TAB3 (NM_152787) Human Tagged ORF Clone
CAT#: RC207646
- TrueORF®
TAB3 (Myc-DDK-tagged)-Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3)
ORF Plasmid: tGFP
"NM_152787" in other vectors (6)
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CNY 5,216.00
Cited in 2 publications. |
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | MAP3K7IP3; NAP1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC207646 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGCAAAGCAGCCCACAGCTTGATATTCAGGTTCTCCATGATCTTCGACAACGTTTCCCTGAAATTC CAGAGGGCGTGGTGTCTCAGTGCATGTTACAGAATAACAACAATCTTGAAGCCTGTTGCCGAGCCCTTTC CCAGGAGAGTAGCAAATACTTATATATGGAATACCATAGTCCAGATGACAATAGGATGAATAGAAATCGC CTTTTACATATTAACCTGGGTATCCATTCTCCTAGTAGCTATCACCCAGGAGATGGAGCCCAACTTAATG GTGGTCGAACACTGGTACATAGCTCAAGTGATGGACATATTGATCCTCAGCATGCAGCAGGTAAACAGCT GATATGTTTAGTTCAAGAACCACACTCAGCTCCAGCTGTTGTTGCTGCTACTCCCAACTACAATCCATTT TTTATGAACGAACAGAACAGAAGTGCAGCTACTCCTCCTTCACAACCACCTCAACAGCCATCTTCCATGC AAACAGGAATGAATCCGTCTGCTATGCAAGGGCCTTCACCACCACCGCCACCTCCTTCATACATGCACAT ACCTCGGTATAGTACAAATCCAATTACTGTTACAGTATCCCAGAACCTCCCTTCTGGACAGACTGTACCA AGAGCTTTACAAATTCTTCCACAAATTCCAAGCAATCTCTATGGGTCTCCTGGTTCTATTTATATTAGAC AGACATCTCAGAGTTCATCAGGAAGACAAACTCCTCAGAGTACGCCGTGGCAGTCCTCACCACAGGGCCC AGTGCCTCACTATAGCCAGCGTCCTTTACCTGTTTATCCACACCAACAGAACTATCAGCCTTCTCAGTAT TCTCCCAAACAGCAGCAGATCCCTCAGTCTGCTTACCATTCACCACCTCCTTCTCAATGTCCTTCACCCT TCAGCTCTCCACAGCATCAAGTGCAACCTTCCCAGTTGGGCCACATCTTTATGCCACCTAGTCCTTCAAC TACTCCACCCCATCCATATCAACAAGGACCTCCTAGCTATCAGAAACAGGGAAGCCATTCAGTAGCCTAT CTTCCATACACAGCATCTAGTTTATCCAAAGGTTCCATGAAGAAGATAGAAATTACAGTTGAACCTTCTC AAAGACCTGGGACAGCAATTAATAGGAGTCCTTCACCCATCAGTAATCAACCATCTCCACGGAATCAACA CTCACTGTACACAGCCACCACGCCACCTTCAAGTTCTCCTTCAAGAGGGATATCTAGTCAACCAAAACCT CCATTTAGTGTTAATCCTGTGTATATTACATATACACAGCCAACTGGACCTTCTTGTACTCCATCACCAT CTCCTCGAGTGATACCAAACCCAACTACAGTTTTTAAAATTACCGTAGGCCGAGCAACGACTGAAAATCT TTTAAATTTAGTGGACCAAGAAGAGCGCTCTGCAGCACCAGAACCTATTCAGCCCATTTCAGTGATACCA GGCTCTGGGGGAGAAAAGGGAAGCCATAAATATCAGAGAAGTTCTAGTTCTGGATCAGATGACTATGCCT ACACACAAGCCTTGCTGTTACATCAACGAGCAAGGATGGAGAGGTTAGCAAAGCAACTGAAACTTGAGAA AGAGGAGCTAGAGCGGTTGAAGTCTGAAGTTAATGGTATGGAGCATGACCTGATGCAGAGACGGCTCAGA AGAGTCAGCTGCACCACTGCGATCCCTACGCCTGAGGAAATGACAAGATTGAGAAGCATGAACAGACAAC TCCAGATAAATGTTGACTGTACACTGAAAGAAGTTGACCTCCTTCAATCTAGAGGAAACTTTGATCCAAA AGCCATGAATAATTTTTATGACAACATAGAACCTGGCCCAGTTGTACCACCCAAGCCATCTAAAAAAGAC TCCTCAGACCCCTGCACAATTGAGAGAAAAGCCCGAAGAATTAGCGTGACCTCCAAAGTACAGGCAGACA TCCATGACACCCAGGCAGCAGCTGCAGATGAGCATCGAACTGGCTCCACACAAAGTCCTCGGACACAACC TCGAGATGAAGACTACGAAGGGGCTCCATGGAATTGTGATAGCTGCACCTTTCTTAACCACCCAGCACTA AATCGCTGTGAGCAGTGCGAGATGCCACGGTACACC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC207646 protein sequence
Red=Cloning site Green=Tags(s) MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQESSKYLYMEYHSPDDNRMNRNR LLHINLGIHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICLVQEPHSAPAVVAATPNYNPF FMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPPPPSYMHIPRYSTNPITVTVSQNLPSGQTVP RALQILPQIPSNLYGSPGSIYIRQTSQSSSGRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQY SPKQQQIPQSAYHSPPPSQCPSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAY LPYTASSLSKGSMKKIEITVEPSQRPGTAINRSPSPISNQPSPRNQHSLYTATTPPSSSPSRGISSQPKP PFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAPEPIQPISVIP GSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEELERLKSEVNGMEHDLMQRRLR RVSCTTAIPTPEEMTRLRSMNRQLQINVDCTLKEVDLLQSRGNFDPKAMNNFYDNIEPGPVVPPKPSKKD SSDPCTIERKARRISVTSKVQADIHDTQAAAADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPAL NRCEQCEMPRYT TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_152787 |
ORF Size | 2136 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_152787.5 |
RefSeq Size | 6798 bp |
RefSeq ORF | 2139 bp |
Locus ID | 257397 |
UniProt ID | Q8N5C8 |
Domains | zf-RanBP, CUE |
Protein Families | Druggable Genome |
Protein Pathways | NOD-like receptor signaling pathway |
MW | 78.7 kDa |
Gene Summary | The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Identification of a Distinct Substrate-binding Domain in the Bacterial Cysteine Methyltransferase Effectors NleE and OspZ
,null,
The Journal of Biological Chemistry
,PubMed ID 27445336
[TAB3]
|
Enterovirus 71 3C inhibits cytokine expression through cleavage of the TAK1/TAB1/TAB2/TAB3 complex
,Lei, X;Han, N;Xiao, X;Jin, Q;He, B;Wang, J;,
J. Virol.
,PubMed ID 24942571
[TAB3]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC207646L1 | Lenti ORF clone of Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3), Myc-DDK-tagged |
CNY 7,616.00 |
|
RC207646L2 | Lenti ORF clone of Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3), mGFP tagged |
CNY 5,890.00 |
|
RC207646L3 | Lenti ORF clone of Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC207646L4 | Lenti ORF clone of Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3), mGFP tagged |
CNY 5,890.00 |
|
RG207646 | TAB3 (tGFP-tagged) - Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3) |
CNY 6,816.00 |
|
SC310156 | TAB3 (untagged)-Human TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3) |
CNY 7,220.00 |