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NMDAR2B (GRIN2B) (NM_000834) Human Untagged Clone
CAT＃: SC119642
GRIN2B (untagged)-Human glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B)
CNY 10,160.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DEE27; EIEE27; GluN2B; hNR3; MRD6; NMDAR2B; NR2B; NR3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000834, the custom clone sequence may differ by one or more nucleotides
ATGAAGCCCAGAGCGGAGTGCTGTTCTCCCAAGTTCTGGTTGGTGTTGGCCGTCCTGGCCGTGTCAGGCA GCAGAGCTCGTTCTCAGAAGAGCCCCCCCAGCATTGGCATTGCTGTCATCCTCGTGGGCACTTCCGACGA GGTGGCCATCAAGGATGCCCACGAGAAAGATGATTTCCACCATCTCTCCGTGGTACCCCGGGTGGAACTG GTAGCCATGAATGAGACCGACCCAAAGAGCATCATCACCCGCATCTGTGATCTCATGTCTGACCGGAAGA TCCAGGGGGTGGTGTTTGCTGATGACACAGACCAGGAAGCCATCGCCCAGATCCTCGATTTCATTTCAGC ACAGACTCTCACCCCCATCCTGGGCATCCACGGGGGCTCCTCTATGATAATGGCAGATAAGGATGAATCC TCCATGTTCTTCCAGTTTGGCCCATCAATTGAACAGCAAGCTTCCGTAATGCTCAACATCATGGAAGAAT ATGACTGGTACATCTTTTCTATCGTCACCACCTATTTCCCTGGCTACCAGGACTTTGTAAACAAGATCCG CAGCACCATTGAGAATAGCTTTGTGGGCTGGGAGCTAGAGGAGGTCCTCCTACTGGACATGTCCCTGGAC GATGGAGATTCTAAGATCCAGAATCAGCTCAAGAAACTTCAAAGCCCCATCATTCTTCTTTACTGTACCA AGGAAGAAGCCACCTACATCTTTGAAGTGGCCAACTCAGTAGGGCTGACTGGCTATGGCTACACGTGGAT CGTGCCCAGTCTGGTGGCAGGGGATACAGACACAGTGCCTGCGGAGTTCCCCACTGGGCTCATCTCTGTA TCATATGATGAATGGGACTATGGCCTCCCCGCCAGAGTGAGAGATGGAATTGCCATAATCACCACTGCTG CTTCTGACATGCTGTCTGAGCACAGCTTCATCCCTGAGCCCAAAAGCAGTTGTTACAACACCCACGAGAA GAGAATCTACCAGTCCAATATGCTAAATAGGTATCTGATCAATGTCACTTTTGAGGGGAGGAATTTGTCC TTCAGTGAAGATGGCTACCAGATGCACCCGAAACTGGTGATAATTCTTCTGAACAAGGAGAGGAAGTGGG AAAGGGTGGGGAAGTGGAAAGACAAGTCCCTGCAGATGAAGTACTATGTGTGGCCCCGAATGTGTCCAGA GACTGAAGAGCAGGAGGATGACCATCTGAGCATTGTGACCCTGGAGGAGGCACCATTTGTCATTGTGGAA AGTGTGGACCCTCTGAGTGGAACCTGCATGAGGAACACAGTCCCCTGCCAAAAACGCATAGTCACTGAGA ATAAAACAGACGAGGAGCCGGGTTACATCAAAAAATGCTGCAAGGGGTTCTGTATTGACATCCTTAAGAA AATTTCTAAATCTGTGAAGTTCACCTATGACCTTTACCTGGTTACCAATGGCAAGCATGGGAAGAAAATC AATGGAACCTGGAATGGTATGATTGGAGAGGTGGTCATGAAGAGGGCCTACATGGCAGTGGGCTCACTCA CCATCAATGAGGAACGATCGGAGGTGGTCGACTTCTCTGTGCCCTTCATAGAGACAGGCATCAGTGTCAT GGTGTCACGCAGCAATGGGACTGTCTCACCTTCTGCCTTCTTAGAGCCATTCAGCGCTGACGTATGGGTG ATGATGTTTGTGATGCTGCTCATCGTCTCAGCCGTGGCTGTCTTTGTCTTTGAGTACTTCAGCCCTGTGG GTTATAACAGGTGCCTCGCTGATGGCAGAGAGCCTGGTGGACCCTCTTTCACCATCGGCAAAGCTATTTG GTTGCTCTGGGGTCTGGTGTTTAACAACTCCGTACCTGTGCAGAACCCAAAGGGGACCACCTCCAAGATC ATGGTGTCAGTGTGGGCCTTCTTTGCTGTCATCTTCCTGGCCAGCTACACTGCCAACTTAGCTGCCTTCA TGATCCAAGAGGAATATGTGGACCAGGTTTCTGGCCTGAGCGACAAAAAGTTCCAGAGACCTAATGACTT CTCACCCCCTTTCCGCTTTGGGACCGTGCCCAACGGCAGCACAGAGAGAAATATTCGCAATAACTATGCA GAAATGCATGCCTACATGGGAAAGTTCAACCAGAGGGGTGTAGATGATGCATTGCTCTCCCTGAAAACAG GGAAACTGGATGCCTTCATCTATGATGCAGCAGTGCTGAACTATATGGCAGGCAGAGATGAAGGCTGCAA GCTGGTGACCATTGGCAGTGGGAAGGTCTTTGCTTCCACTGGCTATGGCATTGCCATCCAAAAAGATTCT GGGTGGAAGCGCCAGGTGGACCTTGCTATCCTGCAGCTCTTTGGAGATGGGGAGATGGAAGAACTGGAAG CTCTCTGGCTCACTGGCATTTGTCACAATGAGAAGAATGAGGTCATGAGCAGCCAGCTGGACATTGACAA CATGGCAGGGGTCTTCTACATGTTGGGGGCGGCCATGGCTCTCAGCCTCATCACCTTCATCTGCGAACAC CTTTTCTATTGGCAGTTCCGACATTGCTTTATGGGTGTCTGTTCTGGCAAGCCTGGCATGGTCTTCTCCA TCAGCAGAGGTATCTACAGCTGCATCCATGGGGTGGCGATCGAGGAGCGCCAGTCTGTAATGAACTCCCC CACCGCAACCATGAACAACACACACTCCAACATCCTGCGCCTGCTGCGCACGGCCAAGAACATGGCTAAC CTGTCTGGTGTGAATGGCTCACCGCAGAGCGCCCTGGACTTCATCCGACGGGAGTCATCCGTCTATGACA TCTCAGAGCACCGCCGCAGCTTCACGCATTCTGACTGCAAATCCTACAACAACCCGCCCTGTGAGGAGAA CCTCTTCAGTGACTACATCAGTGAGGTAGAGAGAACGTTCGGGAACCTGCAGCTGAAGGACAGCAACGTG TACCAAGATCACTACCACCATCACCACCGGCCCCATAGTATTGGCAGTGCCAGCTCCATCGATGGGCTCT ACGACTGTGACAACCCACCCTTCACCACCCAGTCCAGGTCCATCAGCAAGAAGCCCCTGGACATCGGCCT CCCCTCCTCCAAGCACAGCCAGCTCAGTGACCTGTACGGCAAATTCTCCTTCAAGAGCGACCGCTACAGT GGCCACGACGACTTGATCCGCTCCGATGTCTCTGACATCTCAACCCACACCGTCACCTATGGGAACATCG AGGGCAATGCCGCCAAGAGGCGTAAGCAGCAATATAAGGACAGCCTGAAGAAGCGGCCTGCCTCGGCCAA GTCCCGCAGGGAGTTTGACGAGATCGAGCTGGCCTACCGTCGCCGACCGCCCCGCTCCCCTGACCACAAG CGCTACTTCAGGGACAAGGAAGGGCTACGGGACTTCTACCTGGACCAGTTCCGAACAAAGGAGAACTCAC CCCACTGGGAGCACGTAGACCTGACCGACATCTACAAGGAGCGGAGTGATGACTTTAAGCGCGACTCCGT CAGCGGAGGAGGGCCCTGTACCAACAGGTCTCACATCAAGCACGGGACGGGCGACAAACACGGCGTGGTC AGCGGGGTACCTGCACCTTGGGAGAAGAACCTGACCAACGTGGAGTGGGAGGACCGGTCCGGGGGCAACT TCTGCCGCAGCTGTCCCTCCAAGCTGCACAACTACTCCACGACGGTGACGGGTCAGAACTCGGGCAGGCA GGCGTGCATCCGGTGTGAGGCTTGCAAGAAAGCAGGCAACCTGTATGACATCAGTGAGGACAACTCCCTG CAGGAACTGGACCAGCCGGCTGCCCCAGTGGCGGTGACGTCAAACGCCTCCACCACTAAGTACCCTCAGA GCCCGACTAATTCCAAGGCCCAGAAGAAGAACCGGAACAAACTGCGCCGGCAGCACTCCTACGACACCTT CGTGGACCTGCAGAAGGAAGAAGCCGCCCTGGCCCCGCGCAGCGTAAGCCTGAAAGACAAGGGCCGATTC ATGGATGGGAGCCCCTACGCCCACATGTTTGAGATGTCAGCTGGCGAGAGCACCTTTGCCAACAACAAGT CCTCAGTGCCCACTGCCGGACATCACCACCACAACAACCCCGGCGGCGGGTACATGCTCAGCAAGTCGCT CTACCCTGACCGGGTCACGCAAAACCCTTTCATCCCCACTTTTGGGGACGACCAGTGCTTGCTCCATGGC AGCAAATCCTACTTCTTCAGGCAGCCCACGGTGGCGGGGGCGTCGAAAGCCAGGCCGGACTTCCGGGCCC TTGTCACCAACAAGCCGGTGGTCTCGGCCCTTCATGGGGCCGTGCCAGCCCGTTTCCAGAAGGACATCTG TATAGGGAACCAGTCCAACCCCTGTGTGCCTAACAACAAAAACCCCAGGGCTTTCAATGGCTCCAGCAAT GGGCATGTTTATGAGAAACTTTCTAGTATTGAGTCTGATGTCTGA >OriGene 5' read for NM_000834 unedited
GCATTTGTATACGACTCACTATTAGGGCGGCCGCGAATTCGCACGAGGTGGACATTCCCA ACATGCTCACTCCCTTAATCTGTCCGTCTAGAGGTTTGGCTTCTACAAACCAAGGGAGTC GACGAGTTGAAGATGAAGCCCAGAGCGGAGTGCTGTTCTCCCAAGTTCTGGTTGGTGTTG GCCGTCCTGGCCGTGTCAGGCAGCAGAGCTCGTTCTCAGAAGAGCCCCCCCAGCATTGGC ATTGCTGTCATCCTCGTGGGCACTTCCGACGAGGTGGCCATCAAGGATGCCCACGAGAAA GATGATTTCCACCATCTCTCCGTGGTACCCCGGGTGGAACTGGTAGCCATGAATGAGACC GACCCAAAGAGCATCATCACCCGCATCTGTGATCTCATGTCTGACCGGACGATCCAGGGG GTGGTGTTTGCTGATGACACAGACCAGGAAGCCATCGCCCAGATCCTCGATTTCATTTCA GCACAGACTCTCACCCCGATCCTGGGCATCCACGGGGGCTCCTCTATGATAATGCTAGAT AAGGATGAATCCTCCATGTTCTTCCAGTTTGGCCCATCAATTGAACAGCAAGCTTTCGTA ATGCTCAACATCATGGAAGAATATGACTGGTACATCTTTTCTATCGTCACCACCTATTTC CCTGGCTACCAGGACTTTGTAAACANGATCCGCAGCACCATTGAGAATAGCTTTGTGGGC CTGGAGCTAGAGGGAGTCCTCCTACTGGACATGTCCCTGGACGATGGAGATTCTAAGATC CAGCATCAGCTCAAGAAACTTCAAAGCCCCATCATTCTTCCTTACTGTACCAGAGAAGAG GCCCCTTACTCTTTTGAGTGGCCAACTCAGNAAGGCTGACTGGCTATTGCTACACGTGGA TCGTGCCCATCTGGTGGCAGGGGAATCAGACCCGTTGCTGCGGAGTTCCCACTGGCTCAT CTTGTTCATTG >OriGene 3' read for NM_000834 unedited
ATGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTATTCCTCATGGT ACAATCTGAGAGGGAAACAAGGTGTTGCAGGAAGGTAGAAGGGCTTCTACCAAGAGTGTT CACTCTGGGCTCAAGTCACATTCCCAGGGAGCCAGGCCCAAAGAGGTGGTGGAGGGTCCC TCTCTGCCCCCGTCTCCCATTTCCAAGTCTCTTCCCCTCTTTTCGTACCTCCAGAGCTGC ACTCATGGAGTGCAGCTCATTTCTCTTAAATGTCAAGCTCATTTCTCTTAACTGTCTGCT CTGTAGCAGTTGTAATCAGTTTTGGGGGGAAGAAGCCTGCTCGTCTAGCTTCAGGTTAAG TAAGAAGGGATCAAAGCATTGGAAACATCCCCCTCTCTCACTTACCCTACCATACACGAC TCCTTACTTCTTCAAAGGTGGCTTCGTTCTTCCCCAAACCTTGGCCAGTCGAGAGTCTAA ATGCTCAAAAGAGCTTTGTAGAATCTTTTGCTCCCAAGTGTGGGCAAAAGAATCATGGCT GTGAAAATTCGGCTTCCCTTTAGCCTTCCTGGAAAGTTCTTGGTTCAAACTGGTTGAAAC AATTGCCAACCACTGAGGACTTGTTTATGTACCTTGCTCTTGCAGGATTGCTCACCGCCT TTTTTTGTTTAGACCACAGAATCTTCTTTATCAAGAATTCTCATTCTCCTTATTTCACAA GATGAACGGAGACCCAGCCAAAATTCAGGCAATACATGGCCATCTCTGTCTGTATACTAG CCAAACAATCACACCTGCTTGGGGATTTCCAAAGAACCATCCCACAGAGCCAGGGTTGCC CTCTTCTTGAGGCACCTGGATAACACATGCGCCCAAGTCCCGCATGAACCCCACATGCCC GCCAAAATTCCACTGCTCTTGGNCCCCAGGACCGGGGGAACACTTACAACCGCACCTTTC ACGCGGCCACAGACCCACCTGTCCACCAGCGACTCTGTGTTC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000834 |
| Insert Size | 6250 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000834.2, NP_000825.1 |
| RefSeq Size | 6240 bp |
| RefSeq ORF | 4455 bp |
| Locus ID | 2904 |
| UniProt ID | Q13224 |
| Domains | lig_chan |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Huntington's disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Systemic lupus erythematosus |
| Gene Summary | This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223623 | GRIN2B (Myc-DDK-tagged)-Human glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B) |
CNY 15,232.00 |
|
| RC223623L1 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B), Myc-DDK-tagged |
CNY 17,632.00 |
|
| RC223623L2 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B), mGFP tagged |
CNY 17,632.00 |
|
| RC223623L3 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B), Myc-DDK-tagged |
CNY 17,632.00 |
|
| RC223623L4 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B), mGFP tagged |
CNY 17,632.00 |
|
| RG223623 | GRIN2B (tGFP-tagged) - Human glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B) |
CNY 16,832.00 |
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