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TDO2 (NM_005651) Human Untagged Clone
CAT＃: SC321049
TDO2 (untagged)-Human tryptophan 2,3-dioxygenase (TDO2)
CN¥ 3,656.00
CN¥ 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HYPTRP; TDO; TO; TPH2; TRPO |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_005651.1
AGGTCAATGATAGCATCTGCCTAGAGTCAAACCTCCGTGCTTCTCAGACAGTGCCTTTTC
ACCATGAGTGGGTGCCCATTTTTAGGAAACAACTTTGGATATACTTTTAAAAAACTCCCC GTAGAAGGCAGCGAAGAAGACAAATCACAAACTGGTGTGAATAGAGCCAGCAAAGGAGGT CTTATCTATGGGAACTACCTGCATTTGGAAAAAGTTTTGAATGCACAAGAACTGCAAAGT GAAACAAAAGGAAATAAAATCCATGATGAACATCTTTTTATCATAACTCATCAAGCTTAT GAACTCTGGTTTAAGCAAATCCTCTGGGAGTTGGATTCTGTTCGAGAGATCTTTCAGAAT GGCCATGTCAGAGATGAAAGGAACATGCTTAAGGTTGTTTCTCGGATGCACCGAGTGTCA GTGATCCTGAAACTGCTGGTGCAGCAGTTTTCCATTCTGGAGACGATGACAGCCTTGGAC TTCAATGACTTCAGAGAGTACTTATCTCCAGCATCAGGCTTCCAGAGTTTGCAATTCCGA CTATTAGAAAACAAGATAGGTGTTCTTCAGAACATGAGAGTCCCTTATAACAGAAGACAT TATCGTGATAACTTCAAAGGAGAAGAAAATGAACTGCTACTTAAATCTGAGCAGGAAAAG ACACTTCTGGAATTAGTGGAGGCATGGCTGGAAAGAACTCCAGGTTTAGAGCCACATGGA TTTAACTTCTGGGGAAAGCTTGAAAAAAATATCACCAGAGGCCTGGAAGAGGAATTCATA AGGATTCAGGCTAAAGAAGAGTCTGAAGAAAAAGAGGAACAGGTGGCTGAATTTCAGAAG CAAAAAGAGGTGCTACTGTCCTTATTTGATGAGAAACGTCATGAACATCTCCTTAGTAAA GGTGAAAGACGGCTGTCATACAGAGCACTTCAGGGAGCATTGATGATATATTTTTACAGG GAAGAGCCTAGGTTCCAGGTGCCTTTTCAGTTGCTGACTTCTCTTATGGACATAGATTCA CTGATGACCAAATGGAGATATAACCATGTGTGCATGGTGCACAGAATGCTGGGCAGCAAA GCTGGCACCGGTGGTTCCTCAGGCTATCACTACCTGCGATCAACTGTGAGTGATAGGTAC AAGGTATTTGTAGATTTATTTAATCTTTCAACATACCTGATTCCCCGACACTGGATACCG AAGATGAACCCAACCATTCACAAATTTCTATATACAGCAGAATACTGTGATAGCTCCTAC TTCAGCAGTGATGAATCAGATTAAAATCGTCTGCAAAATCTATGAAGAATACTGGTTTCA CAGCCTATTTTTTATTTTCTATGGATTTTCATAAATACAGTTTGAATATATGCATGCATA TATTGTTCAGCACCACGATGCTCTGATTTAATTCTAGAAACAATTTGATTACCTCTTGTT TGTGACAAGACTAAGCATTAAGATGAGAAAGAATACATTTAAATAGTAACATTGTACATA GGGTGTTTTCCTATTAAAAATTCAGTTTCCCCTGAGACTTAATGTAACCACTTAATGTAA TCACTATCTCATTGTTTCATCTTTATAAACTTGTAAACTTCATCTATTTCAAATATTTTA TGCAGTACATTATATTATTCTGTACAAAGGCTTTCAAACAAAATTTTTAAAATAATAAAG TATTAATCTCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_005651 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005651.1, NP_005642.1 |
| RefSeq Size | 1712 bp |
| RefSeq ORF | 1221 bp |
| Locus ID | 6999 |
| UniProt ID | P48775 |
| Domains | Trp_dioxygenase |
| Protein Pathways | Metabolic pathways, Tryptophan metabolism |
| Gene Summary | This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202777 | TDO2 (Myc-DDK-tagged)-Human tryptophan 2,3-dioxygenase (TDO2) |
CN¥ 3,656.00 |
|
| RC202777L1 | Lenti ORF clone of Human tryptophan 2,3-dioxygenase (TDO2), Myc-DDK-tagged |
CN¥ 6,056.00 |
|
| RC202777L2 | Lenti ORF clone of Human tryptophan 2,3-dioxygenase (TDO2), mGFP tagged |
CN¥ 6,056.00 |
|
| RC202777L3 | Lenti ORF clone of Human tryptophan 2,3-dioxygenase (TDO2), Myc-DDK-tagged |
CN¥ 6,056.00 |
|
| RC202777L4 | Lenti ORF clone of Human tryptophan 2,3-dioxygenase (TDO2), mGFP tagged |
CN¥ 5,890.00 |
|
| RG202777 | TDO2 (tGFP-tagged) - Human tryptophan 2,3-dioxygenase (TDO2) |
CN¥ 5,256.00 |
|
| SC116613 | TDO2 (untagged)-Human tryptophan 2,3-dioxygenase (TDO2) |
CN¥ 3,656.00 |
