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HLA-DPB1 (NM_002121) Human Untagged Clone
CAT＃: SC118846
HLA (untagged)-Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DPB1; HLA-DP; HLA-DP1B; HLA-DPB |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118846 sequence for NM_002121 edited (data generated by NextGen Sequencing)
ATGATGGTTCTGCAGGTTTCTGCGGCCCCCCGGACAGTGGCTCTGACGGCGTTACTGATG GTGCTGCTCACATCTGTGGTCCAGGGCAGGGCCACTCCAGAGAATTACCTTTTCCAGGGA CGGCAGGAATGCTACGCGTTTAATGGGACACAGCGCTTCCTGGAGAGATACATCTACAAC CGGGAGGAGTTCGCGCGCTTCGACAGCGACGTGGGGGAGTTCCGGGCGGTGACGGAGCTG GGGCGGCCTGCTGCGGAGTACTGGAACAGCCAGAAGGACATCCTGGAGGAGAAGCGGGCA GTGCCGGACAGGATGTGCAGACACAACTACGAGCTGGGCGGGCCCATGACCCTGCAGCGC CGAGTCCAGCCTAGGGTGAATGTTTCCCCCTCCAAGAAGGGGCCCTTGCAGCACCACAAC CTGCTTGTCTGCCACGTGACGGATTTCTACCCAGGCAGCATTCAAGTCCGATGGTTCCTG AATGGACAGGAGGAAACAGCTGGGGTCGTGTCCACCAACCTGATCCGTAATGGAGACTGG ACCTTCCAGATCCTGGTGATGCTGGAAATGACCCCCCAGCAGGGAGATGTCTACACCTGC CAAGTGGAGCACACCAGCCTGGATAGTCCTGTCACCGTGGAGTGGAAGGCACAGTCTGAT TCTGCCCGGAGTAAGACATTGACGGGAGCTGGGGGCTTCGTGCTGGGGCTCATCATCTGT GGAGTGGGCATCTTCATGCACAGGAGGAGCAAGAAAGTTCAACGAGGATCTGCATAA Clone variation with respect to NM_002121.5 >OriGene 5' read for NM_002121 unedited
TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTTTTCATTTTGCC ATCCTTTTCCAGCTCCATGATGGTTCTGCAGGTTTCTGCGGCCCCCCGGACAGTGGCTCT GACGGCGTTACTGATGGTGCTGCTCACATCTGTGGTCCAGGGCAGGGCCACTCCAGAGAA TTACCTTTTCCAGGGACGGCAGGAATGCTACGCGTTTAATGGGACACAGCGCTTCCTGGA GAGATACATCTACAACCGGGAGGAGTTCGCGCGCTTCGACAGCGACGTGGGGGAGTTCCG GGCGGTGACGGAGCTGGGGCGGCCTGCTGCGGAGTACTGGAACAGCCAGAAGGACATCCT GGAGGAGAAGCGGGCAGTGCCGGACAGGATGTGCAGACACAACTACGAGCTGGGCGGGCC CATGACCCTGCAGCGCCGAGTCCAGCCTAGGGTGAATGTTTCCCCCTCCAAGAAGGGGCC CTTGCAGCACCACAACCTGCTTGTCTGCCACGTGACGGATTTCTACCCAGGCAGCATTCA AGTCCGATGGTTCCTGAATGGACAGGAGGAAACAGCTGGGGTCGTGTCCACCAACCTGAT CCGTAATGGAGACTGGACCTTCCAGATCCTGGTGATGCTGGAAATGACCCCCCAGCAGGG AGATGTCTACACCTGCCAAGTGGAGCACACCAGCCTGGATAGTCCTGTCACCGTGGAGTG GAAGGCACAGTCTGATTCTGCCCGGNAGTAGACATTGACGGGAGCTGGGGGCTTCGTGCT GGGGCTCATCATCTGTGGAGTGGGCATCTTCATGCACAGGNAGGAGCAGAAAGNTTCACG AGGNATCTGCATAACAGGGNTCCTGAGCTCACTGAAAAGACTATTGTGCCTTTAGNAAAG CATTNGCTGTGTTNCGNTAGCATCTGGCTNCC >OriGene 3' read for NM_002121 unedited
CGGCCGCTTTTAGNATCGAGTTTTTTTTTTTTTTTTTTATGTTGGGTTTTGATTATTTGT GGTGCTAAAAAAAAGGAACATGGTTGGAGGCCCAGTGAGAGAAACAGTGCTTTGAATCAA AGAGCAGAATGATAGAAACTGACTTCAGAGCAACTTCTTGGCAGCAGTATCCAATTTGGA AGTTGAAGGTCTGTCCTGGAGCCAGATGCTAACGAAACACAGCAAATGCTTTTCCTAAGG CACAATAGTCTTTTCAGTGAGCTCAGGAACCCTGTTTATGCAGATCCTCGTTGAACTTTC TTGCTCCTCCTGTGCATGAAGATGCCCACTCCACAGATGATGAGCCCCAGCACGAAGCCC CCAGCTCCCGTCAATGTCTTACTCCGGGCAGAATCAGACTGTGCCTTCCACTCCACGGTG ACAGGACTATCCAGGCTGGTGTGCTCCACTTGGCAGGTGTAGACATCTCCCTGCTGGGGG GTCATTTCCAGCATCACCAGGATCTGGAAGGTCCAGTCTCCATTACGGATCAGGTTGGTG GACACGACCCCAGCTGTTTCCTCCTGTCCATTCAGGAACCATCGGACTTGAATGCTGCCT GGGTAGAAATCCGTCACGTGGCAGACAAGCAGGTTGTGGTGCTGCAAGGGCCCCTTCTTG GAGGGGGAAACATTCACCCTAGGCTGGACTCGGCGCTGCAGGGTCATGGGCCCGCCCAGC TCGTAGTTGTGTCTGCACATCCTGTCCGGCACTGCCCGCTTCTCCTCCAGNATGTCCTTN CTGGNCTGTTCAGTACTNCGCAGCAGGCCGCCCCAGCTTCGTCACCGNCCGGAACTCCNC CACGTCGCTGTCNGAGCGCGCGAACTCCTCCCGGNTGTAGATGTATCTCTTCAGAAAGCG CTGNNGTCCATTAAACGCGTAGCATTCCTGCCGTCCCTGGNAAANGTANTNCTCTGNAGT GGCCCTGCCCTGNACCCAGNAGTGAGCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002121 |
| Insert Size | 1050 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002121.4, NP_002112.3 |
| RefSeq Size | 1501 bp |
| RefSeq ORF | 777 bp |
| Locus ID | 3115 |
| UniProt ID | P04440 |
| Domains | MHC_II_beta, ig, IGc1 |
| Protein Families | Transmembrane |
| Protein Pathways | Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Type I diabetes mellitus, Viral myocarditis |
| Gene Summary | HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204966 | HLA (Myc-DDK-tagged)-Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1) |
CNY 2,400.00 |
|
| RC204966L1 | Lenti ORF clone of Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC204966L2 | Lenti ORF clone of Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), mGFP tagged |
CNY 5,890.00 |
|
| RC204966L3 | Lenti ORF clone of Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204966L4 | Lenti ORF clone of Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), mGFP tagged |
CNY 5,890.00 |
|
| RG204966 | HLA (tGFP-tagged) - Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1) |
CNY 4,000.00 |
|
| SC320914 | HLA (untagged)-Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1) |
CNY 2,400.00 |
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