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GALNS (NM_000512) Human Untagged Clone
CAT＃: SC119830
GALNS (untagged)-Human galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS)
CNY 3,896.00
| Cited in 2 publications. |
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GalN6S; GALNAC6S; GAS; MPS4A |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119830 sequence for NM_000512 edited (data generated by NextGen Sequencing)
ATGGCGGCGGTTGTCGCGGCGACGAGGTGGTGGCAGCTGTTGCTGGTGCTCAGCGCCGCG GGGATGGGGGCCTCGGGCGCCCCGCAGCCCCCCAACATCCTGCTCCTGCTCATGGACGAC ATGGGATGGGGTGACCTCGGGGTGTATGGAGAGCCCTCCAGAGAGACCCCGAATTTGGAC CGGATGGCTGCAGAAGGGCTGCTTTTCCCAAACTTCTATTCTGCCAACCCTCTGTGCTCG CCATCGAGGGCGGCACTGCTCACAGGACGGCTACCCATCCGCAATGGCTTCTACACCACC AACGCCCATGCCAGAAACGCCTACACACCGCAGGAGATTGTGGGCGGCATCCCAGACTCG GAGCAGCTCCTGCCGGAGCTTCTGAAGAAGGCCGGCTACGTCAGCAAGATTGTCGGCAAG TGGCATCTGGGTCACAGGCCCCAGTTCCACCCCCTGAAGCACGGATTTGATGAGTGGTTT GGATCCCCCAACTGCCACTTTGGACCTTATGACAACAAGGCCAGGCCCAACATCCCTGTG TACAGGGACTGGGAGATGGTTGGCAGATATTATGAAGAATTTCCTATTAATCTGAAGACG GGGGAAGCCAACCTCACCCAGATCTACCTGCAGGAAGCCCTGGACTTCATTAAGAGACAG GCACGGCACCACCCCTTTTTCCTCTACTGGGCTGTCGACGCCACGCACGCACCCGTCTAT GCCTCCAAACCCTTCTTGGGCACCAGTCAGCGAGGGCGGTATGGAGACGCCGTCCGGGAG ATTGATGACAGCATTGGGAAGATACTGGAGCTCCTCCAAGACCTGCACGTCGCGGACAAC ACCTTCGTCTTCTTCACGTCGGACAACGGCGCTGCCCTCATTTCCGCCCCCGAACAAGGT GGCAGCAACGGCCCCTTTCTGTGTGGGAAGCAGACCACGTTTGAAGGAGGGATGAGGGAG CCTGCCCTCGCATGGTGGCCAGGGCACGTCACTGCAGGCCAGGTGAGCCACCAGCTGGGC AGCATCATGGACCTCTTCACCACCAGCCTGGCCCTTGCGGGCCTGACGCCGCCCAGCGAC AGGGCCATTGATGGCCTCAACCTCCTCCCCACCCTCCTGCAGGGCCGGCTGATGGACAGG CCTATCTTCTATTACCGTGGCGACACGCTGATGGCGGCCACCCTCGGGCAGCACAAGGCT CACTTCTGGACCTGGACCAACTCCTGGGAGAACTTCAGACAGGGCATTGATTTCTGCCCT GGGCAGAACGTTTCAGGGGTCACAACTCACAATCTGGAAGACCACACGAAGCTGCCCCTG ATCTTCCACCTGGGACGGGACCCAGGGGAGAGGTTCCCCCTCAGCTTTGCCAGCGCCGAG TACCAGGAGGCCCTCAGCAGGATCACCTCGGTCGTCCAGCAGCACCAGGAGGCCTTGGTC CCCGCGCAGCCCCAGCTCAACGTGTGCAACTGGGCGGTCATGAACTGGGCACCTCCGGGC TGTGAAAAGTTAGGGAAGTGTCTGACACCTCCAGAATCCATTCCCAAGAAGTGCCTCTGG TCCCACTAG Clone variation with respect to NM_000512.4 >OriGene 5' read for NM_000512 unedited
CACATTTTGTAATACGACTCACTATTAGGGCGGCCGCGAATTCGCACGAGGGGCCGGAGG GCCGGCGGACGCTCGCTAGGTCGGCTCGCTGGCCGGGGCTCCGCGGCTCCCGTGGTTGCC ATGGCGGCGGTTGTCGCGGCGACGAGGTGGTGGCAGCTGTTGCTGGTGCTCAGCGCCGCG GGGATGGGGGCCTCGGGCGCCCCGCAGCCCCCCAACATCCTGCTCCTGCTCATGGACGAC ATGGGATGGGGTGACCTCGGGGTGTATGGAGAGCCCTCCAGAGAGACCCCGAATTTGGAC CGGATGGCTGCAGAAGGGCTGCTTTTCCCAAACTTCTATTCTGCCAACCCTCTGTGCTCG CCATCGAGGGCGGCACTGCTCACAGGACGGCTACCCATCCGCAATGGCTTCTACACCACC AACGCCCATGCCAGAAACGCCTACACACCGCAGGAGATTGTGGGCGGCATCCCAGACTCG GAGCAGCTCCTGCCGGAGCTTCTGAAGAAGGCCGGCTACGTCAGCAAGATTGTCGGCAAG TGGCATCTGGGTCACAGGCCCCAGTTCCACCCCCTGAAGCACGGATTTGATGAGTGGTTT GGATCCCCCAACTGCCACTTTGGACCTTATGACAACAAGGCCAGGCCCAACATCCCTGTG TACAGGGACTGNGAGATGGTTGGCAGATATTATGAAGAATTTCCTATTTAATCTGAGACG GGGNAAGCCNACCTCACCCAGATCTACCCTGCAGAAGCCCTGGACTTCATTTAGAGACAG GCACGGCACCACCCCCTTTTTCCTCTACTGGGCTGTCGACGCCACGCACGCACCCGTCTT TGCCTCCAAACCTTCTTGGGCACAGTCANCGAGGGCGGTTTGGAAACCCCGTTCCCGGAG ATTGATGAAGCATGNGGGAGGAACTGGGACTCCTCCAGACCTGCACCGTGCGGGCACCCC T >OriGene 3' read for NM_000512 unedited
TCCTGCCTCCCGCTTNTATTTCTAAATAACATAGTTACAATGATAAGAAGCTACACGCCT CCCTCATAATTANGCGTCCAGGNGAAATTCCTTGTGGACAAAGGACAGACGGAACTGGAA GTCATCCCTCTGGGGCTCCCCTGAGACAAACGCTTATATGATTGCCCCGTTCCCTTACTG TTTACATAAAAATGCGGATTCACTGGGCCAGACTCAATCGTGTATTCAGTGGAAGGCTGA CTGAACCAATGTACGCCATACACATACTGATCTTGTGTCTCCCTAAGATGTATAAAGGCA AACTGTATCCCCAGCCACCTCAGGCACCTGTTGTCAGGACCTCCTGAGGCTGTCACAGGT GCATCCTTAACCTTGGCAAAATAAACTGAGACTGGTCTCAGATATTTGGGGTTCACAAAG GCGTGAGACGGCAGGGTCCTGAGGTCTGAGGCGCCGTGGGCGAGGAGGAGGGTCCTGAAA TCTGAGGCGCCGTGGGCGAGGAGGAGGGCCAAGCACACGCCAGGGTCAGGTCCTGGGCAG GTGGAATTGTGCAGTCCCCCTGCGTCTGCAGGTGCTGTCTGTCTGGCTTGGGCAGGGTTG GGGGAGGACCGAGGCCAGAGCCATCCTTCCTCCAGGCACTTGCAGGGCCAACCGGAGATT CTAGGCCTGGCCTGAGTCTGCGCAGGTGCTAGTGGGACCAGAGGCACTTCTTGGGAATGG ATCCNNTGAGTGTCAGACACTTCCCTAACTTTTCACAGCCCCGGAGGTGCCCAGTTCATG ACCGNCCAGTTGCACACGTTTGAGCTGGGGCTGCCGCGGGACCAAAGCCTCCTGGTGCTG CTGGACGACCGAAGTGATCCTGCTGGAGGCCTCCTGGTACTCGGCGCTGGCAAGCTGAGG GGGAACTCTCCCCTGGTCCCGTCCAGGTGGAGATCAGGCCANTTCGGTGGCTTTAGATTG GAGTGGACCCTGAACTTCTGCAGGCAGAATAAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000512 |
| Insert Size | 2640 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000512.3, NP_000503.1 |
| RefSeq Size | 2390 bp |
| RefSeq ORF | 1569 bp |
| Locus ID | 2588 |
| UniProt ID | P34059 |
| Domains | Sulfatase |
| Protein Families | Druggable Genome |
| Protein Pathways | Glycosaminoglycan degradation, Lysosome, Metabolic pathways |
| Gene Summary | This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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AGPAT6 Is a Novel Microsomal Glycerol-3-phosphate Acyltransferase
,Yan Qun Chen, Ming-Shang Kuo, Shuyu Li, Hai H. Bui, David A. Peake, Philip E. Sanders, Stefan J. Thibodeaux, Shaoyou Chu, Yue-Wei Qian, Yang Zhao, David S. Bredt, David E. Moller, Robert J. Konrad, Anne P. Beigneux, Stephen G. Young, and Guoqing Cao,
J. Biol. Chem. 2008; 283(15): p. 10048-10057
[GALNS]
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Distinct effects of N-acetylgalactosamine-4-sulfatase and galactose-6-sulfatase expression on chondroitin sulfates
,Sumit Bhattacharyya, Kumar Kotlo, Sagar Shukla, Robert S. Danziger, and Joanne K. Tobacman,
J. Biol. Chem., Feb 2008; 10.1074/jbc.M707967200.
[GALNS]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208708 | GALNS (Myc-DDK-tagged)-Human galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS) |
CNY 3,888.00 |
|
| RC208708L1 | Lenti ORF clone of Human galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS), Myc-DDK-tagged |
CNY 6,288.00 |
|
| RC208708L2 | Lenti ORF clone of Human galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS), mGFP tagged |
CNY 6,460.00 |
|
| RC208708L3 | Lenti ORF clone of Human galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC208708L4 | Lenti ORF clone of Human galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS), mGFP tagged |
CNY 6,288.00 |
|
| RG208708 | GALNS (tGFP-tagged) - Human galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS) |
CNY 5,488.00 |
|
| SC322674 | GALNS (untagged)-Human galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS) |
CNY 2,950.00 |
