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Metabotropic Glutamate Receptor 3 (GRM3) (NM_000840) Human Untagged Clone
CAT＃: SC125500
GRM3 (untagged)-Human glutamate receptor, metabotropic 3 (GRM3)
CNY 6,448.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GLUR3; GPRC1C; mGlu3; MGLUR3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000840 edited
GGCGGCCGCGAATTCGGCACGAGGCTTTTGTGTCGGATGAGGAGGACCAACCATGAGCCA GAGCCCGGGTGCAGGCTCACCGCCGCCGCTGCCACCGCGGTCAGCTCCAGTTCCTGCCAG GAGTTGTCGGTGCGAGGAATTTTGTGACAGGCTCTGTTAGTCTGTTCCTCCCTTATTTGA AGGACAGGCCAAAGATCCAGTTTGGAAATGAGAGAGGACTAGCATGACACATTGGCTCCA CCATTGATATCTCCCAGAGGTACAGAAACAGGATTCATGAAGATGTTGACAAGACTGCAA GTTCTTACCTTAGCTTTGTTTTCAAAGGGATTTTTACTCTCTTTAGGGGACCATAACTTT CTAAGGAGAGAGATTAAAATAGAAGGTGACCTTGTTTTAGGGGGCCTGTTTCCTATTAAC GAAAAAGGCACTGGAACTGAAGAATGTGGGCGAATCAATGAAGACCGAGGGATTCAACGC CTGGAAGCCATGTTGTTTGCTATTGATGAAATCAACAAAGATGATTACTTGCTACCAGGA GTGAAGTTGGGTGTTCACATTTTGGATACATGTTCAAGGGATACCTATGCATTGGAGCAA TCACTGGAGTTTGTCAGGGCATCTTTGACAAAAGTGGATGAAGCTGAGTATATGTGTCCT GATGGATCCTATGCCATTCAAGAAAACATCCCACTTCTCATTGCAGGGGTCATTGGTGGC TCTTATAGCAGTGTTTCCATACAGGTGGCAAACCTGCTGCGGCTCTTCCAGATCCCTCAG ATCAGCTACGCATCCACCAGCGCCAAACTCAGTGATAAGTCGCGCTATGATTACTTTGCC AGGACCGTGCCCCCCGACTTCTACCAGGCCAAAGCCATGGCTGAGATCTTGCGCTTCTTC AACTGGACCTACGTGTCCACAGTAGCCTCCGAGGGTGATTACGGGGAGACAGGGATCGAG GCCTTCGAGCAGGAAGCCCGCCTGCGCAACATCTGCATCGCTACGGCGGAGAAGGTGGGC CGCTCCAACATCCGCAAGTCCTACGACAGCGTGATCCGAGAACTGTTGCAGAAGCCCAAC GCGCGCGTCGTGGTCCTCTTCATGCGCAGCGACGACTCGCGGGAGCTCATTGCAGCCGCC AGCCGCGCCAATGCCTCCTTCACCTGGGTGGCCAGCGACGGCTGGGGCGCGCAGGAGAGC ATCATCAAGGGCAGCGAGCATGTGGCCTACGGCGCCATCACCCTGGAGCTGGCCTCCCAG CCTGTCCGCCAGTTCGACCGCTACTTCCAGAGCCTCAACCCCTACAACAACCACCGCAAC CCCTGGTTCCGGGACTTCTGGGAGCAAAAGTTTCAGTGCAGCCTCCAGAACAAACGCAAC CACAGGCGCGTCTGCGACAAGCACCTGGCCATCGACAGCAGCAACTACGAGCAAGAGTCC AAGATCATGTTTGTGGTGAACGCGGTGTATGCCATGGCCCACGCTTTGCACAAAATGCAG CGCACCCTCTGTCCCAACACTACCAAGCTTTGTGATGCTATGAAGATCCTGGATGGGAAG AAGTTGTACAAGGATTACTTGCTGAAAATCAACTTCACGGCTCCATTCAACCCAAATAAA GATGCAGATAGCATAGTCAAGTTTGACACTTTTGGAGATGGAATGGGGCGATACAACGTG TTCAATTTCCAAAATGTAGGTGGAAAGTATTCCTACTTGAAAGTTGGTCACTGGGCAGAA ACCTTATCGCTAGATGTCAACTCTATCCACTGGTCCCGGAACTCAGTCCCCACTTCCCAG TGCAGCGACCCCTGTGCCCCCAATGAAATGAAGAATATGCAACCAGGGGATGTCTGCTGC TGGATTTGCATCCCCTGTGAACCCTACGAATACCTGGCTGATGAGTTTACCTGTATGGAT TGTGGGTCTGGACAGTGGCCCACTGCAGACCTAACTGGATGCTATGACCTTCCTGAGGAC TACATCAGGTGGGAAGACGCCTGGGCCATTGGCCCAGTCACCATTGCCTGTCTGGGTTTT ATGTGTACATGCATGGTTGTAACTGTTTTTATCAAGCACAACAACACACCCTTGGTCAAA GCATCGGGCCGAGAACTCTGCTACATCTTATTGTTTGGGGTTGGCCTGTCATACTGCATG ACATTCTTCTTCATTGCCAAGCCATCACCAGTCATTTGTGCATTGCGCCGACTCGGGCTG GGGAGTTCCTTCGCTATCTGTTACTCAGCCCTGCTGACCAAGACAAACTGCATTGCCCGC ATCTTCGATGGGGTCAAGAATGGCGCTCAGAGGCCAAAATTCATCAGCCCCAGTTCTCAG GTTTTCATCTGCCTGGGTCTGATCCTGGTGCAAATTGTGATGGTGTCTGTGTGGCTCATC CTGGAGGCCCCAGGCACCAGGAGGTATACCCTTGCAGAGAAGCGGGAAACAGTCATCCTA AAATGCAATGTCAAAGATTCCAGCATGTTGATCTCTCTTACCTACGATGTGATCCTGGTG ATCTTATGCACTGTGTACGCCTTCAAAACGCGGAAGTGCCCAGAAAATTTCAACGAAGCT AAGTTCATAGGTTTTACCATGTACACCACGTGCATCATCTGGTTGGCCTTCCTCCCTATA TTTTATGTGACATCAAGTGACTACAGAGTGCAGACGACAACCATGTGCATCTCTGTCAGC CTGAGTGGCTTTGTGGTCTTGGGCTGTTTGTTTGCACCCAAGGTTCACATCATCCTGTTT CAACCCCAGAAGAATGTTGTCACACACAGACTGCACCTCAACAGGTTCAGTGTCAGTGGA ACTGGGACCACATACTCTCAGTCCTCTGCAAGCACGTATGTGCCAACGGTGTGCAATGGG CGGGAAGTCCTCGACTCCACCACCTCATCTCTGTGATTGTGAATTGCAGTTCAGTTCTTG TGTTTTTAGACTGTTAGACAAAAGTGCTCACGTGCAGCTCCAGAATATGGAAACAGAGCA AAAGAACAACCCTAGTACCTTTTTTTAGAAACAGTACGATAAATTATTTTTGAGGACTGT ATATAGTGATGTGCTAGAACTTTCTAGGCTGAGTCTAGTGCCCCTATTATTAACAATTCC CCCAGAACATGGAAATAACCATTGTTTACAGAGCTGAGCATTGGTGACAGGGTCTGACAT GGTCAGTCTACTAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAG CTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGG CCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCA TTTTGTCTGACTAGGTGTCC >OriGene 5' read for NM_000840 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTTTTGTGTCGGATGAG GAGGACCAACCATGAGCCAGAGCCCGGGTGCAGGCTCACCGCCGCCGCTGCCACCGCGGT CAGCTCCAGTTCCTGCCAGGAGTTGTCGGTGCGAGGAATTTTGTGACAGGCTCTGTTAGT CTGTTCCTCCCTTATTTGAAGGACAGGCCAAAGATCCAGTTTGGAAATGAGAGAGGACTA GCATGACACATTGGCTCCACCATTGATATCTCCCAGAGGTACAGAAACAGGATTCATGAA GATGTTGACAAGACTGCAAGTTCTTACCTTAGCTTTGTTTTCAAAGGGATTTTTACTCTC TTTAGGGGACCATAACTTTCTAAGGAGAGAGATTAAAATAGAAGGTGACCTTGTTTTAGG GGGCCTGTTTCCTATTAACGAAAAAGGCACTGGAACTGAAGAATGTGGGCGAATCAATGA AGACCGAGGGATTCAACGCCTGGAAGCCATGTTGTTTGCTATTGATGAAATCAACAAAGA TGATTACTTGCTACCAGGAGTGAAGTTGGGTGTTCACATTTTGGATACATGTTCAAGGGA TACCTATGCATTGGAGCAATCACTGGAGTTTGTCAGGGCATCTTTGACAAAAGTGGATGA AGCTGAGTATATGTGTCCTGATGGATCCTATGCCATTCAAGAAACATCCCACTTCTCATT GCAGGNGTCATTGGNTGGCTCTTATAGCAGTGTTTCCATACAGGTGCANACCTGCTGCGG CTCTTNCAGATCCCTCAGATCAGCTACGCATTCACCAGCGCCAAACTCAGTGATNAGTCG CGCTATGATTACTTTGNCAGNACCGTGCCCCCCGACTTCTACCAGCCAAAGCCTGGGCTG AATC >OriGene 3' read for NM_000840 unedited
TTTTAAAAAATTTTTCTTTGAACCGCGGNCCCGCATTCTANNGATCGATTTTTTTTTTTT TTTTTTGGTTTTTTTTTTTTGGTTTTTTTTTTTGGTTTTTAATAAACTGACCATGTCAAA CCCTGTCACCAATGCTCAACTCTGTAAACAATGGTTATTTCCATGTTCTGGGGGAATTGT TAATAATAGGGGCACTAAACTCAACCTAAAAAGTTCTAACACATCACTATATACAGTCCT CAAAAATAATTTATCGTACTGGTTCTAAAAAAAGGTACTAAGGGTGGTCTTTTGCTCTGT TTCCATATTCTGGAGCTGCACGTGAGCACTTTTGTCTAACAGTCTAAAAACACAAGAACT GAACTGTCATTCACAATCACAGAAATGAAGTGGTGGAGTCAAGGACTTTCCGCCCATTGC ACACCGTTGGCACATAACTGCCTGCAAAGGACTGAAAGTATGTGGTCCAATTTCACTGAC ACTAACCTGTTGAGGGCATCCTGTGTGTGACAACTTTCTTCTGGGGTGAAAACAGATATG GGAACCTGGGTGCAAACAAACACCCAGACCACAAACCCCTCAGGCTGACAAAAATGCCAT GGGTTGCCCCTGCCCCTTTATCACTTGATGCCCCTAAAATTANGGAGGAAGGCCACCCAA GATGCCCCTGGGGTCCTTGGAAAACCTTGACTTACCTTCTTGAAATTTTTGGGCCCTCCC CCTTTTGAAGGCGTCCCCGGGATAAAAACCCCCGAACCCCTTTTTGGTAAAAAAAAAACC ATGCGGGAATTTTGCAATGCTTTTAGAAAACCTGTTCCCCTTTTTTGCAGGTAACCCCTC TGGCCGGGGCTCCAGGTGACCCCCCACCCCCCTCATTTGCCCCCGATAAACCCCCCCCAT AAACCTGACACGGGGCTGAAAATTGGCCCTTACCCCCTTTTTCCCCTAAAAAAGGGGAAA AATTTGTTTGAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000840 |
| Insert Size | 3220 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000840.2, NP_000831.2 |
| RefSeq Size | 4260 bp |
| RefSeq ORF | 2640 bp |
| Locus ID | 2913 |
| UniProt ID | Q14832 |
| Domains | 7tm_3, ANF_receptor |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207379 | GRM3 (Myc-DDK-tagged)-Human glutamate receptor, metabotropic 3 (GRM3) |
CNY 6,440.00 |
|
| RC207379L1 | Lenti ORF clone of Human glutamate receptor, metabotropic 3 (GRM3), Myc-DDK-tagged |
CNY 8,840.00 |
|
| RC207379L2 | Lenti ORF clone of Human glutamate receptor, metabotropic 3 (GRM3), mGFP tagged |
CNY 9,030.00 |
|
| RC207379L3 | Lenti ORF clone of Human glutamate receptor, metabotropic 3 (GRM3), Myc-DDK-tagged |
CNY 8,840.00 |
|
| RC207379L4 | Lenti ORF clone of Human glutamate receptor, metabotropic 3 (GRM3), mGFP tagged |
CNY 8,840.00 |
|
| RG207379 | GRM3 (tGFP-tagged) - Human glutamate receptor, metabotropic 3 (GRM3) |
CNY 8,040.00 |
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