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SENP6 (NM_015571) Human Tagged ORF Clone
CAT＃: RC211809
SENP6 (Myc-DDK-tagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1
ORF Plasmid: tGFP
"NM_015571" in other vectors (6)
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CNY 7,744.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | SSP1; SUSP1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC211809 representing NM_015571
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCCGGCAAGAGCGGCGGTAGCGCAGGGGAGATTACTTTTCTGGAAGCTTTGGCTAGATCAGAGT CTAAGAGAGATGGAGGTTTTAAAAATAATTGGAGCTTTGATCATGAAGAAGAAAGTGAAGGAGATACAGA TAAAGATGGGACAAATCTGCTCAGTGTGGATGAAGATGAGGATTCTGAAACCTCAAAAGGAAAAAAGTTA AATCGTCGATCTGAAATTGTTGCTAATAGCTCTGGTGAATTCATCTTGAAGACATATGTAAGACGAAACA AGTCTGAAAGTTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAGAAATT GAGTGAAAATATGCAAAATACGTCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCATCATGCT CATGCACAGATACCAGTAGTAAAAACAGCAGCCCAAAGCAGTCTGGACCGAAAAGAAAGGAAAGAATACC CACCTCATGTCCAAAAAGTTGAAATTAATCCTGTAAGGTTAAGTCGGCTCCAAGGTGTTGAACGTATAAT GAAGAAAACAGAAGAGTCCGAATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAGAAACGGCAC TGTAGTACCTATCAGCCTACTCCTCCTCTATCTCCTGCTTCAAAAAAATGTTTAACCCATTTAGAGGATT TGCAAAGAAATTGCAGACAAGCTATTACTTTGAATGAGTCTACTGGACCATTATTAAGAACGTCAATTCA TCAGAATTCTGGAGGACAGAAGTCACAAAACACAGGATTAACAACCAAGAAGTTTTATGGCAACAATGTG GAAAAGGTTCCAATTGATATTATTGTGAATTGTGATGACAGTAAACACACTTATTTACAGACTAATGGAA AAGTCATTTTACCTGGGGCAAAAATACCCAAAATCACAAACTTGAAAGAAAGGAAAACAAGTTTGTCAGA CCTAAATGATCCAATCATTTTGTCCAGTGATGATGATGATGACAACGACAGAACTAACAGAAGAGAAAGC ATATCTCCTCAGCCTGCTGATTCAGCATGTTCTTCCCCTGCACCATCCACTGGAAAAGTAGAAGCAGCAC TAAATGAAAATACTTGCAGAGCAGAGCGTGAACTACGAAGCATTCCAGAAGACTCAGAGTTAAATACAGT TACATTGCCAAGAAAAGCAAGAATGAAAGACCAGTTTGGCAATTCTATTATCAACACACCTCTGAAACGT CGTAAAGTGTTTTCTCAAGAACCTCCAGATGCTTTAGCTTTAAGCTGCCAAAGTTCCTTTGACAGTGTCA TTTTAAACTGTCGAAGTATACGAGTAGGAACACTCTTCCGGCTGTTAATAGAGCCTGTAATTTTTTGTTT AGATTTTATCAAGATACAGCTAGACGAACCAGACCATGATCCTGTAGAGATTATATTAAATACCTCTGAT CTAACTAAATGTGAATGGTGTAATGTCCGAAAATTACCTGTAGTGTTTCTTCAAGCAATTCCAGCAGTTT ATCAAAAGCTGAGCATCCAACTGCAAATGAATAAGGAGGATAAAGTTTGGAATGATTGTAAAGGAGTAAA TAAATTAACAAATTTAGAAGAACAATATATAATTTTAATTTTTCAAAATGGCCTTGATCCTCCGGCAAAT ATGGTATTTGAAAGTATCATTAATGAAATTGGTATAAAGAATAACATCTCCAATTTTTTTGCGAAAATTC CCTTTGAAGAAGCTAATGGCAGACTTGTTGCCTGTACAAGAACCTATGAAGAGAGCATCAAAGGAAGTTG TGGGCAAAAGGAAAACAAAATTAAAACTGTATCATTTGAATCTAAAATACAACTTAGAAGCAAACAAGAA TTTCAGTTTTTTGATGAAGAAGAAGAAACTGGAGAAAACCACACCATCTTCATTGGCCCAGTAGAAAAGT TGATAGTATATCCACCACCTCCAGCTAAGGGAGGCATCTCTGTTACCAATGAGGACCTGCACTGTCTAAA TGAAGGAGAATTTTTAAATGATGTTATTATAGACTTTTATTTGAAATACTTGGTGCTTGAAAAACTGAAG AAGGAAGACGCTGACCGAATTCATATATTCAGTTCTTTTTTCTATAAACGCCTTAATCAGAGAGAGAGGA GAAATCATGAAACAACTAATCTGTCAATACAGCAAAAACGGCATGGGAGAGTAAAAACATGGACCCGGCA CGTAGATATTTTTGAGAAGGATTTTATTTTTGTACCCCTTAATGAAGCTGCACACTGGTTTTTGGCTGTT GTTTGTTTCCCCGGTTTGGAAAAACCAAAGTATGAACCTAATCCTCATTACCATGAAAATGCTGTCATAC AGAAATGTTCAACTGTAGAGGACAGTTGTATTTCTTCTTCAGCCAGTGAAATGGAGAGTTGTTCACAAAA CTCTTCTGCCAAGCCTGTAATTAAGAAGATGCTAAACAAAAAACATTGCATAGCTGTAATTGATTCCAAT CCTGGGCAGGAAGAAAGTGACCCTCGTTATAAGAGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAA TAAATCATACTGCGAGTGAAAATGAAGAATTCAATAAAGGAGAATCTACATCCCAGAAAGTTGCTGATAG GACTAAAAGTGAGAATGGCCTACAGAATGAAAGTTTAAGTTCCACACATCATACAGATGGCTTAAGCAAA ATCAGACTAAACTATAGCGATGAATCACCTGAAGCTGGTAAAATGCTTGAAGATGAACTCGTCGACTTCT CAGAAGATCAGGATAACCAGGATGATAGCAGTGACGATGGATTCCTCGCTGATGACAACTGCAGTTCAGA AATAGGACAGTGGCATTTAAAGCCTACTATCTGTAAACAACCTTGTATCCTACTTATGGACTCACTCCGA GGCCCTTCTCGGTCAAATGTTGTCAAAATTTTAAGAGAGTATTTAGAAGTGGAATGGGAAGTTAAAAAAG GAAGCAAAAGAAGTTTTTCCAAAGATGTTATGAAGGGCTCTAATCCAAAAGTACCACAGCAAAACAACTT CAGTGACTGTGGTGTATATGTATTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTCAGTTTTGAA CTACCTATGAATTTGGCAAACTGGTTTCCTCCACCAAGAATGAGAACAAAAAGAGAAGAAATCCGAAACA TAATTCTGAAGCTACAGGAAGATCAGAGCAAAGAGAAAAGAAAGCATAAGGACACTTACTCAACAGAAGC ACCTTTAGGCGAAGGAACAGAACAATGTGTCAATAGTATCTCAGAT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC211809 representing NM_015571
Red=Cloning site Green=Tags(s) MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKL NRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENMQNTSLCSGTVVHGRRFHHA HAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRH CSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNV EKVPIDIIVNCDDSKHTYLQTNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRES ISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKR RKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSD LTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPAN MVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQE FQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLK KEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAV VCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSN PGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSK IRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLR GPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFE LPMNLANWFPPPRMRTKREEIRNIILKLQEDQSKEKRKHKDTYSTEAPLGEGTEQCVNSISD TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_015571 |
| ORF Size | 3336 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015571.1, NP_056386.1 |
| RefSeq Size | 4210 bp |
| RefSeq ORF | 3339 bp |
| Locus ID | 26054 |
| UniProt ID | Q9GZR1 |
| Domains | Peptidase_C48 |
| Protein Families | Druggable Genome, Protease |
| MW | 126 kDa |
| Gene Summary | Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211809L1 | Lenti ORF clone of Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1, Myc-DDK-tagged |
CNY 10,144.00 |
|
| RC211809L2 | Lenti ORF clone of Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1, mGFP tagged |
CNY 13,020.00 |
|
| RC211809L3 | Lenti ORF clone of Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1, Myc-DDK-tagged |
CNY 13,020.00 |
|
| RC211809L4 | Lenti ORF clone of Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1, mGFP tagged |
CNY 13,020.00 |
|
| RG211809 | SENP6 (tGFP-tagged) - Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1 |
CNY 12,260.00 |
|
| SC315191 | SENP6 (untagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 1 |
CNY 21,470.00 |
