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SPHK2 (NM_020126) Human Untagged Clone
CAT＃: SC320762
SPHK2 (untagged)-Human sphingosine kinase 2 (SPHK2), transcript variant 1
CNY 4,880.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SK-2; SK 2; SPK-2; SPK 2 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_020126.3
CGACTGACTAGCCGGGCGATAACGGCAGAGAGCATAGAGCGCAGGAACAAGCGCAACGTC
CAAGAGGGAAGGGCCAGCACGTCGGGGGCCTCTCTGGCCCTACCCAGGCCGTGTTCTCGA TAGCTTTCCGGAAGAAAGGGATCTGGGAGCGAGATGCGTGTAGCTAGCACGATGCGTCGC GCGGTGACGCTCTGGCCCGACGCCGACGGCCTCTCAGTGGCTCCCGGAGGACCCGGCGGG CCCAGTGTTGGAGAGCTGAAGGTCAGGCCAGGACAGTGAGACCTGACTCCTTGCTCCTAC CAGCCTACTATGGCTTAAGACCCAGGGCCAGGGTCCCGTTGATGTAACAGAGCAGAGGAC CAGCAGATGAATGGACACCTTGAAGCAGAGGAGCAGCAGGACCAGAGGCCAGACCAGGAG CTGACCGGGAGCTGGGGCCACGGGCCTAGGAGCACCCTGGTCAGGGCTAAGGCCATGGCC CCGCCCCCACCGCCACTGGCTGCCAGCACCCCGCTCCTCCATGGCGAGTTTGGCTCCTAC CCAGCCCGAGGCCCACGCTTTGCCCTCACCCTTACATCGCAGGCCCTGCACATACAGCGG CTGCGCCCCAAACCTGAAGCCAGGCCCCGGGGTGGCCTGGTCCCGTTGGCCGAGGTCTCA GGCTGCTGCACCCTGCGAAGCCGCAGCCCCTCAGACTCAGCGGCCTACTTCTGCATCTAC ACCTACCCTCGGGGCCGGCGCGGGGCCCGGCGCAGAGCCACTCGCACCTTCCGGGCAGAT GGGGCCGCCACCTACGAAGAGAACCGTGCCGAGGCCCAGCGCTGGGCCACTGCCCTCACC TGTCTGCTCCGAGGACTGCCACTGCCCGGGGATGGGGAGATCACCCCTGACCTGCTACCT CGGCCGCCCCGGTTGCTTCTATTGGTCAATCCCTTTGGGGGTCGGGGCCTGGCCTGGCAG TGGTGTAAGAACCACGTGCTTCCCATGATCTCTGAAGCTGGGCTGTCCTTCAACCTCATC CAGACAGAACGACAGAACCACGCCCGGGAGCTGGTCCAGGGGCTGAGCCTGAGTGAGTGG GATGGCATCGTCACGGTCTCGGGAGACGGGCTGCTCCATGAGGTGCTGAACGGGCTCCTA GATCGCCCTGACTGGGAGGAAGCTGTGAAGATGCCTGTGGGCATCCTCCCCTGCGGCTCG GGCAACGCGCTGGCCGGAGCAGTGAACCAGCACGGGGGATTTGAGCCAGCCCTGGGCCTC GACCTGTTGCTCAACTGCTCACTGTTGCTGTGCCGGGGTGGTGGCCACCCACTGGACCTG CTCTCCGTGACGCTGGCCTCGGGCTCCCGCTGTTTCTCCTTCCTGTCTGTGGCCTGGGGC TTCGTGTCAGATGTGGATATCCAGAGCGAGCGCTTCAGGGCCTTGGGCAGTGCCCGCTTC ACACTGGGCACGGTGCTGGGCCTCGCCACACTGCACACCTACCGCGGACGCCTCTCCTAC CTCCCCGCCACTGTGGAACCTGCCTCGCCCACCCCTGCCCATAGCCTGCCTCGTGCCAAG TCGGAGCTGACCCTAACCCCAGACCCAGCCCCGCCCATGGCCCACTCACCCCTGCATCGT TCTGTGTCTGACCTGCCTCTTCCCCTGCCCCAGCCTGCCCTGGCCTCTCCTGGCTCGCCA GAACCCCTGCCCATCCTGTCCCTCAACGGTGGGGGCCCAGAGCTGGCTGGGGACTGGGGT GGGGCTGGGGATGCTCCGCTGTCCCCGGACCCACTGCTGTCTTCACCTCCTGGCTCTCCC AAGGCAGCTCTACACTCACCCGTCTCCGAAGGGGCCCCCGTAATTCCCCCATCCTCTGGG CTCCCACTTCCCACCCCTGATGCCCGGGTAGGGGCCTCCACCTGCGGCCCGCCCGACCAC CTGCTGCCTCCGCTGGGCACCCCGCTGCCCCCAGACTGGGTGACGCTGGAGGGGGACTTT GTGCTCATGTTGGCCATCTCGCCCAGCCACCTAGGCGCTGACCTGGTGGCAGCTCCGCAT GCGCGCTTCGACGACGGCCTGGTGCACCTGTGCTGGGTGCGTAGCGGCATCTCGCGGGCT GCGCTGCTGCGCCTTTTCTTGGCCATGGAGCGTGGTAGCCACTTCAGCCTGGGCTGTCCG CAGCTGGGCTACGCCGCGGCCCGTGCCTTCCGCCTAGAGCCGCTCACACCACGCGGCGTG CTCACAGTGGACGGGGAGCAGGTGGAGTATGGGCCGCTACAGGCACAGATGCACCCTGGC ATCGGTACACTGCTCACTGGGCCTCCTGGCTGCCCGGGGCGGGAGCCCTGAAACTAAACA AGCTTGGTACCCGCCGGGGGCGGGGCCTACATTCCAATGGGGCGGAGCCTGAGCTAGGGG GTGTGGCCTGGCTGCTAGAGTTGTGGTGGCAGGGGCCCTGGCCCCGTCTCAGGATTGCGC TCGCTTTCATGGGACCAGACGTGATGCTGGAAGGTGGGCGTCGTCACGGTTAAAGAGAAA TGGGCTCGTCCCGAGGGTAGTGCCTGATCAATGAGGGCGGGGCCTGGCGTCTGATCTGGG GCCGCCCTTACGGGGCAGGGCTCAGTCCTGACGCTTGCCACCTGCTCCTACCCGGCCAGG ATGGCTGAGGGCGGAGTCTATTTTACGCGTCGCCCAATGACAGGACCTGGAATGTACTGG CTGGGGTAGGCCTCAGTGAGTCGGCCGGTCAGGGCCCGCAGCCTCGCCCCATCCACTCCG GTGCCTCCATTTAGCTGGCCAATCAGCCCAGGAGGGGCAGGTTCCCCGGGGCCGGCGCTA GGATTTGCACTAATGTTCCTCTCCCCGCGGGTGGGGGCGGGGAAATTCATATCCCCTGTT CGTCTCATGCGCGTCCTCCGTCCCCAATCTAAAAAGCAATTGAAAAGGTCTATGCAATAA AGGCAGTCGCTTCATTCCTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_020126 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020126.3, NP_064511.2 |
| RefSeq Size | 3012 bp |
| RefSeq ORF | 1965 bp |
| Locus ID | 56848 |
| UniProt ID | Q9NRA0 |
| Domains | DAGKc |
| Protein Families | Druggable Genome |
| Protein Pathways | Calcium signaling pathway, Fc gamma R-mediated phagocytosis, Metabolic pathways, Sphingolipid metabolism, VEGF signaling pathway |
| Gene Summary | This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 3 both encode the same isoform (a). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203019 | SPHK2 (Myc-DDK-tagged)-Human sphingosine kinase 2 (SPHK2), transcript variant 1 |
CNY 7,304.00 |
|
| RC203019L1 | Lenti ORF clone of Human sphingosine kinase 2 (SPHK2), transcript variant 1, Myc-DDK-tagged |
CNY 9,704.00 |
|
| RC203019L2 | Lenti ORF clone of Human sphingosine kinase 2 (SPHK2), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RC203019L3 | Lenti ORF clone of Human sphingosine kinase 2 (SPHK2), transcript variant 1, Myc-DDK-tagged |
CNY 9,704.00 |
|
| RC203019L4 | Lenti ORF clone of Human sphingosine kinase 2 (SPHK2), transcript variant 1, mGFP tagged |
CNY 9,704.00 |
|
| RG203019 | SPHK2 (tGFP-tagged) - Human sphingosine kinase 2 (SPHK2), transcript variant 1 |
CNY 8,904.00 |
|
| SC113181 | SPHK2 (untagged)-Human sphingosine kinase 2 (SPHK2), transcript variant 1 |
CNY 4,880.00 |
