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TRPM2 (NM_003307) Human Untagged Clone
CAT＃: SC303292
TRPM2 (untagged)-Human transient receptor potential cation channel, subfamily M, member 2 (TRPM2), transcript variant 1
CNY 10,288.00
货期*
现货
规格
| Cited in 1 publication. |
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EREG1; KNP3; LTrpC-2; LTRPC2; NUDT9H; NUDT9L1; TRPC7 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>SC303292 representing NM_003307.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GAATTCGCCCTTGTAGCGAGCTGGAGAGAGGACTGTCCTGAGGGCAGCAGGCCTGGTTGCAGCTGGCGT GGGGGTCTCAGAATGGAGCCCTCAGCCCTGAGGAAAGCTGGCTCGGAGCAGGAGGAGGGCTTTGAGGGA CTGCCCAGAAGGGTCACTGACCTGGGGATGGTCTCCAATCTCCGGCGCAGCAACAGCAGCCTCTTCAAG AGCTGGAGGCTACAGTGCCCCTTCGGCAACAATGACAAGCAAGAAAGCCTCAGTTCGTGGATTCCTGAA AACATCAAGAAGAAAGAATGCGTGTATTTTGTGGAAAGTTCCAAACTGTCTGATGCTGGGAAGGTGGTG TGTCAGTGTGGCTACACGCATGAGCAGCACTTGGAGGAGGCTACCAAGCCCCACACCTTCCAGGGCACA CAGTGGGACCCAAAGAAACATGTCCAGGAGATGCCAACCGATGCCTTTGGCGACATCGTCTTCACGGGC CTGAGCCAGAAGGTGAAAAAGTACGTCCGAGTCTCCCAGGACACGCCCTCCAGCGTGATCTACCACCTC ATGACCCAGCACTGGGGGCTGGACGTCCCCAATCTCTTGATCTCGGTGACCGGGGGGGCCAAGAACTTC AACATGAAGCCGCGGCTGAAGAGCATTTTCCGCAGAGGCCTGGTCAAGGTGGCTCAGACCACAGGGGCC TGGATCATCACAGGGGGGTCCCACACCGGCGTCATGAAGCAGGTAGGCGAGGCGGTGCGGGACTTCAGC CTGAGCAGCAGCTACAAGGAAGGCGAGCTCATCACCATCGGAGTCGCCACCTGGGGCACTGTCCACCGC CGCGAGGGCCTGATCCATCCCACGGGCAGCTTCCCCGCCGAGTACATACTGGATGAGGATGGCCAAGGG AACCTGACCTGCCTAGACAGCAACCACTCTCACTTCATCCTCGTGGACGACGGGACCCACGGCCAGTAC GGGGTGGAGATTCCTCTGAGGACCAGGCTGGAGAAGTTCATATCGGAGCAGACCAAGGAAAGAGGAGGT GTGGCCATCAAGATCCCCATCGTGTGCGTGGTGCTGGAGGGCGGCCCGGGCACGTTGTACACCATCGAC AACGCCACCACCAACGGCACCCCCTGTGTGGTTGTGGAGGGCTCGGGCCGCGTGGCCGACGTCATTGCC CAGGTGGCCAACCTGCCTGTCTCGGACATCACTATCTCCCTGATCCAGCAGAAACTGAGCGTGTTCTTC CAGGAGATGTTTGAGACCTTCACGGAAAGCAGGATTGTCGAGTGGACCAAAAAGATCCAAGATATCGTC CGGAGGCGGCAGCTGCTGACTGTCTTCCGGGAAGGCAAGGATGGTCAGCAGGACGTGGATGTGGCCATC TTGCAGGCCTTGCTGAAAGCCTCACGGAGCCAAGACCACTTTGGCCACGAGAACTGGGACCACCAGCTG AAACTGGCAGTGGCATGGAATCGCGTGGACATTGCCCGCAGTGAGATCTTCATGGATGAGTGGCAGTGG AAGCCTTCAGATCTGCACCCCACGATGACAGCTGCACTCATCTCCAACAAGCCTGAGTTTGTGAAGCTC TTCCTGGAGAACGGGGTGCAGCTGAAGGAGTTTGTCACCTGGGACACCTTGCTCTACCTGTACGAGAAC CTGGACCCCTCCTGCCTGTTCCACAGCAAGCTGCAGAAGGTGCTGGTGGAGGATCCCGAGCGCCCGGCT TGCGCGCCCGCGGCGCCCCGCCTGCAGATGCACCACGTGGCCCAGGTGCTGCGGGAGCTGCTGGGGGAC TTCACGCAGCCGCTTTATCCCCGGCCCCGGCACAACGACCGGCTGCGGCTCCTGCTGCCCGTTCCCCAC GTCAAGCTCAACGTGCAGGGAGTGAGCCTCCGGTCCCTCTACAAGCGTTCCTCAGGCCATGTGACCTTC ACCATGGACCCCATCCGTGACCTTCTCATTTGGGCCATTGTCCAGAACCGTCGGGAGCTGGCAGGAATC ATCTGGGCTCAGAGCCAGGACTGCATCGCAGCGGCCTTGGCCTGCAGCAAGATCCTGAAGGAACTGTCC AAGGAGGAGGAGGACACGGACAGCTCGGAGGAGATGCTGGCGCTGGCGGAGGAGTATGAGCACAGAGCC ATCGGGGTCTTCACCGAGTGCTACCGGAAGGACGAAGAGAGAGCCCAGAAACTGCTCACCCGCGTGTCC GAGGCCTGGGGGAAGACCACCTGCCTGCAGCTCGCCCTGGAGGCCAAGGACATGAAGTTTGTGTCTCAC GGGGGCATCCAGGCCTTCCTGACCAAGGTGTGGTGGGGCCAGCTCTCCGTGGACAATGGGCTGTGGCGT GTGACCCTGTGCATGCTGGCCTTCCCGCTGCTCCTCACCGGCCTCATCTCCTTCAGGGAGAAGAGGCTG CAGGATGTGGGCACCCCCGCGGCCCGCGCCCGTGCCTTCTTCACCGCACCCGTGGTGGTCTTCCACCTG AACATCCTCTCCTACTTCGCCTTCCTCTGCCTGTTCGCCTACGTGCTCATGGTGGACTTCCAGCCTGTG CCCTCCTGGTGCGAGTGTGCCATCTACCTCTGGCTCTTCTCCTTGGTGTGCGAGGAGATGCGGCAGCTC TTCTATGACCCTGACGAGTGCGGGCTGATGAAGAAGGCAGCCTTGTACTTCAGTGACTTCTGGAATAAG CTGGACGTCGGCGCAATCTTGCTCTTCGTGGCAGGGCTGACCTGCAGGCTCATCCCGGCGACGCTGTAC CCCGGGCGCGTCATCCTCTCTCTGGACTTCATCCTGTTCTGCCTCCGGCTCATGCACATTTTTACCATC AGTAAGACGCTGGGGCCCAAGATCATCATTGTGAAGCGGATGATGAAGGACGTCTTCTTCTTCCTCTTC CTGCTGGCTGTGTGGGTGGTGTCCTTCGGGGTGGCCAAGCAGGCCATCCTCATCCACAACGAGCGCCGG GTGGACTGGCTGTTCCGAGGGGCCGTCTACCACTCCTACCTCACCATCTTCGGGCAGATCCCGGGCTAC ATCGACGGTGTGAACTTCAACCCGGAGCACTGCAGCCCCAATGGCACCGACCCCTACAAGCCTAAGTGC CCCGAGAGCGACGCGACGCAGCAGAGGCCGGCCTTCCCTGAGTGGCTGACGGTCCTCCTACTCTGCCTC TACCTGCTCTTCACCAACATCCTGCTGCTCAACCTCCTCATCGCCATGTTCAACTACACCTTCCAGCAG GTGCAGGAGCACACGGACCAGATTTGGAAGTTCCAGCGCCATGACCTGATCGAGGAGTACCACGGCCGC CCCGCCGCGCCGCCCCCCTTCATCCTCCTCAGCCACCTGCAGCTCTTCATCAAGAGGGTGGTCCTGAAG ACTCCGGCCAAGAGGCACAAGCAGCTCAAGAACAAGCTGGAGAAGAACGAGGAGGCGGCCCTGCTATCC TGGGAGATCTACCTGAAGGAGAACTACCTCCAGAACCGACAGTTCCAGCAAAAGCAGCGGCCCGAGCAG AAGATCGAGGACATCAGCAATAAGGTTGACGCCATGGTGGACCTGCTGGACCTGGACCCACTGAAGAGG TCGGGCTCCATGGAGCAGAGGTTGGCCTCCCTGGAGGAGCAGGTGGCCCAGACAGCCCGAGCCCTGCAC TGGATCGTGAGGACGCTGCGGGCCAGCGGCTTCAGCTCGGAGGCGGACGTCCCCACTCTGGCCTCCCAG AAGGCCGCGGAGGAGCCGGATGCTGAGCCGGGAGGCAGGAAGAAGACGGAGGAGCCGGGCGACAGCTAC CACGTGAATGCCCGGCACCTCCTCTACCCCAACTGCCCTGTCACGCGCTTCCCCGTGCCCAACGAGAAG GTGCCCTGGGAGACGGAGTTCCTGATCTATGACCCACCCTTTTACACGGCAGAGAGGAAGGACGCGGCC GCCATGGACCCCATGGGAGACACCCTGGAGCCACTGTCCACGATCCAGTACAACGTGGTGGATGGCCTG AGGGACCGCCGGAGCTTCCACGGGCCGTACACAGTGCAGGCCGGGTTGCCCCTGAACCCCATGGGCCGC ACAGGACTGCGTGGGCGCGGGAGCCTCAGCTGCTTCGGACCCAACCACACGCTGTACCCCATGGTCACG CGGTGGAGGCGGAACGAGGATGGAGCCATCTGCAGGAAGAGCATAAAGAAGATGCTGGAAGTGCTGGTG GTGAAGCTCCCTCTCTCCGAGCACTGGGCCCTGCCTGGGGGCTCCCGGGAGCCAGGGGAGATGCTACCT CGGAAGCTGAAGCGGATCCTCCGGCAGGAGCACTGGCCGTCTTTTGAAAACTTGCTGAAGTGCGGCATG GAGGTGTACAAAGGCTACATGGATGACCCGAGGAACACGGACAATGCCTGGATCGAGACGGTGGCCGTC AGCGTCCACTTCCAGGACCAGAATGACGTGGAGCTGAACAGGCTGAACTCTAACCTGCACGCCTGCGAC TCGGGGGCCTCCATCCGATGGCAGGTGGTGGACAGGCGCATCCCACTCTATGCGAACCACAAGACCCTC CTCCAGAAGGCAGCCGCTGAGTTCGGGGCTCACTACTGACTGTGCCCTCAGGCTGGGCGGCTCCAGTCC ATAGACGTTCCCCCCAGAAACCAGGGCTTCTCTCTCCTGAGCCTGGCCAGGACTCAGGCTGTTCCTGGG CCCTGCACATGATGGGGTTTGGTGGACCCAGTGCCCCTCACGGCTGCCGCAAGTCTGCTGCAGATGACC TCATGAACTGGAAGGGGTCAAGGTGACCCGGGAGGAGAGCTCAAGACAGGGCACAGGCTACTCAGAGCT GAGGGGCCCCTGGGACCCTTGGCCATCAGGCGAGGGGCTGGGCCTGTGCAGCTGGGCCCTTGGCCAGAG TCCACTCCCTTCCTGGCTGTGTCACCCCGAGCAGCTCATCCACCATGGAGGTCATCGGCCTGAGGCAAG TTCCCCGGAGAGTCGGGGTCCCCTGTGGCCCCCTCAGGCCTATGTCTGTGAGGAAGGGGCCCTGCCACT CTCCCCAAGAGGGCCTCCATGTTTCGAGGTGCCTCAACATGGAGCCTTGCCTGGCCTGGGCTAGGGGCA CTGTCTGAACTCCTGACTGTCAGGATAAACTCCGTGGGGGTACAGGAGCCCAGACAAAGCCCAGGCCTG TCAAGAGACGCAGAGGGCCCCTGCCAGGGTTGGCCCCAGGGACCCTGGGACGAGGCTGCAGAAGCTCTC CCTCCCTACTCCCTGGGAGCCACGTGCTGGCCATGTGGCCAGGGACGGCATGAGCAGGAGGCGGGGACG TGGGGGCCTTCTGGTTTGGTGTCAACAGCTCACAGGAGCGTGAACCATGAGGGCCCTCAGGAGGGGAAC GTGGTAAAACCCAAGACATTAAATCTGCCATCTCAGGCCTGGCTGGCTCTTCTGTGCTTTCCACAAATA AAGTTCCTGACACGTCCAGGGCCAGGGGCTGTGTGACGGCTGCCTGAAGTTCTCCTCAATCCCCCGGTG AGCTTCCTGCAGCCTGTGGATGTCCTGCAGCCCCTCAGCCCTACCCCCAAGTTTCTCCTCTGAAAAAAA AAAAAAAAAAAAAAAAAAAAAAACTCGACTCTAGA >Reverse primer walk for NM_003307 unedited
NGGGGCGATCGCCTTNCTTGTGACTGCTGCTCAGNCTGNAGATCCCGCACCGCCTCGCCT ACCTGCTTCATGACGCCGGTGTGGGACCCCCCTGTGATGATCCAGGCCCCTGTGGTCTGA GCCACCTTGACCAGGCCTCTGCGGAAAATGCTCTTCAGCCGCGGCTTCATGTTGAAGTTC TTGGCCCCCCCGGTCACCGAGATCAAGAGATTGGGGACGTCCAGCCCCCAGTGCTGGGTC ATGAGGTGGTAGATCACGCTGGAGGGCGTGTCCTGGGAGACTCGGACGTACTTTTTCACC TTCTGGCTCAGGCCCGTGAAGACGATGTCGCCAAAGGCATCGGTTGGCATCTCCTGGACA TGTTTCTTTGGGTCCCACTGTGTGCCCTGGAAGGTGTGGGGCTTGGTAGCCTCCTCCAAG TGCTGCTCATGCGTGTAGCCACACTGACACACCACCTTCCCAGCATCAGACAGTTTGGAA CTTTCCACAAAATACACGCATTCTTTCTTCTTGATGTTTTCAGGAATCCACGAACTGAGG CTTTCTTGCTTGTCATTGTTGNCCGAAGGGCACTGTAGCCTCCAGCTCTTGAAGAGGCTG CTGTTGCTGCGCCGGAGATTGGAGACCATCCCCAGGTCAGTGACCCTTCTGGGCAGTCCC TCAAAGCCCTCCTCCTGCTCCGAGCCAGCTTTTCCTCAGGCTGANGGCTCCATTCTGAGA CCCCCACGCCAGCTGCAACCAGGCCTGCTGCCCCTCAGACAGTCCTCTCTCCAGCTCGCT ACAAGGGCGAATTCGCGGCCGCTGCANAAGAAACAGTAGCTTGTATTCTATAGTGTCACC CTAATGAGCTCTGCTTATATAGACCTNCCACCGTAACACGCCTACCGGCCATTTNGCGTC ACGG >OriGene 3' genomic read for NM_003307 unedited
AGNAAAGCACTGGGGNAGGGTCACAGGGATGCCACCCGGGCTCTGTTCAGGAAACAGCTA TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTC AAAGGAAAAACTTGGGGGTAGGGCTGAGGGGCTGCAGGACATCCACAGGCTGCAGGAAGC TCACCGGGGGATCGAGGAGAACTTCAGGCAGCCGTCACACAGCCCCTGGCCCTGGACGTG TCAGGAACTTTATTTGTGGAAAGCACAGAAGAGCCAGCCAGGCCTGAGATGGCAGATTTA ATGTCTTGGGTTTTACCACGTTCCCCTCCTGAGGGCCCTCATGGTTCACGCTCCTGTGAG CTGTTGACACCAAACCAGAAGGCCCCCACGTCCCCGCCTCCTGCTCATGCCGTCCCTGGC CACATGGCCAGCACGTGGCTCCCAAGGAGTAGGGAGGGAGAGCTTCTTGCACCTCGTTCC CAGGTCCCTGGGGCCCACCCTTGCAGGGGCCCCTCTGCGTCTCNTGACAGGGCCTGGCTT TTTGTCTGGGCTCTGGTCCCCCACGGAGTTTATTCCTGAACGTCAAGAATTCAAAACGTG CCCCTTGCCCCAGCCAAGCAAGGCTTCATGTTGAGGCACCTTCAAACATTGGAGCCCTCC TGGGGAAAGTGGCAGGCCCCCTCCCTACAGACTAAGCCTGTAAGGGGCCACAGGGGACCC CGACTTTTCGGGGAACTTGCCTTAGCCGATTACCTTCATGGGTGGATGAACTGGTCTGGG TTGCCCCACCCCGAAGGGGATGGACTCTTGGCCAAGGGCCCAACTTGCCAGG |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_003307 |
| Insert Size | 5624 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There is 1 nucleotide difference between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substituion of 1 aa. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003307.3 |
| RefSeq Size | 5876 bp |
| RefSeq ORF | 5624 bp |
| Locus ID | 7226 |
| UniProt ID | O94759 |
| Protein Families | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane |
| MW | 210.7 kDa |
| Gene Summary | The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2016] Transcript Variant: This variant (1) encodes isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Four Ca2+ Ions Activate TRPM2 Channels by Binding in Deep Crevices near the Pore but Intracellularly of the Gate
,László Csanády and Beáta Törocsik,
J. Gen. Physiol., Feb 2009; 133: 189 - 203.
[TRPM2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216220 | TRPM2 (Myc-DDK-tagged)-Human transient receptor potential cation channel, subfamily M, member 2 (TRPM2), transcript variant 1 |
CNY 10,288.00 |
|
| RC216220L3 | Lenti-ORF clone of TRPM2 (Myc-DDK-tagged)-Human transient receptor potential cation channel, subfamily M, member 2 (TRPM2), transcript variant 1 |
CNY 16,910.00 |
|
| RC216220L4 | Lenti-ORF clone of TRPM2 (mGFP-tagged)-Human transient receptor potential cation channel, subfamily M, member 2 (TRPM2), transcript variant 1 |
CNY 12,688.00 |
|
| RG216220 | TRPM2 (tGFP-tagged) - Human transient receptor potential cation channel, subfamily M, member 2 (TRPM2), transcript variant 1 |
CNY 11,888.00 |
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