HLA-DPB1 (NM_002121) Human Tagged ORF Clone
CAT#: RG204966
- TrueORF®
HLA (tGFP-tagged) - Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1)
ORF Plasmid: DDK
"NM_002121" in other vectors (7)
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CNY 4,000.00
CNY 4,370.00
CNY 1,000.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | DPB1; HLA-DP; HLA-DP1B; HLA-DPB |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG204966 representing NM_002121
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTTCTGCAGGTTTCTGCGGCCCCCCGGACAGTGGCTCTGACGGCGTTACTGATGGTGCTGCTCACAT CTGTGGTCCAGGGCAGGGCCACTCCAGAGAATTACGTGCACCAGTTACGGCAGGAATGCTACGCGTTTAA TGGGACACAGCGCTTCCTGGAGAGATACATCTACAACCGGGAGGAGTTCGTGCGCTTCGACAGCGACGTG GGGGAGTTCCGGGCGGTGACGGAGCTGGGGCGGCCTGATGAGGACTACTGGAACAGCCAGAAGGACATCC TGGAGGAGGAGCGGGCAGTGCCGGACAGGATGTGCAGACACAACTACGAGCTGGACGAGGCCGTGACCCT GCAGCGCCGAGTCCAGCCTAGGGTGAATGTTTCCCCCTCCAAGAAGGGGCCCTTGCAGCACCACAACCTG CTTGTCTGCCACGTGACGGATTTCTACCCAGGCAGCATTCAAGTCCGATGGTTCCTGAATGGACAGGAGG AAACAGCTGGGGTCGTGTCCACCAACCTGATCCGTAATGGAGACTGGACCTTCCAGATCCTGGTGATGCT GGAAATGACCCCCCAGCAGGGAGATGTCTACACCTGCCAAGTGGAGCACACCAGCCTGGATAGTCCTGTC ACCGTGGAGTGGAAGGCACAGTCTGATTCTGCCCGGAGTAAGACATTGACGGGAGCTGGGGGCTTCGTGC TGGGGCTCATCATCTGTGGAGTGGGCATCTTCATGCACAGGAGGAGCAAGAAAGTTCAACGAGGATCTGC A AGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG204966 representing NM_002121
Red=Cloning site Green=Tags(s) MVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYVHQLRQECYAFNGTQRFLERYIYNREEFVRFDSDV GEFRAVTELGRPDEDYWNSQKDILEEERAVPDRMCRHNYELDEAVTLQRRVQPRVNVSPSKKGPLQHHNL LVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPV TVEWKAQSDSARSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA SGPTRTRRLE - GFP Tag - V |
Restriction Sites | SgfI-RsrII Cloning Scheme for this gene Plasmid Map |
ACCN | NM_002121 |
ORF Size | 771 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_002121.4, NP_002112.3 |
RefSeq Size | 1501 bp |
RefSeq ORF | 777 bp |
Locus ID | 3115 |
UniProt ID | P04440 |
Domains | MHC_II_beta, ig, IGc1 |
Protein Families | Transmembrane |
Protein Pathways | Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Type I diabetes mellitus, Viral myocarditis |
Gene Summary | HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204966 | HLA (Myc-DDK-tagged)-Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1) |
CNY 2,400.00 |
|
RC204966L1 | Lenti ORF clone of Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), Myc-DDK-tagged |
CNY 4,800.00 |
|
RC204966L2 | Lenti ORF clone of Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), mGFP tagged |
CNY 5,890.00 |
|
RC204966L3 | Lenti ORF clone of Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204966L4 | Lenti ORF clone of Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), mGFP tagged |
CNY 5,890.00 |
|
SC118846 | HLA (untagged)-Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1) |
CNY 2,400.00 |
|
SC320914 | HLA (untagged)-Human major histocompatibility complex, class II, DP beta 1 (HLA-DPB1) |
CNY 2,400.00 |
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