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Complement C7 (C7) (NM_000587) Human Untagged Clone
CAT＃: SC322733
C7 (untagged)-Human complement component 7 (C7)
CNY 6,184.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322733
GGCAGCCTGCTGGGCTCTTCCTGCTGTTGAAAACTTACCCGGCCCTTACAGAGGAAATCT
TCCTCCTCTCTTCTGCCCTGAATGTTTTCCCAAACATGAAGGTGATAAGCTTATTCATTT TGGTGGGATTTATAGGAGAGTTCCAAAGTTTTTCAAGTGCCTCCTCTCCAGTCAACTGCC AGTGGGACTTCTATGCCCCTTGGTCAGAATGCAATGGCTGTACCAAGACTCAGACTCGCA GGCGGTCAGTTGCTGTGTATGGGCAGTATGGAGGCCAGCCTTGTGTTGGAAATGCTTTTG AAACACAGTCCTGTGAACCTACAAGAGGATGTCCAACAGAGGAGGGATGTGGAGAGCGTT TCAGGTGCTTTTCAGGTCAGTGCATCAGCAAATCATTGGTTTGCAATGGGGATTCTGACT GTGATGAAGACAGTGCTGATGAAGACAGATGTGAGGACTCAGAAAGGAGACCTTCCTGTG ATATCGATAAACCTCCTCCTAACATAGAACTTACTGGAAATGGTTACAATGAACTCACTG GCCAGTTTAGGAACAGAGTCATCAATACCAAAAGTTTTGGTGGTCAATGTAGAAAGGTGT TTAGTGGGGATGGAAAAGATTTCTACAGGCTGAGTGGAAATGTCCTGTCCTATACATTCC AGGTGAAAATAAATAATGATTTTAATTATGAATTTTACAATAGTACTTGGTCTTATGTAA AACATACGTCGACAGAACACACATCATCTAGTCGGAAGCGCTCCTTTTTTAGATCTTCAT CATCTTCTTCACGCAGTTATACTTCACATACCAATGAAATCCATAAAGGAAAGAGTTACC AACTGCTGGTTGTTGAGAACACTGTTGAAGTGGCTCAGTTCATTAATAACAATCCAGAAT TTTTACAACTTGCTGAGCCATTCTGGAAGGAGCTTTCCCACCTCCCCTCTCTGTATGACT ACAGTGCCTACCGAAGATTAATCGACCAGTACGGGACACATTATCTGCAATCTGGGTCGT TAGGAGGAGAATACAGAGTTCTATTTTATGTGGACTCAGAAAAATTAAAACAAAATGATT TTAATTCAGTCGAAGAAAAGAAATGTAAATCCTCAGGTTGGCATTTTGTCGTTAAATTTT CAAGTCATGGATGCAAGGAACTGGAAAACGCTTTAAAAGCTGCTTCAGGAACCCAGAACA ATGTATTGCGAGGAGAACCGTTCATCAGAGGGGGAGGTGCAGGCTTCATATCTGGCCTTA GTTACCTAGAGCTGGACAATCCTGCTGGAAACAAAAGGCGATATTCTGCCTGGGCAGAAT CTGTGACTAATCTTCCTCAAGTCATAAAACAAAAGCTGACACCTTTATATGAGCTGGTAA AGGAAGTACCTTGTGCCTCTGTGAAAAAACTATACCTGAAATGGGCTCTTGAAGAGTATC TGGATGAATTTGACCCCTGTCATTGCCGGCCTTGTCAAAATGGTGGTTTGGCTACTGTTG AGGGGACCCATTGTCTGTGCCATTGCAAACCGTACACATTTGGTGCGGCGTGTGAGCAAG GAGTCCTCGTAGGGAATCAAGCAGGAGGGGTTGATGGAGGTTGGAGTTGCTGGTCCTCTT GGAGCCCCTGTGTCCAAGGGAAGAAAACAAGAAGCCGTGAATGCAATAACCCACCTCCCA GTGGGGGTGGGAGATCCTGCGTTGGAGAAACGACAGAAAGCACACAATGCGAAGATGAGG AGCTGGAGCACTTGAGGTTGCTTGAACCACATTGCTTTCCTTTGTCTTTGGTTCCAACAG AATTCTGTCCATCACCTCCTGCCTTGAAAGATGGATTTGTTCAAGATGAAGGTACAATGT TTCCTGTGGGGAAAAATGTAGTGTACACTTGCAATGAAGGATACTCTCTTATTGGAAACC CAGTGGCCAGATGTGGAGAAGATTTACGGTGGCTTGTTGGGGAAATGCATTGTCAGAAAA TTGCCTGTGTTCTACCTGTACTGATGGATGGCATACAGAGTCACCCCCAAAAACCTTTCT ACACAGTTGGTGAGAAGGTGACTGTTTCCTGTTCAGGTGGCATGTCCTTAGAAGGTCCTT CAGCATTTCTCTGTGGCTCCAGCCTTAAGTGGAGTCCTGAGATGAAGAATGCCCGCTGTG TACAAAAAGAAAATCCGTTAACACAGGCAGTGCCTAAATGTCAGCGCTGGGAGAAACTGC AGAATTCAAGATGTGTTTGTAAAATGCCCTACGAATGTGGACCTTCCTTGGATGTATGTG CTCAAGATGAGAGAAGCAAAAGGATACTGCCTCTGACAGTTTGCAAGATGCATGTTCTCC ACTGTCAGGGTAGAAATTACACCCTTACTGGTAGGGACAGCTGTACTCTGCCTGCCTCAG CTGAGAAAGCTTGTGGTGCCTGCCCACTGTGGGGAAAATGTGATGCTGAGAGCAGCAAAT GTGTCTGCCGAGAAGCATCGGAGTGCGAGGAAGAAGGGTTTAGCATTTGTGTGGAAGTGA ACGGCAAGGAGCAGACGATGTCTGAGTGTGAGGCGGGCGCTCTGAGATGCAGAGGGCAGA GCATCTCTGTCACCAGCATAAGGCCTTGTGCTGCGGAAACCCAGTAGGCTCCTGGAGGCC CTGGTCAGCTTGCTTGGAATCCAGCAGGCAGCTGGGGCTGAGTGAAAACATCTGCACAAC TGGGCACTGGACAGCTTTTCCTTCTTCTCCAGTGTCTACCTTCCTCCTCAACTCCCAGCC ATCTGTATAAACACAATCCTTTGTTCTCCCAAATCTGAATCGAATTACTCTTTTGCCTCC TTTTTAATGTCAGTAAGGATATGAGCCTTTGCACAGGCTGGCTGCGTGTTCTTGAAATAG GTGTTACCTTCTCTGGGCCTTGGTTTTTTAAAATCTGTAAAATTAGAGGATTGCACTAGA GAAACTTGAATGCTCCATTCAGGCCTATCATTTTATTAAGTATGATTGACACAGCCCATG GGCCAGAACACACTCTACAAAATGACTAGGATAACAGAAAGAACGTGATCTCCTGATTAG AGAGGGTGGTTTTCCTCAATGGAACCAAATATAAAGAGGACTTGAACAAAAATGACAGAT ACAAACTATTTCTATCCTGAGTAGTAATCTCACACTTCATCCTATAGAGTCAACCACCAC AGATAGGAATTCCTTATTCTTTTTTTAATTTTTTTAAGACAGAGTCTCACTTTGTTGCCC AGGCTGGAGCGCAGTGGGGTGATCTCATCTCCCTGCAACCTCCGCCTCCTGGGTTCAAGC GATTCTTGTGCCTCAGCTTCCCAAGCAGCTGGGATTACAGGTGCCCGCCACCACGCCCAG CTAATTTTTGCATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCACGCTCGTCTCCAA CTCCTGACCTCAGGTAATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACATG AACCACCACGCCTGGCTGGAATACTTACTCTTGTCGGGAGATTGAACCACTAAAATGTTA GAGCAGAATTCATTATGCTGTGGTCACAGGGGTGTCTTGTCTGAGAACAAATACAATTCA GTCTTCTCTTTGGGGTTTTAGTATGTGTCAAACATAGGACTGGAAGTTTGCCCCTGTTCT TTTTTCTTTTGAAAGAACATCAGTTCATGCCTGAGGCATGAGTGACTGTGCATTTGAGAA TAGTTTTCCCTATTCTGTGGATACAGTCCCAGAGTTTTCAGGGAGTACACAGGTAGATTA GTTTGAAGCATTGACCTTTTATTTATTCCTTATTTCTCTTTCATCAAAACAAAACAGCAG CTGTGGGAGGAGAAATGAGAGGGCTTAAATGAAATTTAAAATAAGCTATATTATACAAAT ACTATCTCTGTATTGTTCTGACCCTGGTAAATATATTTCAAAACTTCAGATGACAAGGAT TAGAACACTCATTAAAGATGCTATTCTTCAGAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000587 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000587.2, NP_000578.2 |
| RefSeq Size | 4034 bp |
| RefSeq ORF | 2532 bp |
| Locus ID | 730 |
| UniProt ID | P10643 |
| Domains | CCP, tsp_1, MACPF, ldl_recept_a, FIMAC |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus |
| Gene Summary | This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209562 | C7 (Myc-DDK-tagged)-Human complement component 7 (C7) |
CNY 6,176.00 |
|
| RC209562L3 | Lenti ORF clone of Human complement component 7 (C7), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC209562L4 | Lenti ORF clone of Human complement component 7 (C7), mGFP tagged |
CNY 9,030.00 |
|
| RG209562 | C7 (tGFP-tagged) - Human complement component 7 (C7) |
CNY 7,776.00 |
|
| SC119808 | C7 (untagged)-Human complement component 7 (C7) |
CNY 6,184.00 |
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