United States
Germany
Japan
United Kingdom
China
SOD2 (NM_000636) Human Untagged Clone
CAT＃: SC127816
SOD2 (untagged)-Human superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 3,600.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GClnc1; IPO-B; IPOB; Mn-SOD; MNSOD; MVCD6 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127816 sequence for NM_000636 edited (data generated by NextGen Sequencing)
ATGTTGAGCCGGGCAGTGTGCGGCACCAGCAGGCAGCTGGCTCCGGTTTTGGGGTATCTG GGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTACGACTACGGCGCCCTGGAACCT CACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAGCACCACGCGGCCTACGTGAAC AACCTGAACGTCACCGAGGAGAAGTACCAGGAGGCGTTGGCCAAGGGAGATGTTACAGCC CAGATAGCTCTTCAGCCTGCACTGAAGTTCAATGGTGGTGGTCATATCAATCATAGCATT TTCTGGACAAACCTCAGCCCTAACGGTGGTGGAGAACCCAAAGGGGAGTTGCTGGAAGCC ATCAAACGTGACTTTGGTTCCTTTGACAAGTTTAAGGAGAAGCTGACGGCTGCATCTGTT GGTGTCCAAGGCTCAGGTTGGGGTTGGCTTGGTTTCAATAAGGAACGGGGACACTTACAA ATTGCTGCTTGTCCAAATCAGGATCCACTGCAAGGAACAACAGGCCTTATTCCACTGCTG GGGATTGATGTGTGGGAGCACGCTTACTACCTTCAGTATAAAAATGTCAGGCCTGATTAT CTAAAAGCTATTTGGAATGTAATCAACTGGGAGAATGTAACTGAAAGATACATGGCTTGC AAAAAGTAA Clone variation with respect to NM_000636.2 >OriGene 5' read for NM_000636 unedited
GCGGCCGCGAATTCGGCACCAGTGCTCCCCGCGCTTTCTTAAGGCCCGCGGGCGGCGCAG GAGCGGCACTCGTGGCTGTGGTGGCTTCGGCAGCGGCTTCAGCAGATCGGCGGCATCAGC GGTAGCACCAGCACTAGCAGCATGTTGAGCCGGGCAGTGTGCGGCACCAGCAGGCAGCTG GCTCCGGTTTTGGGGTATCTGGGCTCCAGGCAGAAGCACAGCCTCCCCGACCTGCCCTAC GACTACGGCGCCCTGGAACCTCACATCAACGCGCAGATCATGCAGCTGCACCACAGCAAG CACCACGCGGCCTACGTGAACAACCTGAACGTCACCGAGGAGAAGTACCAGGAGGCGTTG GCCAAGGGAGATGTTACAGCCCAGATAGCTCTTCAGCCTGCACTGAAGTTCAATGGTGGT GGTCATATCAATCATAGCATTTTCTGGACAAACCTCAGCCCTAACGGTGGTGGAGAACCC AAAGGGGAGTTGCTGGAAGCCATCAAACGTGACTTTGGTTCCTTTGACAAGTTTAAGGAG AAGCTGACGGCTGCATCTGTTGGTGTCCAGGCTCAGGTTGGGGTTGGCTTGGTTTCATAA GGAACGGNGACACTTACAAATTGCTGCTTGTCCAATCAGGATCCACTGCAGGGAACACAG GCCTTATTCCACTGCTGGGGATTNGATGTGTGGGAGCACGCTTACTACCTTTCAGTATAA ATGTCAGGCCTGA >OriGene 3' read for NM_000636 unedited
CCCCATTCGTTTGGACCGTCGGCCGCAATCTACGATCGAGTTTTTTTTTTTTTTTTTTGA TGGTTGACAGATTCTTTTATTAACAGTCAAAAACTTCACACAGATTGGAAAATAAATGTT TTCTTCAATGAATAATCAAACAAAAATTATCCAGGACCTTATAGGGTTTTCAGTATGTAC CAGGCTTGATGCACATCTTAGAAGACAGGACATTATCTTGCTGGGATCATTAGGGTATGA CTGAAAGTGAGAAACAGTAATTTGTAAAACATTTACCTAATAATAGCTTTCCCAAACAGT ACTTCCCCTGGAATTAAAACAGGAAATACAATTTATGTTTATACGTGGTTTTAGATATGA CTCAATATACATAGATTTTAACTTTATGGTTTGGTATTACTTTTTTAAAGGCGCTCAATA GAAATTCAAATCTCACTTTAAGACCATGAATTTCAAGTTGCAATGAAGTGTACAATAAAG TTGTGATTTCTCAACATCAAAGTTTAATTATTACAAAATAGTTCAAGCAACAGATAGAAT TTCAAAAACAGTATTTGCTTTGCTTCCTTGTTTTGCTCCAACACTAATCATGCTGAGGTT TTTGAAGCACAGCTATGACTAGGGCAGGCACTGCTGATTCAGTCACAAAAACCCTTCTTG GATGAACAATACTTGGTCTTTTCAGAAGAAAAGCCATTTTACCTTTTCTATTTCTATTAT GAAAAACAGAGCTAAACAATTTTTGTATTTTTGTTGAAGAACCGGGGTTTTACCCCGTTT GGCCACCGCTGGTCCCGAACATCCTTAAGGGGTTTTGCCTGCCCTTGGCTTCCCAAGGGT TTGGATCACAAAGGCGAGTTACCCCGCCCAGCCCTTAACAATTTTAAAGGTCTCTTTTTC CCCACAAGCATTAAACTCTTAGTTGGCAAACCCCTTAACCCTA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000636 |
| Insert Size | 4300 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000636.2, NP_000627.2 |
| RefSeq Size | 1593 bp |
| RefSeq ORF | 669 bp |
| Locus ID | 6648 |
| UniProt ID | P04179 |
| Domains | sodfe |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Huntington's disease |
| Gene Summary | This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (A). Both variants 1 and 2 encode the same isoform (A). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
NADPH Oxidase Activation Is Required in Reactive Oxygen Species Generation and Cell Transformation Induced by Hexavalent Chromium
,Xin Wang, Young-Ok Son, Qingshan Chang, Lijuan Sun, J.Andrew Hitron, Amit Budhraja, Zhuo Zhang, Zunji Ke, Fei Chen, Jia Luo, and Xianglin Shi,
Toxicol. Sci., Oct 2011; 123: 399 - 410.
[SOD2]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202330 | SOD2 (Myc-DDK-tagged)-Human superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 3,600.00 |
|
| RC202330L1 | Lenti ORF clone of Human superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC202330L2 | Lenti ORF clone of Human superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC202330L3 | Lenti ORF clone of Human superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC202330L4 | Lenti ORF clone of Human superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 6,000.00 |
|
| RG202330 | SOD2 (tGFP-tagged) - Human superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 5,200.00 |
|
| SC323760 | SOD2 (untagged)-Human superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 3,600.00 |
