SOD2 Rabbit Monoclonal Antibody [Clone ID: OTIR4G8]

Specifications

Product Data
Clone Name	OTIR4G8
Applications	SISCAPA
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SOD2 (NP_000627). The exact sequence is proprietary.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	Lot dependent; please refer to CoA along with shipment
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	24.8 kDa
Gene Name	superoxide dismutase 2
Database Link	NP_000627 Entrez Gene 20656 MouseEntrez Gene 24787 RatEntrez Gene 6648 Human UniProt ID P04179
Background	This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]
Synonyms	GClnc1; IPO-B; IPOB; Mn-SOD; MNSOD; MVCD6
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Huntington's disease

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