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Complement C7 (C7) (NM_000587) Human Untagged Clone
CAT＃: SC119808
C7 (untagged)-Human complement component 7 (C7)
CNY 6,184.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119808 sequence for NM_000587 edited (data generated by NextGen Sequencing)
ATGAAGGTGATAAGCTTATTCATTTTGGTGGGATTTATAGGAGAGTTCCAAAGTTTTTCA AGTGCCTCCTCTCCAGTCAACTGCCAGTGGGACTTCTATGCCCCTTGGTCAGAATGCAAT GGCTGTACCAAGACTCAGACTCGCAGGCGGTCAGTTGCTGTGTATGGGCAGTATGGAGGC CAGCCTTGTGTTGGAAATGCTTTTGAAACACAGTCCTGTGAACCTACAAGAGGATGTCCA ACAGAGGAGGGATGTGGAGAGCGTTTCAGGTGCTTTTCAGGTCAGTGCATCAGCAAATCA TTGGTTTGCAATGGGGATTCTGACTGTGATGAAGACAGTGCTGATGAAGACAGATGTGAG GACTCAGAAAGGAGACCTTCCTGTGATATCGATAAACCTCCTCCTAACATAGAACTTACT GGAAATGGTTACAATGAACTCACTGGCCAGTTTAGGAACAGAGTCATCAATANCAAAAGT TTTGGTGGTCAATGTAGAAAGGTGTTTAGTGGGGATGGAAAAGATTTCTACAGGCTGAGT GGAAATGTCCTGTCCTATACATTCCAGGTGAAAATAAATAATGATTTTAATTATGAATTT TACAATAGTACTTGGTCTTATGTAAAACATACGTCGACAGAACACACATCATCTAGTCGG AAGCGCTCCTTTTTTAGATCTTCATCATCTTCTTCACGCAGTTATACTTCACATACCAAT GAAATCCATAAAGGAAAGAGTTACCAACTGCTGGTTGTTGAGAACACTGTTGAAGTGGCT CAGTTCATTAATAACAATCCAGAATTTTTACAACTTGCTGAGCCATTCTGGAAGGAGCTT TCCCACCTCCCCTCTCTGTATGACTACAGTGCCTACCGAAGATTAATCGACCAGTACGGG ACACATTATCTGCAATCTGGGTCGTTAGGAGGAGAATACAGAGTTCTATTTTATGTGGAC TCAGAAAAATTAAAACAAAATGATTTTAATTCAGTCGAAGAAAAGAAATGTAAATCCTCA GGTTGGCATTTTGTCGTTAAATTTTCAAGTCATGGATGCAAGGAACTGGAAAACGCTTTA AAAGCTGCTTCAGGAACCCAGAACAATGTATTGCGAGGAGAACCGTTCATCAGAGGGGGA GGTGCAGGCTTCATATCTGGCCTTACTTACCTAGAGCTGGACAATCCTGCTGGAAACAAA AGGCGATATTCTGCCTGGGCAGAATCTGTGACTAATCTTCCTCAAGTCATAAAACAAAAG CTGACACCTTTATATGAGCTGGTAAAGGAAGTACCTTGTGCCTCTGTGAAAAAACTATAC CTGAAATGGGCTCTTGAAGAGTATCTGGATGAATTTGACCCCTGTCATTGCCGGCCTTGT CAAAATGGTGGTTTGGCTACTGTTGAGGGGACCCATTGTCTGTGCCATTGCAAACCGTAC ACATTTGGTGCGGCGTGTGAGCAAGGAGTCCTCGTAGGGAATCAAGCAGGAGGGGTTGAT GGAGGTTGGAGTTGCTGGTCCTCTTGGAGCCCCTGTGTCCAAGGGAAGAAAACAAGAAGC CGTGAATGCAATAACCCACCTCCCAGTGGGGGTGGGAGATCCTGCGTTGGAGAAACGACA GAAAGCACACAATGCGAAGATGAGGAGCTGGAGCACTTGAGGTTGCTTGAACCACATTGC TTTCCTTTGTCCTTGGTTCCAACAGAATTCTGTCCATCACCTCCTGCCTTGAAAGATGGA TTTGTTCAAGATGAAGGTACAATGTTTCCTGTGGGGAAAAATGTAGTGTACACTTGCAAT GAAGGATACTCTCTTATTGGAAACCCAGTGGCCAGATGTGGAGAAGATTTACGGTGGCTT GTTGGGGAAATGCATTGTCAGAAAATTGCCTGTGTTCTACCTGTACTGATGGATGGCATA CAGAGTCACCCCCAAAAACCTTTCTACACAGTTGGTGAGAAGGTGACTGTTTCCTGTTCA GGTGGCATGTCCTTAGAAGGTCCTTCAGCATTTCTCTGTGGCTCCAGCCTTAAGTGGAGT CCTGAGATGAAGAATGCCCGCTGTGTACAAAAAGAAAATCCGTTAACACAGGCAGTGCCT AAATGTCAGCGCTGGGAGAAACTGCAGAATTCAAGATGTGTTTGTAAAATGCCCTACGAA TGTGGACCTTCCTTGGATGTATGTGCTCAAGATGAGAGAAGCAAAAGGATACTGCCTCTG ACAGTTTGCAAGATGCATGTTCTCCACTGTCAGGGTAGAAATTACACCCTTACTGGTAGG GACAGCTGTACTCTGCCTGCCTCAGCTGAGAAAGCTTGTGGTGCCTGCCCACTGTGGGGA AAATGTGATGCTGAGAGCAGCAAATGTGTCTGCCGAGAAGCATCGGAGTGCGAGGAAGAA GGGTTTAGCATTTGTGTGGAAGTGAACGGCAAGGAGCAGACGATGTCTGAGTGTGAGGCG GGCGCTCTGAGATGCAGAGGGCAGAGCATCTCTGTCACCAGCATAAGGCCTTGTGCTGCG GAAACCCAGTAG Clone variation with respect to NM_000587.2 473 c=>n;1166 g=>c;1692 t=>c >OriGene 5' read for NM_000587 unedited
NAAGCGTTCAAATATAGTCATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGGAGA GAGGCAGGCAGCCTGCTGGGCTCTTCCTGCTGTTGAAAACTTACCCGGCCCTTACAGAGG AAATCTTCCTCCTCTCTTCTGCCCTGAATGTTTTCCCAAACATGAAGGTGATAAGCTTAT TCATTTTGGTGGGATTTATAGGAGAGTTCCAAAGTTTTTCAAGTGCCTCCTCTCCAGTCA ACTGCCAGTGGGACTTCTATGCCCCTTGGTCAGAATGCAATGGCTGTACCAAGACTCAGA CTCGCAGGCGGTCAGTTGCTGTGTATGGGCAGTATGGAGGCCAGCCTTGTGTTGGAAATG CTTTTGAAACACAGTCCTGTGAACCTACAAGAGGATGTCCAACAGAGGAGGGATGTGGAG AGCGTTTCAGGTGCTTTTCAGGTCAGTGCATCAGCAAATCATTGGTTTGCAATGGGGATT CTGACTGTGATGAAGACAGTGCTGATGAAGACAGATGTGAGGACTCAGAAAGGAGACCTT CCTGTGATATCGATAAACCTCCTCCTAACATAGAACTTACTGGAAATGGTTACAATGAAC TCACTGGCCAGTTTAGGAACAGAGTCATCAATACCAAAAGTTTTGGTGGTCAATGTAGAA AGGTGTTTAGTGNGGATGGAAAAGATTTCTACAGGCTGAGTGGAAATGTCCTGTCCTATA CATTCCANGTGAAAATAAATAATGATTTTAATTATGAATNNTACAATAGTACTTGGTCTT ATGTAAAACATACGTCGACAGAACACACATCANTCTAGTCGAAGCGCTCCCTTNTTAGAT CTTCATCATCTTCTTCACGCAGTATACTTCACATACCAATGAAATCCCATAAGGAAAGAG TNACCCACTGNNCTGGTGTG >OriGene 3' read for NM_000587 unedited
ACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAGAAAGCATCTTTA ATGAGTGTTCTAATCCTTGTCATCTGAAGTTTTGAAATATATTTACCAGGGTCAGAACAA TACAGAGATAGTATTTGTATAATATAGCTTATTTTAAATTTCATTTAAGCCCTCTCATTT CTCCTCCCACAGCTGCTGTTTTGTTTTGATGAAAGAGAAATAAGGAATAAATAAAAGGTC AATGCTTCAAACTAATCTACCTGTGTACTCCCTGAAAACTCTGGGACTGTATCCACAGAA TAGGGAAAACTATTCTCAAATGCACAGTCACTCATGCCTCAGGCATGAACTGATGTTCTT TCAAAAGAAAAAAGAACAGGGGCAAACTTCCAGTCCTATGTTTGACACATACTAAAACCC CAAAGAGAAGACTGAATTGTATTTGTTCTCAGACAAGACACCCCTGTGACCACAGCATAA TGAATTCTGCTCTAACATTTTAGTGGCTCAATCTCCCGACAAGAGTAAGTATTCCAGCCA GGCGTGGTGGTTCATGTCTGTAATCCCACCACTTTGGGAGGCCAATGCAGGCGGATTACC TGAGGCCAGGAGTTGGAGACCAACGTGGCCAACATGGTGAAACCCCCTTTCTACTAAAAA TGCAAACAATACCCGGGCCGTGGGGGCGGCACCTTGTATCCCCCCTGCTCGTGGACCTCA CGCCACACAACCCCTTGACCCCCGAAAGCCGAAGCTTGCACGGACAACCAAATACCCCCC TTGCCCTCCCCCCTGGGCCACACACGGGCAACTCTCGTTCTCAAAAACATCCAAAAAAAT TAGCCCCTCCCATCTGCGCCGCCCCCCCTCCAAGAACCACTCTCCCCTCTCCTTCGGCAC CACAGTTCGTCCCCGTCCTTTTTTCCAGTCCCTCTCCTCTGCCCCCCCTCACCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000587 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000587.2, NP_000578.2 |
| RefSeq Size | 4034 bp |
| RefSeq ORF | 2532 bp |
| Locus ID | 730 |
| UniProt ID | P10643 |
| Domains | CCP, tsp_1, MACPF, ldl_recept_a, FIMAC |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus |
| Gene Summary | This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209562 | C7 (Myc-DDK-tagged)-Human complement component 7 (C7) |
CNY 6,176.00 |
|
| RC209562L3 | Lenti ORF clone of Human complement component 7 (C7), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC209562L4 | Lenti ORF clone of Human complement component 7 (C7), mGFP tagged |
CNY 9,030.00 |
|
| RG209562 | C7 (tGFP-tagged) - Human complement component 7 (C7) |
CNY 7,776.00 |
|
| SC322733 | C7 (untagged)-Human complement component 7 (C7) |
CNY 6,184.00 |
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