGGGCGCCAAGACTCAGGGGATCGGCTGGGAAC TGGGCCAGCAGAGCATGTTGGACACCCCCCACCATGGTGGGCTTGTGGTGGCTGCTCCAT GAGGGTGGGGGTGATACTACTAGATCACTTGTCCTCTTGCCCGCTCATTTGTTAATAAAA TACTGAAAAC >OriGene 5' read for NM_006092 unedited
GGCTACTTGTATACGACTCCTATAGGGCGGCCGCGTATCTATCCCGGGATATCCGTCGAC CCACGCGTCCGCCCGGCCCCGGCGTCCCCGGACCATGGCGCTCTCCGGGCTCTTCTCTAG CTCTCAGCGGCTGCGAAGTCTGTAAACCTGGTGGCCAAGTGATTGTAAGTCAGGAGACTT TCCTTCGGTTTCTGCCTTTGATGGCAAGAGGTGGAGATTGTGGCGGCGATTACAGAAAAC GTCTGGGAAGACAAGTTGCTGTTTTTATGGGAATCGCAGGCTTGGAAGAGACAGAAGCAA TTCCAGAAATAAATTGGAAATTGAAGATTTAAACAATGTTGTTTTAAAACATTCTAACTT CAAAGAATGATGCCAGAAACTTAAAAAGGGGCTGCGCAGAGTAGCAGGGGCCCTGGAGGG CGCGGCCTGAATCCTGATTGCCCTTCTGCTGAGAGGACACACGCAGCTGAAGATGAATTT GGGAAAAGTAGCCGCTTGCTACTTTAACTATGGAAGAGCAGGGCCACAGTGAGATGGAAA TAATCCCATCAGAGTCTCACCCCCACATTCAATTACTGAAAAGCAATCGGGAACTTCTGG TCACTCACATCCGCAATACTCAGTGTCTGGTGGACAACTTGCTGAAGAATGACTACTTCT CGGCCGAAGATGCGGAGATTGTGTGTGCCTGCCCCACCCAGCCTGACAAGGTCCGCAAAA TTCTGGACCTGGTACAGAGCAAGGGCGAGGAGGTGTCCGAGTTCTTCCTCTACTTGCTCC AGCAACTCGCAGATGCCTACGTGGACCTCAGCCTTGGCTGCTGGAGATCGGCTTCTCCCT TCCCTGCTCACTCAGAGCAAAGTCGTGGTCAACACTGACC |
| Restriction Sites | Please inquire |
| ACCN | NM_006092 |
| Insert Size | 4400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006092.1, NP_006083.1 |
| RefSeq Size | 4390 bp |
| RefSeq ORF | 2862 bp |
| Locus ID | 10392 |
| UniProt ID | Q9Y239 |
| Domains | CARD, LRR, LRR_RI |
| Protein Families | Druggable Genome |
| Protein Pathways | Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway |
| Gene Summary | This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection
,Wenli Liu, Ming Yan, Yueqin Liu, Ruihong Wang, Cuiling Li, Chuxia Deng, Aparna Singh, William G. Coleman, Jr., and Griffin P. Rodgers,
PNAS, Jun 2010; 107: 11056 - 11061
[NOD1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203759 | NOD1 (Myc-DDK-tagged)-Human nucleotide-binding oligomerization domain containing 1 (NOD1) |
CNY 6,976.00 |
|
| RC203759L1 | Lenti ORF clone of Human nucleotide-binding oligomerization domain containing 1 (NOD1), Myc-DDK-tagged |
CNY 9,376.00 |
|
| RC203759L2 | Lenti ORF clone of Human nucleotide-binding oligomerization domain containing 1 (NOD1), mGFP tagged |
CNY 9,030.00 |
|
| RC203759L3 | Lenti ORF clone of Human nucleotide-binding oligomerization domain containing 1 (NOD1), Myc-DDK-tagged |
CNY 9,376.00 |
|
| RC203759L4 | Lenti ORF clone of Human nucleotide-binding oligomerization domain containing 1 (NOD1), mGFP tagged |
CNY 9,376.00 |
|
| RG203759 | NOD1 (tGFP-tagged) - Human nucleotide-binding oligomerization domain containing 1 (NOD1) |
CNY 8,576.00 |
|
| SC323936 | NOD1 (untagged)-Human nucleotide-binding oligomerization domain containing 1 (NOD1) |
CNY 6,984.00 |
