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TAB3 (NM_152787) Human Untagged Clone
CAT＃: SC310156
TAB3 (untagged)-Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3)
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MAP3K7IP3; NAP1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC310156 representing NM_152787.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGCAAAGCAGCCCACAGCTTGATATTCAGGTTCTCCATGATCTTCGACAACGTTTCCCTGAAATT CCAGAGGGCGTGGTGTCTCAGTGCATGTTACAGAATAACAACAATCTTGAAGCCTGTTGCCGAGCCCTT TCCCAGGAGAGTAGCAAATACTTATATATGGAATACCATAGTCCAGATGACAATAGGATGAATAGAAAT CGCCTTTTACATATTAACCTGGGTATCCATTCTCCTAGTAGCTATCACCCAGGAGATGGAGCCCAACTT AATGGTGGTCGAACACTGGTACATAGCTCAAGTGATGGACATATTGATCCTCAGCATGCAGCAGGTAAA CAGCTGATATGTTTAGTTCAAGAACCACACTCAGCTCCAGCTGTTGTTGCTGCTACTCCCAACTACAAT CCATTTTTTATGAACGAACAGAACAGAAGTGCAGCTACTCCTCCTTCACAACCACCTCAACAGCCATCT TCCATGCAAACAGGAATGAATCCGTCTGCTATGCAAGGGCCTTCACCACCACCGCCACCTCCTTCATAC ATGCACATACCTCGGTATAGTACAAATCCAATTACTGTTACAGTATCCCAGAACCTCCCTTCTGGACAG ACTGTACCAAGAGCTTTACAAATTCTTCCACAAATTCCAAGCAATCTCTATGGGTCTCCTGGTTCTATT TATATTAGACAGACATCTCAGAGTTCATCAGGAAGACAAACTCCTCAGAGTACGCCGTGGCAGTCCTCA CCACAGGGCCCAGTGCCTCACTATAGCCAGCGTCCTTTACCTGTTTATCCACACCAACAGAACTATCAG CCTTCTCAGTATTCTCCCAAACAGCAGCAGATCCCTCAGTCTGCTTACCATTCACCACCTCCTTCTCAA TGTCCTTCACCCTTCAGCTCTCCACAGCATCAAGTGCAACCTTCCCAGTTGGGCCACATCTTTATGCCA CCTAGTCCTTCAACTACTCCACCCCATCCATATCAACAAGGACCTCCTAGCTATCAGAAACAGGGAAGC CATTCAGTAGCCTATCTTCCATACACAGCATCTAGTTTATCCAAAGGTTCCATGAAGAAGATAGAAATT ACAGTTGAACCTTCTCAAAGACCTGGGACAGCAATTAATAGGAGTCCTTCACCCATCAGTAATCAACCA TCTCCACGGAATCAACACTCACTGTACACAGCCACCACGCCACCTTCAAGTTCTCCTTCAAGAGGGATA TCTAGTCAACCAAAACCTCCATTTAGTGTTAATCCTGTGTATATTACATATACACAGCCAACTGGACCT TCTTGTACTCCATCACCATCTCCTCGAGTGATACCAAACCCAACTACAGTTTTTAAAATTACCGTAGGC CGAGCAACGACTGAAAATCTTTTAAATTTAGTGGACCAAGAAGAGCGCTCTGCAGCACCAGAACCTATT CAGCCCATTTCAGTGATACCAGGCTCTGGGGGAGAAAAGGGAAGCCATAAATATCAGAGAAGTTCTAGT TCTGGATCAGATGACTATGCCTACACACAAGCCTTGCTGTTACATCAACGAGCAAGGATGGAGAGGTTA GCAAAGCAACTGAAACTTGAGAAAGAGGAGCTAGAGCGGTTGAAGTCTGAAGTTAATGGTATGGAGCAT GACCTGATGCAGAGACGGCTCAGAAGAGTCAGCTGCACCACTGCGATCCCTACGCCTGAGGAAATGACA AGATTGAGAAGCATGAACAGACAACTCCAGATAAATGTTGACTGTACACTGAAAGAAGTTGACCTCCTT CAATCTAGAGGAAACTTTGATCCAAAAGCCATGAATAATTTTTATGACAACATAGAACCTGGCCCAGTT GTACCACCCAAGCCATCTAAAAAAGACTCCTCAGACCCCTGCACAATTGAGAGAAAAGCCCGAAGAATT AGCGTGACCTCCAAAGTACAGGCAGACATCCATGACACCCAGGCAGCAGCTGCAGATGAGCATCGAACT GGCTCCACACAAAGTCCTCGGACACAACCTCGAGATGAAGACTACGAAGGGGCTCCATGGAATTGTGAT AGCTGCACCTTTCTTAACCACCCAGCACTAAATCGCTGTGAGCAGTGCGAGATGCCACGGTACACCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_152787 |
| Insert Size | 2139 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_152787.4 |
| RefSeq Size | 6798 bp |
| RefSeq ORF | 2139 bp |
| Locus ID | 257397 |
| UniProt ID | Q8N5C8 |
| Domains | zf-RanBP, CUE |
| Protein Families | Druggable Genome |
| Protein Pathways | NOD-like receptor signaling pathway |
| MW | 78.7 kDa |
| Gene Summary | The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Identification of a distinct substrate binding domain in the bacterial cysteine methyltransferase effectors NleE and OspZ
,Zhang, Y;M Uumlhlen, S;Oates, CV;Pearson, JS;Hartland, EL;,
J. Biol. Chem.
,PubMed ID 27445336
[TAB3]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207646 | TAB3 (Myc-DDK-tagged)-Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3) |
CNY 5,216.00 |
|
| RC207646L1 | Lenti ORF clone of Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3), Myc-DDK-tagged |
CNY 7,616.00 |
|
| RC207646L2 | Lenti ORF clone of Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3), mGFP tagged |
CNY 5,890.00 |
|
| RC207646L3 | Lenti ORF clone of Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207646L4 | Lenti ORF clone of Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3), mGFP tagged |
CNY 5,890.00 |
|
| RG207646 | TAB3 (tGFP-tagged) - Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3) |
CNY 6,816.00 |
