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CLC7 (CLCN7) (NM_001287) Human Untagged Clone
CAT＃: SC320367
CLCN7 (untagged)-Human chloride channel 7 (CLCN7), transcript variant 1
CNY 5,904.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLC-7; CLC7; HOD; OPTA2; OPTB4; PPP1R63 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_001287.3
CCGGCGCTTCCCGGCCGGTGTCGCTCCGCGGCGGGCCATGGCCAACGTCTCTAAGAAGGT
GTCCTGGTCCGGCCGGGACCGGGACGACGAGGAGGCGGCGCCGCTGCTGCGGAGGACGGC GCGGCCCGGCGGGGGGACGCCGCTGCTGAACGGGGCTGGGCCTGGGGCTGCGCGCCAGTC ACCACGTTCTGCGCTTTTCCGAGTCGGACATATGAGCAGCGTGGAGCTGGATGATGAACT TTTGGACCCGGATATGGACCCTCCACATCCCTTCCCCAAGGAGATCCCACACAACGAGAA GCTCCTGTCCCTCAAGTATGAGAGCTTGGACTATGACAACAGTGAGAACCAGCTGTTCCT GGAGGAGGAGCGGCGGATCAATCACACGGCCTTCCGGACGGTGGAGATCAAGCGCTGGGT CATCTGCGCCCTCATTGGGATCCTCACGGGCCTCGTGGCCTGCTTCATTGACATCGTGGT GGAAAACCTGGCTGGCCTCAAGTACAGGGTCATCAAGGGCAATATCGACAAGTTCACAGA GAAGGGCGGACTGTCCTTCTCCCTGTTGCTGTGGGCCACGCTGAACGCCGCCTTCGTGCT CGTGGGCTCTGTGATTGTGGCTTTCATAGAGCCGGTGGCTGCTGGCAGCGGAATCCCCCA GATCAAGTGCTTCCTCAACGGGGTGAAGATCCCCCACGTGGTGCGGCTCAAGACGTTGGT GATCAAAGTGTCCGGTGTGATCCTGTCCGTGGTCGGGGGCCTGGCCGTGGGAAAGGAAGG GCCGATGATCCACTCAGGTTCAGTGATTGCCGCCGGGATCTCTCAGGGAAGGTCAACGTC ACTGAAACGAGATTTCAAGATCTTCGAGTACTTCCGCAGAGACACAGAGAAGCGGGACTT CGTCTCCGCAGGGGCTGCGGCCGGAGTGTCAGCGGCGTTTGGAGCCCCCGTGGGTGGGGT CCTGTTCAGCTTGGAGGAGGGTGCGTCCTTCTGGAACCAGTTCCTGACCTGGAGGATCTT CTTTGCTTCCATGATCTCCACGTTCACCCTGAATTTTGTTCTGAGCATTTACCACGGGAA CATGTGGGACCTGTCCAGCCCAGGCCTCATCAACTTCGGAAGGTTTGACTCGGAGAAAAT GGCCTACACGATCCACGAGATCCCGGTCTTCATCGCCATGGGCGTGGTGGGCGGTGTGCT TGGAGCAGTGTTCAATGCCTTGAACTACTGGCTGACCATGTTTCGAATCAGGTACATCCA CCGGCCCTGCCTGCAGGTGATTGAGGCCGTGCTGGTGGCCGCCGTCACGGCCACAGTTGC CTTCGTGCTGATCTACTCGTCGCGGGATTGCCAGCCCCTGCAGGGGGGCTCCATGTCCTA CCCGCTGCAGCTCTTTTGTGCAGATGGCGAGTACAACTCCATGGCTGCGGCCTTCTTCAA CACCCCGGAGAAGAGCGTGGTGAGCCTCTTCCACGACCCGCCAGGCTCCTACAACCCCCT GACCCTCGGCCTGTTCACGCTGGTCTACTTCTTCCTGGCCTGCTGGACCTACGGGCTCAC GGTGTCTGCCGGGGTCTTCATCCCGTCCCTGCTCATCGGGGCTGCCTGGGGCCGGCTCTT TGGGATCTCCCTGTCCTACCTCACGGGGGCGGCGATCTGGGCGGACCCCGGCAAATACGC CCTGATGGGAGCTGCTGCCCAGCTGGGCGGGATTGTGCGGATGACACTGAGCCTGACCGT CATCATGATGGAGGCCACCAGCAACGTGACCTACGGCTTCCCCATCATGCTGGTGCTCAT GACCGCCAAGATCGTGGGCGACGTCTTCATTGAGGGCCTGTACGACATGCACATTCAGCT GCAGAGTGTGCCCTTCCTGCACTGGGAGGCCCCGGTCACCTCACACTCACTCACTGCCAG GGAGGTGATGAGCACACCAGTGACCTGCCTGAGGCGGCGTGAGAAGGTCGGCGTCATTGT GGACGTGCTGAGCGACACGGCGTCCAATCACAACGGCTTCCCCGTGGTGGAGCATGCCGA TGACACCCAGCCTGCCCGGCTCCAGGGCCTGATCCTGCGCTCCCAGCTCATCGTTCTCCT AAAGCACAAGGTGTTTGTGGAGCGGTCCAACCTGGGCCTGGTACAGCGGCGCCTGAGGCT GAAGGACTTCCGAGACGCCTACCCGCGCTTCCCACCCATCCAGTCCATCCACGTGTCCCA GGACGAGCGGGAGTGCACCATGGACCTCTCCGAGTTCATGAACCCCTCCCCCTACACGGT GCCCCAGGAGGCGTCGCTCCCACGGGTGTTCAAGCTGTTCCGGGCCCTGGGCCTGCGGCA CCTGGTGGTGGTGGACAACCGCAATCAGGTTGTCGGGTTGGTGACCAGGAAGGACCTCGC CAGGTACCGCCTGGGAAAGAGAGGCTTGGAGGAGCTCTCGCTGGCCCAGACGTGAGGCCC AGCCCTGCCCATAATGGGCACTGGCGCTGGCACCCCGGCCCTTCTGCATTTCCTCCCGGA GTCACTGGTTTCTCGGCCCAAACCATGCTCCCCAGCAGTGGCAATGGCGAGCACCCTGCA GCTGGGCGGGCAGGCGGCAGGCGCGGAACTGACCCTCTCGCGGGACTGACCCTGTTGTGG GCAGTGGTCTCCCCCCTTGGCGCCTCCTTGCGCAGGCCCAGCCTCCACTCTCCTCGTCTA GGTTTCTTTACCTCCAGGGATCAGCTGTGTGTGTGTGACCTCCCTACCGGGCTATCGGCC TCTTGGGAGCCAGCGGCAGGGCCGGCACCTGCGTGCCTGTGCCCGTGTGCGTGAGACAGA GCCCTTGCCCCTGCTGCTGCCCCGAGGGCTGCCCTGCCCTGGAAGGGCCCCTCTGCCTCC ACACCAGTGGAGTCTTCGAGACTTGGGAGCTGCTTGGCCTCATTTTCAGCCATGAGCAGA CGGCCTGTGGTCCCTGGGCCTGAGGCACGGACTCGTAGCACCAGGGTTTGGAGGCTGCGA CCGCCCCGGAGAGCAGCTTCACACTGGCGCCACAGAGGAGCCCCACGTGCACTCCCCGGC CTGCATCCGGCTTGGGTACACGGGCCCAGAGGACTGGGGTGACTCACGGGCCCTGTGCTG TGATGTTGAGAGCTGAGAAAAACCTCCAAGGCCCTGAGCCCCATGCCCAGCCCTGCCTTG GTCCCCCAACCCCCAGAGCTTGGAGTCTGGGCCCCACACCCAGCCCTGCCTTGGTCCCTG AGCCTCAGAGCGTGGAATTGCTGCCCTGTGGACACTGGCTGGGAAGGCAGGTCTTCCCCT AGCACATGGGGACCCCGGCCTCGAGGGTGACCTCCCTACCTTGCCCCTGCCAGCCACCAA GCGCAGGTGCAGCGGGGGCCAGACTCCTGCCGGCCTCAGAGGACACCTGGCCCAGCACAG GCAGCTAGAAGGGCCGGTGGGCACCGGGGCCGGGAAGCCCCCACCTCACCACCTGAGGGC CCCTGGGAGGCTCCTCTGGCCTGGCTGGGCTGGGTCTGGGGCCGCCACAGGCCCCTCACG GGGCGGCAGAGGCAACTTCAGTGTCCCTGTTAGAGCAACACGGGTCCCTCCGTGGGGGGC TGGGTGCGGCCCCCTGCCGTGTATTTCCTCCCCAGGGAGTGGGGCCTCCCCGGGAGCTGA CGCCACCACCCTGCTTAGCCCTCACAGGGCCCCAAGGTGTCCGAGTGTGTTGGGTCTGAA CGCGAAATAAAGAAATCCTCTCAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001287 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001287.3, NP_001278.1 |
| RefSeq Size | 3760 bp |
| RefSeq ORF | 2418 bp |
| Locus ID | 1186 |
| UniProt ID | P51798 |
| Domains | CBS, voltage_CLC |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
| Gene Summary | The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203450 | CLCN7 (Myc-DDK-tagged)-Human chloride channel 7 (CLCN7), transcript variant 1 |
CNY 8,840.00 |
|
| RC203450L1 | Lenti ORF clone of Human chloride channel 7 (CLCN7), transcript variant 1, Myc-DDK-tagged |
CNY 11,240.00 |
|
| RC203450L2 | Lenti ORF clone of Human chloride channel 7 (CLCN7), transcript variant 1, mGFP tagged |
CNY 7,700.00 |
|
| RC203450L3 | Lenti ORF clone of Human chloride channel 7 (CLCN7), transcript variant 1, Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC203450L4 | Lenti ORF clone of Human chloride channel 7 (CLCN7), transcript variant 1, mGFP tagged |
CNY 7,700.00 |
|
| RG203450 | CLCN7 (tGFP-tagged) - Human chloride channel 7 (CLCN7), transcript variant 1 |
CNY 10,440.00 |
|
| SC108053 | CLCN7 (untagged)-Human chloride channel 7 (CLCN7), transcript variant 1 |
CNY 5,904.00 |
