TDO2 (NM_005651) Human Untagged Clone

CAT#: SC116613

TDO2 (untagged)-Human tryptophan 2,3-dioxygenase (TDO2)



  "NM_005651" in other vectors (7)

CNY 3,656.00

CNY 7,220.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
TDO2 mouse monoclonal antibody, clone OTI2A4 (formerly 2A4)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms HYPTRP; TDO; TO; TPH2; TRPO
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC116613 sequence for NM_005651 edited (data generated by NextGen Sequencing)
ATGAGTGGGTGCCCATTTTTAGGAAACAACTTTGGATATACTTTTAAAAAACTCCCCGTA
GAAGGCAGCGAAGAAGACAAATCACAAACTGGTGTGAATAGAGCCAGCAAAGGAGGTCTT
ATCTATGGGAACTACCTGCATTTGGAAAAAGTTTTGAATGCACAAGAACTGCAAAGTGAA
ACAAAAGGAAATAAAATCCATGATGAACATCTTTTTATCATAACTCATCAAGCTTATGAA
CTCTGGTTTAAGCAAATCCTCTGGGAGTTGGATTCTGTTCGAGAGATCTTTCAGAATGGC
CATGTCAGAGATGAAAGGAACATGCTTAAGGTTGTTTCTCGGATGCACCGAGTGTCAGTG
ATCCTGAAACTGCTGGTGCAGCAGTTTTCCATTCTGGAGACGATGACAGCCTTGGACTTC
AATGACTTCAGAGAGTACTTATCTCCAGCATCAGGCTTCCAGAGTTTGCAATTCCGACTA
TTAGAAAACAAGATAGGTGTTCTTCAGAACATGAGAGTCCCTTATAACAGAAGACATTAT
CGTGATAACTTCAAAGGAGAAGAAAATGAACTGCTACTTAAATCTGAGCAGGAAAAGACA
CTTCTGGAATTAGTGGAGGCATGGCTGGAAAGAACTCCAGGTTTAGAGCCACATGGATTT
AACTTCTGGGGAAAGCTTGAAAAAAATATCACCAGAGGCCTGGAAGAGGAATTCATAAGG
ATTCAGGCTAAAGAAGAGTCTGAAGAAAAAGAGGAACAGGTGGCTGAATTTCAGAAGCAA
AAAGAGGTGCTACTGTCCTTATTTGATGAGAAACGTCATGAACATCTCCTTAGTAAAGGT
GAAAGACGGCTGTCATACAGAGCACTTCAGGGAGCATTGATGATATATTTTTACAGGGAA
GAGCCTAGGTTCCAGGTGCCTTTTCAGTTGCTGACTTCTCTTATGGACATAGATTCACTG
ATGACCAAATGGAGATATAACCATGTGTGCATGGTGCACAGAATGCTGGGCAGCAAAGCT
GGCACCGGTGGTTCCTCAGGCTATCACTACCTGCGATCAACTGTGAGTGATAGGTACAAG
GTATTTGTAGATTTATTTAATCTTTCAACATACCTGATTCCCCGACACTGGATACCGAAG
ATGAACCCAACCATTCACAAATTTCTATATACAGCAGAATACTGTGATAGCTCCTACTTC
AGCAGTGATGAATCAGATTAA

Clone variation with respect to NM_005651.2
>OriGene 5' read for NM_005651 unedited
NGGGCGTGTCAGAATTTGTATACGACTCATATAGGCGGCCGCGAAATTCGCACGAGCCTA
GAGTCAAACCTCCGTGCTTCTCAGACGTGCCTTTTCACCATGAGTGGGTGCCCATTTTTA
GGAAACAACTTTGGATATACTTTTAAAAAACTCCCCGTAGAAGGCAGCGAAGAAGACAAA
TCACAAACTGGTGTGAATAGAGCCAGCAAAGGAGGTCTTATCTATGGGAACTACCTGCAT
TTGGAAAAAGTTTTGAATGCACAAGAACTGCAAAGTGAAACAAAAGGAAATAAAATCCAT
GATGAACATCTTTTTATCATAACTCATCAAGCTTATGAACTCTGGTTTAAGCAAATCCTC
TGGGAGTTGGATTCTGTTCGAGAGATCTTTCAGAATGGCCATGTCAGAGATGAAAGGAAC
ATGCTTAAGGTTGTTTCTCGGATGCACCGAGTGTCAGTGATCCTGAAACTGCTGGTGCAG
CAGTTTTCCATTCTGGAGACGATGACAGCCTTGGACTTCAATGACTTCAGAGAGTACTTA
TCTCCAGCATCAGGCTTCCAGAGTTTGCAATTCCGACTATTAGAAAACAAGAATAGGTGT
TCTTCAGAACATGAGAGTCCCTTATAACAGAAGACATTATCGTGATAACTTCAAAGGAGA
AGAAAATGAACTGCTACTTAAATCTGAGCANGAAAAGACACTTCTGGAATTAGTGGANGC
ATGGCTGGAAAGAACTNCAGGTTTAGAGCCCATGGATTTAACTTCTGGGGAAAGCTTGAA
AAAATATCACCAGAGGCCTGNAAAGAGAANTCATTAGGATTCANNGCTAAGAAGAGTCTG
AAGAAAAGAGNAACAANGTGGNCTGATTTCAGAGCAANAAGAAGTGCTACTNGTCT
>OriGene 3' read for NM_005651 unedited
NCCCACGTTGAAGCGCGGTCCGCATGCTAGGTACAAGCCTGGGGTAGGGTCACATGGTAG
GGGCGCAAGAATTCAGACTTGAATATTTTAAAAATTTGTTCGAAAGCCTTAGTCCAGAAT
AATATAATGTACTGCATAAAAATTTGAAATAAATGAAGTTTACAAGTTTATAAAGATGAA
ACAATGAGATAGTGATTACATTAAGTGGTTACGTTAAGTCTCAGGGGAAACTGAATTTTT
AATAGGAAAACACCCTATGTACAATGTTACTATTTAAATGTATTCTTTCTACATCTAAAT
GCTAAGTCTTGCCGCAAACAAAAGGTAATCAAATTGTTTCTAGAATGTAAATCATAGCAT
CGTGGTGCTGAACAATATATGCATACATATTTTCAAACTGTATTTATGAAAATCCTTAGA
AAATAAAAAATAGGCTGTGAAACCAGGCTTCTTCCATAGATTTTGCAGACGATTTTAATC
GGATTCATCACTGCTGAAGTAGGAGCTATCACAGTCTTCAGCTGCATATAGAAATTAGAG
AATGGCTGGGTTCATCTTCGGTATCCAGTGTCGGGGAATCAGGTCTGTTGAAAGATTAAG
TCAGTCTACAGATACCTTGTACCGATCACTCACAGTTGATCGCAGGTAGTGATAGCCTGC
AGGACCACCGGAGCCATCTTTGCTGCCCCGCATTCTGTGCACCATGCACACATGGTTATA
TCTCCTTTGATCACCAGGAAAACCAGTGCCTCAGATAATCCGCCCCTGAAAAGGCGCCTG
AAACCTAGGCTGTTTCCTGGTAAAATGGTTCATTCATGCATCCTGGACTGCTCAGAATGA
CAGCCCTTCTTTACCCTTCCTAAAGAAAAGGTCATGACGTTACAAAACAAAAAAGGGACC
TGCCGC
Restriction Sites NotI-NotI     
ACCN NM_005651
Insert Size 1750 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_005651.1, NP_005642.1
RefSeq Size 1712 bp
RefSeq ORF 1221 bp
Locus ID 6999
UniProt ID P48775
Domains Trp_dioxygenase
Protein Pathways Metabolic pathways, Tryptophan metabolism
Gene Summary This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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