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Beta TRCP (BTRC) (NM_003939) Human Untagged Clone
CAT＃: SC314040
BTRC (untagged)-Human beta-transducin repeat containing (BTRC), transcript variant 2
CNY 4,248.00
CNY 9,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BETA-TRCP; betaTrCP; bTrCP; bTrCP1; FBW1A; FBXW1; FBXW1A; FWD1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003939 edited
CCCCGGCGGAGAGCGGACCCAGTGGCCTCGGCGATTATGGACCCGGCCGAGGCGGTGCTG CAAGAGAAGGCACTCAAGTTTATGAATTCCTCAGAGAGAGAAGACTGTAATAATGGCGAA CCCCCTAGGAAGATAATACCAGAGAAGAATTCACTTAGACAGACATACAACAGCTGTGCC AGACTCTGCTTAAACCAAGAAACAGTATGTTTAGCAAGCACTGCTATGAAGACTGAGAAT TGTGTGGCCAAAACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGG AAACTCTCAGCAAGCTATGAAAAGGAAAAGGAACTGTGTGTCAAATACTTTGAGCAGTGG TCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATATCCCAAATGTGTCATTACCAA CATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTG CCAGCTCGGGGATTGGATCATATTGCTGAGAACATTCTGTCATACCTGGATGCCAAATCA CTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAGTGACCTCTGATGGCATGCTG TGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAA CGAAGAGGATGGGGACAGTATTTATTCAAAAACAAACCTCCTGACGGGAATGCTCCTCCC AACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAGACATTGAGACAATAGAATCT AATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGTGAAACAAGCAAA GGAGTTTACTGTTTACAGTATGATGATCAGAAAATAGTAAGCGGCCTTCGAGACAACACA ATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAATTCTCACAGGCCATACAGGT TCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCCACG GTCAGAGTGTGGGATGTAAATACAGGTGAAATGCTAAACACGTTGATTCACCATTGTGAA GCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGACCTGCTCCAAAGATCGTTCC ATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGA CACCGAGCTGCTGTCAATGTTGTAGACTTTGATGACAAGTACATTGTTTCTGCATCTGGG GATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAATTTGTAAGGACCTTAAATGGA CACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCT GACAACACTATCAGATTATGGGACATAGAATGTGGTGCATGTTTACGAGTGTTAGAAGGC CATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGAGGATAGTCAGTGGGGCCTAT GATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGG ACACTCTGTCTACGGACCCTTGTGGAGCATTCCGGAAGAGTTTTTCGACTACAGTTTGAT GAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCCTCATCTGGGACTTCCTAAAT GATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATACACCTACATCTCC AGATAAATAACCATACACTGACCTCATACTTGCCCAGGACCCATTAAAGTTGCGGTATTT AACGTATCTGCCAATACCAGGATGAGCAACAACAGTAACAATCAAACTACTGCCCAGTTT CCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTCTGCAG TCGGCCCAGGACGGTCTACTCAGCACAACTGACTGCTTCAGTGCTGCTATCAGAAGATGT CTTCTATCTTTTGTGAATGATTGGAACTTTTAAACCTCCCCTCCTCTCCTCCTTTCACCT CTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAGTGT TTTGCCAGAATCTCTCTTGCTTTGCCATTAAGCAGAAGAACTAGTTTCCCTGTATAGCCT GCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCTTCAAGCCCAGTGCCCAGTGT CTCCCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATATGCT TAGGAGGAGACAGAGTTCCCTCTGTATAGCCTCTGGGACAAGAAAAAGAAAACACAAGAA TGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTCTTTGTTTCTGTTCCTCTTCC CATCTACTCCCCTACGCCCCTTCAACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGAAAG TGTACGAAGAGAGTGTCCTCCTCTCACATGAGCCAGATCAGCCAGAAAATGCAACACTTG GAAGAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGGCCTTTGCTGCAAGTGACCCT GTGGCAACAGTGGATTCTCAGACATGATACTCTCATCATATTTGCAACTCTTCTCTCTCT TTCTTCCCCACACCCAAGAGGAGGATTGGTGGTAGGGGGCAGGCAGAGGGGGTGGGGAGA AGTTTCCTGGGCTCCATCAATGGCTGCATCTTTTCTGGACTCAGCAGTCTCCTTGATTCC ATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGTGTGTA ATAAAAAGCATTGTACTTCATCTTAAAAAAAAAAAAAAAAAAAACTCGAC |
| Restriction Sites | Please inquire |
| ACCN | NM_003939 |
| Insert Size | 2900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_003939.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003939.2, NP_003930.1 |
| RefSeq Size | 6038 bp |
| RefSeq ORF | 1710 bp |
| Locus ID | 8945 |
| UniProt ID | Q9Y297 |
| Domains | WD40, F-box |
| Protein Families | Druggable Genome |
| Protein Pathways | Hedgehog signaling pathway, Oocyte meiosis, Ubiquitin mediated proteolysis, Wnt signaling pathway |
| Gene Summary | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6. [provided by RefSeq, Mar 2012] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Sequence Note:. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214799 | BTRC (Myc-DDK-tagged)-Human beta-transducin repeat containing (BTRC), transcript variant 2 |
CNY 4,240.00 |
|
| RC214799L3 | Lenti-ORF clone of BTRC (Myc-DDK-tagged)-Human beta-transducin repeat containing (BTRC), transcript variant 2 |
CNY 6,940.00 |
|
| RC214799L4 | Lenti-ORF clone of BTRC (mGFP-tagged)-Human beta-transducin repeat containing (BTRC), transcript variant 2 |
CNY 6,940.00 |
|
| RG214799 | BTRC (tGFP-tagged) - Human beta-transducin repeat containing (BTRC), transcript variant 2 |
CNY 5,510.00 |
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