LRRC25 (NM_145256) Human Untagged Clone
CAT#: SC100131
LRRC25 (untagged)-Human leucine rich repeat containing 25 (LRRC25)
CNY 1,200.00
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | MAPA |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC100131 sequence for NM_145256 edited (data generated by NextGen Sequencing)
ATGGGGGGCACCCTGGCATGGACGCTGCTGTTGCCGCTGCTGCTGCGGGAGTCAGACAGC CTAGAACCGTCGTGCACCGTGTCCTCCGCGGATGTGGACTGGAACGCGGAGTTCAGTGCC ACGTGCCTGAATTTCAGTGGCCTCAGCCTGAGCCTGCCTCACAACCAGTCTCTGCGGGCC AGCAACGTGATTCTCCTTGACCTGTCTGGGAACGGCCTGCGAGAGCTTCCAGTGACCTTC TTTGCCCACCTGCAGAAGCTTGAGGTCCTGAACGTGCTACGCAACCCCTTGTCTCGTGTG GATGGGGCGCTGGCCGCCCGCTGTGACCTTGACCTGCAGGCCGACTGCAACTGTGCCCTG GAGTCCTGGCACGACATCCGCCGAGACAACTGCTCTGGCCAGAAGCCTCTGCTCTGCTGG GACACAACCAGCTCCCAGCACAACCTCTCTGCCTTCCTGGAGGTCAGCTGCGCCCCTGGC CTGGCCTCTGCAACTATCGGGGCAGTGGTGGTCAGCGGGTGCCTGCTTCTTGGACTTGCC ATCGCTGGCCCTGTGCTGGCCTGGAGACTCTGGCGATGCCGAGTGGCCAGAAGCCGGGAG CTGAACAAACCCTGGGCTGCTCAGGATGGGCCCAAGCCCGGTTTAGGCTTGCAGCCACGG TACGGCAGCCGGAGCGCCCCCAAGCCCCAAGTGGCCGTGCCATCCTGCCCCTCCACTCCC GACTATGAGAACATGTTTGTGGGCCAGCCAGCAGCCGAGCACCAGTGGGATGAACAAGGG GCTCACCCTTCAGAGGACAATGACTTTTACATCAACTACAAGGACATCGACCTGGCTTCC CAGCCTGTCTACTGTAACCTGCAGTCACTGGGCCAGGCCTCAATGGATGAAGAGGAGTAC GTGATCCCCGGGCACTGA Clone variation with respect to NM_145256.2 880 c=>t >OriGene 5' read for NM_145256 unedited
GGAATTTGTAAACGACTTACTATAGGGNNCGGCCGCGNNAATTCGGCACGAGGGAACGCC AGCGACCCCAGCAGCGCTGCGGACGGTGCTGGCCGTGGCCGCTGCGGCCCCCGTGTCCAG GTGGGCCAGGACGCAGCCTCTGGGCGCCGTCGCTTTTCCAGCATCGCAGAGGCAAAAGCG TGGCAGTGGGACCCAAAAGGTTGCTTGAATGGGGGGCACCCTGGCATGGACGCTGCTGTT GCCGCTGCTGCTGCGGGAGTCAGACAGCCTAGAACCGTCGTGCACCGTGTCCTCCGCGGA TGTGGACTGGAACGCGGAGTTCAGTGCCACGTGCCTGAATTTCAGTGGCCTCAGCCTGAG CCTGCCTCACAACCAGTCTCTGCGGGCCAGCAACGTGATTCTCCTTGACCTGTCTGGGAA CGGCCTGCGAGAGCTTCCAGTGACCTTCTTTGCCCACCTGCAGAAGCTTGAGGTCCTGAA CGTGCTACGCAACCCCTTGTCTCGTGTGGATGGGGCGCTGGCCGCCCGCTGTGACCTTGA CCTGCAGGCCGACTGCAACTGTGCCCTGGAGTCCTGGCACGACATCCGCCGAGACAACTG CTCTGGCCAGAAGCCTCTGCTCTGCTGGGACACAACCAGCTCCCAGCACAACCTCTCTGC CTTCCTGGAGGTCAGCTGCGCCCCTGGCCTGGCCTCTGCAACTATCGGGGCAGTGGTGGT CAGCGGGTGCCTGCTTCTTGGACTTGCCATCGCTGGCCCTGTGCTGGCCTGGAGACTCTG GCGATGCCGAGTGGCCAGAAGCCGGGAGCTGAACANACCCTGGGCTGCTCANGATGGGCC CAAAGCCCGGTTTAAGCTTGCAGCCACGGTACGGCAGCCGGAGCGCCCNCAGCCCCAGTG GCCGTGCCATCTGCCCTCCACTCCCGATATGAGAACATGTTGTGGCCANCAGCAGCGAGC ACAGTGGATGAACAGGGCTCACCTTCAGAGACA |
Restriction Sites | NotI-NotI |
ACCN | NM_145256 |
Insert Size | 1500 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_145256.1, NP_660299.1 |
RefSeq Size | 1963 bp |
RefSeq ORF | 303 bp |
Locus ID | 126364 |
UniProt ID | Q8N386 |
Domains | LRR |
Protein Families | Transmembrane |
Gene Summary | Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy (PubMed:29288164). Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
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RC209911 | LRRC25 (Myc-DDK-tagged)-Human leucine rich repeat containing 25 (LRRC25) |
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RC209911L3 | Lenti ORF clone of Human leucine rich repeat containing 25 (LRRC25), Myc-DDK-tagged |
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RC209911L4 | Lenti ORF clone of Human leucine rich repeat containing 25 (LRRC25), mGFP tagged |
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RG209911 | LRRC25 (tGFP-tagged) - Human leucine rich repeat containing 25 (LRRC25) |
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SC321936 | LRRC25 (untagged)-Human leucine rich repeat containing 25 (LRRC25) |
CNY 2,400.00 |