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BRCC45 (BRE) (NM_199192) Human Untagged Clone
CAT＃: SC310467
BRE (untagged)-Human brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 5
CN¥ 6,180.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BRCC4; BRCC45; BRE |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC310467 representing NM_199192.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTCCCCAGAAGTGGCCTTGAACCGAATATCTCCAATGCTCTCCCCTTTCATATCTAGCGTGGTCCGG AATGGAAAAGTGGGACTGGATGCTACAAACTGTTTGAGGATAACTGACTTAAAATCTGGCTGCACATCA TTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTGG GATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTC CTGCCAGACCCCTCAGCTTTGCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTT GTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATGTAGCCGCCTCCGGGAGAGCTCCCGCCTC ATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGCTGGGAAA AAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATC CCCACATACCTTCTCAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTT GAGGACACTGAAGCCACCCAGGTGTACCCCAAGCTGTACTTGTCACCTCGAATTGAGCATGCACTTGGA GGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTACGTTCCTCAAGTA TGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCT GCTTTTCTCAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTG CTGCTGATGTGGAAAGATTTTTGTTTTCTTGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAG CCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCTTTACTCCCAGGCCCAAAAA AATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAAAGAGAGAGCAACAGA GATGGGGAGGAATCCAGCTCTGCCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_199192 |
| Insert Size | 1131 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_199192.2 |
| RefSeq Size | 1876 bp |
| RefSeq ORF | 1131 bp |
| Locus ID | 9577 |
| UniProt ID | Q9NXR7 |
| Protein Families | Druggable Genome |
| MW | 42.7 kDa |
| Gene Summary | This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211524 | BRE (Myc-DDK-tagged)-Human brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 5 |
CN¥ 3,656.00 |
|
| RC211524L3 | Lenti ORF clone of Human brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 5, Myc-DDK-tagged |
CN¥ 5,890.00 |
|
| RC211524L4 | Lenti ORF clone of Human brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 5, mGFP tagged |
CN¥ 5,890.00 |
|
| RG211524 | BRE (tGFP-tagged) - Human brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), transcript variant 5 |
CN¥ 4,370.00 |
