GALNS (NM_000512) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC208708L4V
- LentiORF®
-
Lenti ORF particles, GALNS (mGFP-tagged) - Human galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS), 200ul, >10^7 TU/mL
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CNY 9,975.00
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规格
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Specifications
Product Data | |
Product Name | GALNS (NM_000512) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | GalN6S; GALNAC6S; GAS; MPS4A |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_000512 |
ORF Size | 1566 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC208708).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000512.3 |
RefSeq Size | 2380 bp |
RefSeq ORF | 1569 bp |
Locus ID | 2588 |
Domains | Sulfatase |
Protein Families | Druggable Genome |
Protein Pathways | Glycosaminoglycan degradation, Lysosome, Metabolic pathways |
MW | 58 kDa |
Gene Summary | This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq, Jul 2008] |
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