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SENP6 (NM_015571) Human Untagged Clone
CAT＃: SC315191
SENP6 (untagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1
CNY 21,470.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SSP1; SUSP1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC315191 representing NM_015571.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGGCCGGCAAGAGCGGCGGTAGCGCAGGGGAGATTACTTTTCTGGAAGCTTTGGCTAGATCAGAG TCTAAGAGAGATGGAGGTTTTAAAAATAATTGGAGCTTTGATCATGAAGAAGAAAGTGAAGGAGATACA GATAAAGATGGGACAAATCTGCTCAGTGTGGATGAAGATGAGGATTCTGAAACCTCAAAAGGAAAAAAG TTAAATCGTCGATCTGAAATTGTTGCTAATAGCTCTGGTGAATTCATCTTGAAGACATATGTAAGACGA AACAAGTCTGAAAGTTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAG AAATTGAGTGAAAATACGCAAAATACGTCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCAT CATGCTCATGCACAGATACCAGTAGTAAAAACAGCAGCCCAAAGCAGTCTGGACCGAAAAGAAAGGAAA GAATACCCACCTCATGTCCAAAAAGTTGAAATTAATCCTGTAAGGTTAAGTCGGCTCCAAGGTGTTGAA CGTATAATGAAGAAAACAGAAGAGTCCGAATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAG AAACGACACTGTAGTACCTATCAGCCTACTCCTCCTCTATCTCCTGCTTCAAAAAAATGTTTAACCCAT TTAGAGGATTTGCAAAGAAATTGCAGACAAGCTATTACTTTGAATGAGTCTACTGGACCATTATTAAGA ACGTCAATTCATCAGAATTCTGGAGGACAGAAGTCACAAAACACAGGATTAACAACCAAGAAGTTTTAT GGCAACAATGTGGAAAAGGTTCCAATTGATATTATTGTGAATTGTGATGACAGTAAACACACTTATTTA CAGACTAATGGAAAAGTCATTTTACCTGGGGCAAAAATACCCAAAATCACAAACTTGAAAGAAAGGAAA ACAAGTTTGTCAGACCTAAATGATCCAATCATTTTGTCCAGTGATGATGATGATGACAACGACAGAACT AACAGAAGAGAAAGCATATCTCCTCAGCCTGCTGATTCAGCATGTTCTTCCCCTGCACCATCCACTGGA AAAGTAGAAGCAGCGCTAAATGAAAATACTTGCAGAGCAGAGCGTGAACTACGAAGCATTCCAGAAGAC TCAGAGTTAAATACAGTTACATTGCCAAGAAAAGCAAGAATGAAAGACCAGTTTGGCAATTCTATTATC AACACACCTCTGAAACGTCGTAAAGTGTTTTCTCAAGAACCTCCAGATGCTTTAGCTTTAAGCTGCCAA AGTTCCTTTGACAGTGTCATTTTAAACTGTCGAAGTATACGAGTAGGAACACTCTTCCGGCTGTTAATA GAGCCTGTAATTTTTTGTTTAGATTTTATCAAGATACAGCTAGACGAACCAGACCATGATCCTGTAGAG ATTATATTAAATACCTCTGATCTAACTAAATGTGAATGGTGTAATGTCCGAAAATTACCTGTAGTGTTT CTTCAAGCAATTCCAGCAGTTTATCAAAAGCTGAGCATCCAACTGCAAATGAATAAGGAGGATAAAGTT TGGAATGATTGTAAAGGAGTAAATAAATTAACAAATTTAGAAGAACAATATATAATTTTAATTTTTCAA AATGGCCTTGATCCTCCGGCAAATATGGTATTTGAAAGTATCATTAATGAAATTGGTATAAAGAATAAC ATCTCCAATTTTTTTGCGAAAATTCCCTTTGAAGAAGCTAATGGCAGACTTGTTGCCTGTACAAGAACC TATGAAGAGAGCATCAAAGGAAGTTGTGGGCAAAAGGAAAACAAAATTAAAACTGTATCATTTGAATCT AAAATACAACTTAGAAGCAAACAAGAATTTCAGTTTTTTGATGAAGAAGAAGAAACTGGAGAAAACCAC ACCATCTTCATTGGCCCAGTAGAAAAGTTGATAGTATATCCACCACCTCCAGCTAAGGGAGGCATCTCT GTTACCAATGAGGACCTGCACTGTCTAAATGAAGGAGAATTTTTAAATGATGTTATTATAGACTTTTAT TTGAAATACTTGGTGCTTGAAAAACTGAAGAAGGAAGACGCTGACCGAATTCATATATTCAGTTCTTTT TTCTATAAACGCCTTAATCAGAGAGAGAGGAGAAATCATGAAACAACTAATCTGTCAATACAGCAAAAA CGGCATGGGAGAGTAAAAACATGGACCCGGCACGTAGATATTTTTGAGAAGGATTTTATTTTTGTACCC CTTAATGAAGCTGCACACTGGTTTTTGGCTGTTGTTTGTTTCCCCGGTTTGGAAAAACCAAAGTATGAA CCTAATCCTCATTACCATGAAAATGCTGTCATACAGAAATGTTCAACTGTAGAGGACAGTTGTATTTCT TCTTCAGCCAGTGAAATGGAGAGTTGTTCACAAAACTCTTCTGCCAAGCCTGTAATTAAGAAGATGCTA AACAAAAAACATTGCATAGCTGTAATTGATTCCAATCCTGGGCAGGAAGAAAGTGACCCTCGTTATAAG AGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAATAAATCATACTGCGAGTGAAAATGAAGAATTC AATAAAGGAGAATCTACATCCCAGAAAGTTGCTGATAGGACTAAAAGTGAGAATGGCCTACAGAATGAA AGTTTAAGTTCCACACATCATACAGATGGCTTAAGCAAAATCAGACTAAACTATAGCGATGAATCACCT GAAGCTGGTAAAATGCTTGAAGATGAACTCGTCGACTTCTCAGAAGATCAGGATAACCAGGATGATAGC AGTGACGATGGATTCCTCGCTGATGACAACTGCAGTTCAGAAATAGGACAGTGGCATTTAAAGCCTACT ATCTGTAAACAACCTTGTATCCTACTTATGGACTCACTCCGAGGCCCTTCTCGGTCAAATGTTGTCAAA ATTTTAAGAGAGTATTTAGAAGTGGAATGGGAAGTTAAAAAAGGAAGCAAAAGAAGTTTTTCCAAAGAT GTTATGAAGGGCTCTAATCCAAAAGTACCACAGCAAAACAACTTCAGTGACTGTGGTGTATATGTATTG CAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTCAGTTTTGAACTACCTATGAATTTGGCAAACTGG TTTCCTCCACCAAGAATGAGAACAAAAAGAGAAGAAATCCGAAACATAATTCTGAAGCTACAGGAAGAT CAGAGCAAAGAGAAAAGAAAGCATAAGGACACTTACTCAACAGAAGCACCTTTAGGCGAAGGAACAGAA CAATATGTCAATAGTATCTCAGATTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_015571 |
| Insert Size | 3339 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015571.3 |
| RefSeq Size | 7046 bp |
| RefSeq ORF | 3339 bp |
| Locus ID | 26054 |
| UniProt ID | Q9GZR1 |
| Domains | Peptidase_C48 |
| Protein Families | Druggable Genome, Protease |
| MW | 126.1 kDa |
| Gene Summary | Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211809 | SENP6 (Myc-DDK-tagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1 |
CNY 7,744.00 |
|
| RC211809L1 | Lenti ORF clone of Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1, Myc-DDK-tagged |
CNY 10,144.00 |
|
| RC211809L2 | Lenti ORF clone of Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1, mGFP tagged |
CNY 13,020.00 |
|
| RC211809L3 | Lenti ORF clone of Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1, Myc-DDK-tagged |
CNY 13,020.00 |
|
| RC211809L4 | Lenti ORF clone of Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1, mGFP tagged |
CNY 13,020.00 |
|
| RG211809 | SENP6 (tGFP-tagged) - Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1 |
CNY 12,260.00 |
