SIPA1L3 (NM_015073) Human Untagged Clone
CAT#: SC304219
SIPA1L3 (untagged)-Human signal-induced proliferation-associated 1 like 3 (SIPA1L3)
CNY 26,790.00
货期*
4周
规格
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CTRCT45; SPAL3; SPAR3 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC304219 representing NM_015073.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGACCACCTATCGGGCCATCCCCAGCGATGGTGTGGACCTGGCAGCCAGCTGTGGCGCCAGGGTGGGC GATGTCCTCCCTGGGCCACACACAGGGGACTACGCTCCCTTGGGATTCTGGGCCCAGAATGGCAGCATG TCCCAGCCTCTTGGCGAGAGCCCGGCCACCGCCACCGCCACCGCCACCGCCACCACCCGCCCCAGCCCC ACCACTCCCGCAATGCCCAAGATGGGCGTGCGCGCAAGGGTGGCCGACTGGCCGCCCAAGCGGGAGGCC CTGAGAGAGCACAGCAACCCAAGCCCCTCCCAGGACACAGATGGCACAAAGGCCACCAAGATGGCCCAT TCCATGAGGAGCATACAGAACGGACAGCCCCCCACCAGCACCCCGGCTTCCTCAGGGTCCAAAGCCTTC CACCGACTCTCCAGGAGAAGGTCCAAAGACGTGGAGTTCCAGGACGGGTGGCCCCGGTCCCCCGGCAGG GCCTTCCTCCCCCTTCGGCACCGCAGCAGCAGCGAGATCACCCTCAGCGAGTGTGACGCGGAGGACGCG GGGGAGCCGCGGGGGGCCCGGCACACGGGGGCGCTGCCCCTCTTCCGCGAGTACGGGAGCACCTCGTCC ATCGACGTGCAGGGCATGCCCGAGCAGAGCTTCTTCGACATCCTGAACGAGTTCCGCAGCGAGCAGCCC GACGCCCGAGGGTGCCAGGCCCTCACCGAGCTCCTCCGGGCAGATCCTGGCCCACACCTCATGGGGGGC GGCGGCGGAGCCAAGGGGGACTCCCACAACGGGCAGCCCGCCAAGGACAGCCTCCTGCCACTGCAGCCC ACGAAGGAGAAGGAGAAGGCCCGGAAGAAACCTGCGCGGGGCCTCGGCGGCGGGGACACGGTGGACTCG TCCATCTTTCGGAAGCTAAGGAGCAGCAAACCCGAGGGGGAGGCTGGGCGTTCCCCGGGGGAGGCCGAC GAGGGCCGGAGCCCCCCGGAAGCCAGCAGGCCGTGGGTGTGTCAGAAGAGCTTCGCCCACTTCGACGTG CAGAGCATGCTGTTCGACCTCAACGAGGCGGCCGCCAACAGGGTGTCGGTGTCGCAGCGGCGGAACACC ACCACGGGTGCTTCGGCCGCTTCCGCCGCCTCGGCCATGGCCTCCCTCACGGCCTCGCGGGCCCACAGC CTCGGAGGCCTGGACCCGGCCTTCACCAGCACAGAGGACCTAAACTGCAAGGAGAACTTGGAGCAGGAC CTCGGCGATGACAACAGCAACGACCTGCTGCTCAGCTGCCCGCACTTCCGCAATGAGATCGGGGGCGAG TGTGAGCGCAACGTGAGCTTCTCCCGGGCTTCCGTGGGCTCCCCGAGCAGCGGCGAGGGCCACCTGGCA GAGCCCGCCCTGAGCGCCTACCGCACCAACGCCAGCATCTCGGTGTTGGAAGTTCCCAAGGAGCAGCAG CGGACGCAGAGTCGGCCCCGGCAGTACAGCATCGAGCATGTGGACCTGGGCGCCCGCTACTACCAGGAT TACTTCGTGGGCAAAGAACATGCCAATTACTTCGGCGTGGATGAGAAGCTGGGGCCAGTGGCTGTGAGC ATTAAGCGGGAGAAGCTGGAAGACCACAAGGAGCACGGACCTCAGTACCAGTACAGGATCATCTTCCGG ACCCGCGAGCTCATCACCCTGCGGGGCTCCATCCTGGAAGATGCTACGCCCACAGCCACCAAGCATGGG ACCGGGCGGGGCCTGCCCTTGAAGGATGCCCTGGAGTATGTCATCCCCGAGCTCAACATCCACTGCCTG CGGCTGGCCCTCAACACCCCCAAGGTGACGGAGCAACTGCTGAAGCTCGATGAGCAAGGGCTCTGCCGG AAGCACAAGGTGGGCATCCTCTATTGCAAGGCCGGCCAGAGCTCCGAGGAGGAGATGTACAACAATGAG GAGGCCGGCCCCGCCTTTGAGGAGTTCCTCTCCCTCATCGGCGAGAAGGTCTGCCTGAAGGGCTTCACC AAGTACGCTGCCCAGCTGGACGTCAAGACCGACTCCACGGGAACCCACTCCCTCTACACGATGTACCAG GACTACGAGATCATGTTCCATGTCTCCACCCTGCTCCCTTACACCCCCAACAACAGGCAGCAGCTGCTA CGGAAGAGGCACATAGGAAATGACATCGTGACGATCATCTTCCAGGAGCCTGGCGCGCTACCGTTCACC CCCAAGAACATCCGCTCCCACTTCCAGCACGTCTTCATCATTGTCCGAGTCCACAACCCCTGCACTGAT AACGTCTGTTACAGTATGGCTGTGACCCGATCCAAAGACGCTCCTCCTTTCGGCCCCCCCATCCCCAGT GGAACCACATTCCGCAAATCCGACGTCTTCAGAGACTTCTTGCTGGCCAAGGTGATTAACGCTGAGAAC GCCGCGCACAAGTCCGACAAGTTCCACACCATGGCCACCAGGACCCGCCAGGAGTATCTCAAGGACCTG GCCGAAAACTGTGTCTCCAACACCCCCATCGACTCCACCGGCAAATTCAACCTCATCTCCCTGACCTCC AAGAAGAAGGAAAAGACAAAAGCACGGGCTGGCGCTGAGCAGCACAGTGCAGGGGCCATCGCCTGGAGG GTGGTGGCCCAGGACTACGCCCAGGGGGTGGAAATCGACTGCATTTTGGGAATTTCCAATGAGTTTGTG GTGCTCCTGGACTTACGCACCAAGGAGGTGGTGTTCAACTGCTACTGCGGGGATGTCATTGGCTGGACT CCAGACTCCTCCACACTCAAAATCTTCTATGGACGAGGAGACCACATCTTCCTACAGGCGACAGAGGGT TCTGTGGAGGACATAAGGGAGATAGTGCAGAGACTGAAGGTGATGACCAGTGGCTGGGAGACGGTGGAC ATGACGCTTCGGCGGAACGGGCTCGGGCAGCTGGGCTTCCACGTGAAGTACGACGGCACGGTGGCCGAG GTTGAGGACTATGGGTTCGCCTGGCAGGCCGGCCTCCGGCAGGGCAGCCGACTAGTGGAGATCTGCAAG GTGGCCGTGGTCACACTGACCCACGACCAGATGATCGACCTGCTGCGCACCTCTGTCACTGTGAAGGTG GTCATCATCCCGCCTTTTGAGGACGGCACTCCCCGGAGGGGTTGGCCGGAGACCTACGACATGAATACC TCGGAGCCCAAGACGGAGCAGGAAAGCATCACTCCTGGGGGCCGGCCCCCCTACCGCAGCAATGCTCCC TGGCAGTGGAGCGGGCCCGCATCCCATAACTCTCTACCAGCCTCCAAGTGGGCCACTCCAACCACTCCC GGCCATGCCCAGTCCCTGAGCCGGCCCCTGAAGCAGACCCCCATAGTCCCCTTCCGGGAGTCCCAGCCA CTGCACAGCAAGAGGCCTGTCAGCTTCCCAGAAACCCCTTACACAGTATCACCAGCAGGGGCCGACAGA GTCCCTCCCTACCGACAGCCTTCTGGGAGCTTCTCCACCCCCGGTTCGGCCACCTACGTGAGATACAAG CCATCCCCAGAAAGGTACACGGCTGCCCCACACCCCCTGCTATCTCTTGATCCCCACTTCAGCCACGAT GGGACGTCCAGCGGCGACTCCTCTTCCGGCGGCCTGACCAGCCAGGAGAGCACCATGGAACGCCAGAAG CCAGAGCCTTTGTGGCATGTGCCTGCCCAGGCCAGGCTCTCAGCCATAGCCGGAAGCAGCGGGAACAAG CACCCGTCCAGGCAGGATGCAGCAGGCAAAGATTCCCCCAACAGGCATTCCAAAGGAGAACCTCAATAC TCAAGTCATTCCAGCAGCAACACCCTCTCCAGCAACGCATCCAGCAGCCACAGCGACGACCGCTGGTTC GACCCCCTGGACCCCCTGGAGCCAGAGCAAGACCCCCTCTCCAAGGGTGGCTCTAGTGACAGCGGCATC GACACCACCCTCTACACCTCCAGCCCTAGCTGCATGTCCCTGGCCAAGGCTCCACGGCCCGCCAAGCCA CACAAGCCCCCTGGAAGTATGGGCCTTTGTGGCGGGGGTCGCGAGGCCGCTGGGAGGTCCCACCACGCA GACAGGCGGCGGGAGGTCTCCCCTGCCCCCGCAGTTGCCGGCCAAAGCAAGGGCTACCGACCGAAGCTG TACTCCTCCGGCTCCAGCACCCCCACGGGACTGGCGGGGGGCAGCCGAGACCCACCGAGGCAGCCCAGT GACATGGGCTCGAGGGTTGGCTACCCCGCTCAGGTTTACAAAACTGCCAGTGCAGAGACTCCTCGGCCC TCCCAGCTGGCCCAGCCCAGCCCCTTTCAGCTCTCCGCCTCCGTCCCCAAGTCCTTCTTCTCCAAGCAG CCTGTACGCAATAAGCACCCAACAGGGTGGAAGAGAACGGAGGAGCCCCCACCACGGCCACTCCCCTTC AGTGACCCAAAGAAGCAGGTGGACACGAACACCAAAAATGTCTTTGGGCAACCGAGGTTGAGGGCATCC CTCCGAGACCTCCGGTCACCACGGAAGAACTACAAATCCACCATCGAGGATGACCTGAAGAAACTCATC ATCATGGACAACCTGGGGCCAGAGCAGGAGAGAGACACGGGACAGTCACCGCAGAAGGGCCTGCAGCGG ACGCTGTCGGACGAGAGCCTGTGCAGCGGGCGCCGGGAGCCCAGCTTCGCCAGCCCCGCTGGCCTAGAG CCAGGGCTGCCCAGCGACGTGCTCTTCACCAGCACCTGCGCCTTCCCGTCCAGCACGCTGCCTGCACGC CGCCAGCACCAGCACCCCCACCCGCCCGTCGGCCCCGGTGCCACCCCTGCCGCCGGCAGCGGCTTTCCC GAGAAGAAATCCACCATCTCAGCCTCGGAGCTCTCGCTGGCTGATGGGCGGGACCGCCCCCTGCGGCGC CTGGACCCTGGGCTGATGCCCCTGCCTGACACAGCTGCTGGCCTCGAGTGGTCCAGCCTGGTGAACGCA GCCAAGGCATACGAAGTGCAAAGAGCCGTCTCACTCTTCTCTCTGAACGACCCGGCCCTGAGCCCGGAC ATCCCGCCTGCACACAGTCCTGTCCACAGCCACCTGAGCCTGGAGAGGGGACCCCCGACCCCCAGGACC ACCCCTACCATGAGCGAGGAGCCACCCCTGGATCTGACAGGCAAGGTGTACCAGCTGGAGGTGATGCTG AAACAGCTGCACACTGACCTGCAGAAGGAGAAGCAGGACAAGGTGGTGCTCCAGTCAGAGGTGGCCAGC CTGCGGCAGAACAACCAGCGGCTGCAGGAGGAGTCGCAGGCCGCCAGCGAGCAGCTGCGCAAGTTTGCG GAGATCTTCTGCAGGGAGAAGAAGGAGCTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_015073 |
Insert Size | 5346 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_015073.2 |
RefSeq Size | 8018 bp |
RefSeq ORF | 5346 bp |
Locus ID | 23094 |
UniProt ID | O60292 |
MW | 194.6 kDa |
Gene Summary | This gene belongs to the signal induced proliferation associated 1 family of genes, which encode GTPase-activating proteins specific for the GTP-binding protein Rap1. Rap1 has been implicated in regulation of cell adhesion, cell polarity, and organization of the cytoskeleton. Like other members of the family, the protein encoded by this gene contains RapGAP and PDZ domains. In addition, this protein contains a C-terminal leucine zipper domain. This gene is proposed to function in epithelial cell morphogenesis and establishment or maintenance of polarity. Consistently, expression of the protein in cell culture showed localization to cell-cell borders in apical regions, and downregulation of the gene in 3D Caco2 cell culture resulted in abnormal cell polarity and morphogenesis. Allelic variants of this gene have been associated with congenital cataracts in humans. [provided by RefSeq, Feb 2016] |
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