LRRC25 (NM_145256) Human Untagged Clone
CAT#: SC321936
LRRC25 (untagged)-Human leucine rich repeat containing 25 (LRRC25)
CNY 2,400.00
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | MAPA |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for NM_145256.2
GTAGGTTGCTTGAATGGGGGGCACCCTGGCATGGACGCTGCTGTTGCCGCTGCTGCTGCG
GGAGTCAGACAGCCTAGAACCGTCGTGCACCGTGTCCTCCGCGGATGTGGACTGGAACGC GGAGTTCAGTGCCACGTGCCTGAATTTCAGTGGCCTCAGCCTGAGCCTGCCTCACAACCA GTCTCTGCGGGCCAGCAACGTGATTCTCCTTGACCTGTCTGGGAACGGCCTGCGAGAGCT TCCAGTGACCTTCTTTGCCCACCTGCAGAAGCTTGAGGTCCTGAACGTGCTACGCAACCC CTTGTCTCGTGTGGATGGGGCGCTGGCCGCCCGCTGTGACCTTGACCTGCAGGCCGACTG CAACTGTGCCCTGGAGTCCTGGCACGACATCCGCCGAGACAACTGCTCTGGCCAGAAGCC TCTGCTCTGCTGGGACACAACCAGCTCCCAGCACAACCTCTCTGCCTTCCTGGAGGTCAG CTGCGCCCCTGGCCTGGCCTCTGCAACTATCGGGGCAGTGGTGGTCAGCGGGTGCCTGCT TCTTGGACTTGCCATCGCTGGCCCTGTGCTGGCCTGGAGACTCTGGCGATGCCGAGTGGC CAGAAGCCGGGAGCTGAACAAACCCTGGGCTGCTCAGGATGGGCCCAAGCCCGGTTTAGG CTTGCAGCCACGGTACGGCAGCCGGAGCGCCCCCAAGCCCCAAGTGGCCGTGCCATCCTG CCCCTCCACTCCCGACTATGAGAACATGTTTGTGGGCCAGCCAGCAGCCGAGCACCAGTG GGATGAACAAGGGGCTCACCCTTCAGAGGACAATGACTTTTACATCAACTACAAGGACAT CGACCTGGCTTCCCAGCCTGTCTACTGTAACCTGCAGTCACTGGGCCAGGCCTCAATGGA TGAAGAGGAGTACGTGATCCCCGGGCACTGAGCCTAAGATGTCCTAACCTCCACCCAGAA CCCCTTCAGTCCCTGCTGGGTGACTCAGGGCGTCCTAACTCCTCCATGGCCTCAGTTTCC CCATCTGAAGAATGGGGACAGGAAAGGATTGTCCTTGAGGCCCCAGGAAGCTCTGCCGCC CCCTCCCTGTCCCTCATGCCGCTCCTCAGCTCCCTCAGCTCCTAGAGGGGGAAGAGGAGA GACCCCCAACAAGGGGACAGGAGGGTCACTGTGCCAATCCTGTCATCACCCTCCTGTGGA TGTACAGGCAGTGCTCAATAAATGCTTCGAGGCTGATGAGGCTGCTGGCTCAGGGTGCGT GGGTTCCTCAAGGTGGGGATTTCTGAGTTCTAAGACCAAGTCTCCATCTGAGACTCCCAA ATTGCTCCCCACCTCCCATCCCTGTTTTTTTTTGTTGTTGTTGTTTGTTTGTTTGTTTTT GAAACTGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAATGCTGCGATCTCAGCTCACTG CAACCTCCGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAT TACAGCACCCGCCACCATGCCGAGCTAATTTTTGTATTTATAATAGAGATGGGGTTTCGC CATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGCGATCTGCCCACCTCGGCCTCC TGAAGTGCTGGGATTACAGGCGTGGCCACCGCACCCAGGCACATTCCTCCCTTCTGCCCC TCTCAGGGCCCCTTCCCAGGTCCCTGATCTCCAGGCTTGGCCTCCAGAGCAGCCCACACC ACCCCCAAAATAAAAAAATGTATATATTCCTTTAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_145256 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_145256.2, NP_660299.2 |
RefSeq Size | 2430 bp |
RefSeq ORF | 918 bp |
Locus ID | 126364 |
UniProt ID | Q8N386 |
Domains | LRR |
Protein Families | Transmembrane |
Gene Summary | Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy (PubMed:29288164). Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC209911 | LRRC25 (Myc-DDK-tagged)-Human leucine rich repeat containing 25 (LRRC25) |
CNY 2,400.00 |
|
RC209911L3 | Lenti ORF clone of Human leucine rich repeat containing 25 (LRRC25), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC209911L4 | Lenti ORF clone of Human leucine rich repeat containing 25 (LRRC25), mGFP tagged |
CNY 5,890.00 |
|
RG209911 | LRRC25 (tGFP-tagged) - Human leucine rich repeat containing 25 (LRRC25) |
CNY 4,000.00 |
|
SC100131 | LRRC25 (untagged)-Human leucine rich repeat containing 25 (LRRC25) |
CNY 1,200.00 |