BRCC45 (BRE) Rabbit Polyclonal Antibody

CAT#: TA349720

Rabbit Polyclonal Anti-BRE Antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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经常一起买 (2)
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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: A431 cells
IHC: 50-200
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein of human BRE
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 44 kDa
Gene Name brain and reproductive organ-expressed (TNFRSF1A modulator)
Background Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
Synonyms BRCC4; BRCC45
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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