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Karyopherin beta 3 (IPO5) (NM_002271) Human Untagged Clone
CAT＃: SC118726
IPO5 (untagged)-Human importin 5 (IPO5)
CNY 7,648.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IMB3; imp5; KPNB3; Pse1; RANBP5 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_002271, the custom clone sequence may differ by one or more nucleotides
ATGCCTGAGGATCAAGTTGGAAAACTAGAAGCAACAGAAAACACAATAAGCGCAATGGCGGCGGCCGCGG CGGAGCAGCAACAGTTCTACCTGCTCCTGGGAAACCTGCTCAGCCCCGACAATGTGGTCCGGAAACAGGC AGAGGAAACCTATGAGAATATCCCAGGCCAGTCAAAGATCACATTCCTCTTACAAGCCATCAGAAATACA ACAGCTGCTGAAGAGGCTAGACAAATGGCCGCCGTTCTCCTAAGACGTCTCTTGTCCTCTGCATTTGATG AAGTCTATCCAGCACTTCCCTCTGATGTTCAGACTGCCATCAAGAGTGAGCTACTCATGATTATTCAGAT GGAAACACAATCTAGCATGAGGAAAAAAGTTTGTGATATTGCGGCAGAACTGGCCAGGAATTTAATAGAT GAGGATGGCAATAACCAGTGGCCCGAAGGTTTGAAGTTCCTTTTTGATTCAGTCAGCTCTCAAAATGTGG GACTGCGGGAAGCTGCCCTTCACATTTTCTGGAACTTTCCTGGAATTTTTGGGAACCAGCAACAACACTA TTTAGATGTCATCAAACGAATGTTAGTTCAGTGTATGCAAGATCAGGAACACCCGTCGATCAGGACGTTA TCTGCTAGAGCTACAGCTGCATTTATACTTGCAAATGAGCATAATGTTGCTCTGTTCAAACATTTTGCAG ACTTGCTACCGGGATTCCTACAGGCGGTAAATGACTCGTGCTACCAGAATGATGATTCTGTCCTAAAATC CCTCGTTGAGATTGCAGATACTGTTCCAAAGTATTTGCGTCCTCACTTGGAAGCAACTCTACAGCTAAGT CTAAAGTTGTGTGGAGACACTAGCCTCAACAATATGCAACGCCAGCTTGCCCTTGAAGTGATCGTCACCC TCTCTGAGACTGCAGCTGCTATGTTAAGAAAACATACCAATATTGTTGCACAGACTATTCCTCAGATGTT AGCAATGATGGTTGATTTGGAAGAAGATGAGGACTGGGCAAATGCAGATGAACTAGAAGATGATGATTTT GACAGCAATGCAGTTGCAGGCGAGAGTGCTCTAGATCGAATGGCTTGCGGACTTGGTGGAAAGCTCGTTC TGCCGATGATCAAGGAACACATTATGCAAATGCTTCAAAATCCTGACTGGAAATACCGGCATGCAGGATT GATGGCCTTATCTGCCATTGGTGAAGGGTGCCACCAGCAAATGGAAGGAATTCTAAATGAGATCGTAAAT TTTGTTTTACTTTTTCTCCAGGATCCTCATCCAAGAGTAAGGTATGCAGCCTGTAATGCCGTGGGACAGA TGGCTACAGATTTTGCACCTGGTTTCCAAAAGAAATTTCATGAGAAGGTGATTGCAGCTCTGCTGCAGAC CATGGAAGACCAAGGCAATCAACGTGTGCAGGCCCATGCAGCTGCTGCCCTCATTAACTTTACTGAAGAC TGTCCCAAGTCACTACTTATTCCATACTTGGATAATTTGGTGAAACATCTGCATTCCATTATGGTACTGA AGCTTCAAGAGCTGATTCAGAAAGGCACCAAGTTAGTTTTGGAACAAGTTGTGACATCCATTGCATCAGT TGCCGATACTGCAGAAGAAAAATTTGTCCCCTACTATGATTTATTTATGCCATCACTGAAGCACATCGTT GAGAATGCGGTTCAAAAAGAACTGAGACTTCTGAGAGGAAAAACTATTGAATGCATTAGCCTCATTGGTC TGGCTGTTGGGAAGGAAAAATTCATGCAGGATGCATCAGATGTGATGCAGCTTTTGTTAAAGACCCAGAC AGACTTCAATGATATGGAAGATGATGATCCTCAGATCTCTTACATGATCTCAGCATGGGCCAGAATGTGC AAAATCCTTGGAAAAGAATTTCAGCAATACCTTCCAGTGGTTATGGGGCCTTTAATGAAGACGGCTTCAA TTAAGCCCGAAGTAGCCCTTTTAGATACCCAAGACATGGAGAATATGAGTGATGATGATGGTTGGGAATT TGTGAACCTTGGAGATCAGCAAAGCTTTGGTATTAAAACTGCAGGACTAGAAGAAAAATCAACTGCTTGC CAGATGTTGGTTTGCTATGCTAAGGAGTTAAAGGAAGGCTTTGTGGAGTACACCGAACAGGTTGTCAAAC TGATGGTCCCTTTACTGAAATTTTATTTCCACGATGGTGTTCGAGTGGCAGCAGCGGAATCCATGCCTCT TCTCCTGGAGTGTGCAAGAGTCCGTGGTCCTGAGTATCTCACACAGATGTGGCATTTTATGTGTGATGCT CTAATTAAGGCCATTGGTACAGAACCAGATTCAGACGTCCTCTCAGAAATAATGCATTCTTTTGCAAAGT GCATTGAAGTAATGGGAGATGGATGCCTTAATAATGAACACTTTGAAGAACTGGGAGGTATATTGAAAGC AAAGCTTGAAGAACATTTTAAAAATCAAGAATTACGACAAGTTAAAAGACAAGATGAAGACTATGATGAA CAGGTCGAAGAGTCACTACAAGATGAGGATGATAATGATGTTTATATTCTGACCAAAGTGTCAGATATTT TACACTCAATATTCAGTAGCTACAAAGAAAAGGTGTTACCATGGTTTGAACAGCTGCTTCCATTAATTGT CAACCTCATTTGTCCACATAGACCATGGCCAGACAGACAATGGGGATTATGCATCTTTGATGATGTCATA GAACACTGTAGTCCAGCCTCATTTAAATACGCAGAATATTTCTTAAGACCAATGCTCCAATATGTATGTG ACAACAGCCCAGAAGTCAGGCAAGCAGCTGCATATGGCCTGGGAGTCATGGCACAGTACGGTGGAGATAA TTATCGCCCTTTTTGTACAGAAGCACTTCCCCTGCTGGTAAGAGTTATTCAGTCTGCGGATTCTAAGACC AAAGAAAATGTCAATGCTACAGAGAACTGCATCTCAGCAGTAGGGAAAATCATGAAGTTCAAGCCTGACT GTGTAAACGTTGAAGAGGTCCTTCCACACTGGTTGTCTTGGCTTCCACTACATGAAGATAAAGAAGAAGC TGTTCAGACTTTCAATTATCTGTGTGACCTGATTGAAAGTAATCATCCAATTGTTCTTGGCCCAAACAAT ACCAATCTGCCCAAAATATTTAGTATAATTGCGGAAGGAGAAATGCACGAGGCAATTAAACATGAAGATC CTTGTGCCAAACGTCTGGCCAATGTCGTTCGCCAAGTACAGACTTCTGGAGGACTGTGGACTGAGTGCAT AGCACAGCTCAGTCCTGAGCAGCAGGCCGCCATTCAGGAGCTCCTGAACTCTGCGTGA >OriGene 5' read for NM_002271 unedited
CGGCCGCGAATTCGGCACCAGCGGCCGCGGCGGAGTGAGAGGCCGCGAGGCCCCGCCCCG TCCTCCCCTTTCCCCTTTGCCCCGCCCTTCCCGCGCGGCCCCCCGCAAGCCCCGCGCCGC CGCTGGTGCCGGTCCCCGCGCTGGGCCCGCCCCCGCCCCTCCCGCGGCCCGCGAGCGCGC CTCACGGCTCCTGTCTCCCCTCCCTCCTTCTCTCTCACGCCTAGCGCAATGGCGGCGGCC GCGGCGGAGCAGCAACAGTTCTACCTGCTCCTGGGAAACCTGCTCAGCCCCGACAATGTG GTCCGGAAACAGGCAGAGGAAACCTATGAGAATATCCCAGGCCAGTCAAAGATCACATTC CTCTTACAAGCCATCAGAAATACAACAGCTGCTGAAGAGGCTAGACAAATGGCCGCCGTT CTCCTAAGACGTCTCTTGTCCTCTGCATTTGATGAAGTCTATCCAGCACTTCCCTCTGAT GTTCAGACTGCCATCAAGAGTGAGCTACTCATGATTATTCAGATGGAAACACAATCTAGC ATGAGGAAAAAAGTTTGTGATATTGCGGCAGAACTGGCCAGGAATTTAATAGATGAGGAT GGCAATAACCAGTGGCCCGAAGGTTTGAAGTTCCTTTTTGATTCAGTCAGCTCTCAAAAT GTGGGACTGCGGGAAGCTGCCCTTCACATTNTCTGGAACTTTCCTGGNATT >OriGene 3' read for NM_002271 unedited
CCCCTTACTGTGCCACCGCGGCCGCATTTCACGACCGGGTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTAAGAAAAACCCTTCTATTTAAAATTCTGATCTATGCATAAAA TTCATTTTTATATTCCGGTTAAATTTAGCCCAAACTATAAAAAGGTTACCCCTGAAGTTT TCACCAGAAAGTCTATTAGGCAGGCCTTACAAACCTCTCCCCCCCCGCGGTCTTTTCCTG CTATGAGGTTAATCCCTACCGAAACATTCCCCCTTTTTACTGAAATTTTCAGTAACCAAC TTTACCCATACCCTTTATAACTAACCCCCCACACCGTCGGGGGCGGTCCTACCCCCATTC CCCTTCCCCACGCACCCCCTTACCCCCAACCTTTCTGCCCCGCCCCCACCAACCTCCCCT CCCACACTGCCTGCCCTTCCCTCCCCTCTCCCCCACCCCCCCCTCCCCACGGCCACGGTA TCCTCATTCTCCCTTCACCCGCCCCCACGGCCCCCCCCCCCTCCCTCACCCCTCCCCCCC CCCCCGCCACCCCCCCCCCCCCAACCCCTCCCCCCCCCGGGCCTCCCCTCCTTCCCCCCC ACATCCCTCTCCCCTCCCCCCCCCCCCCCCACCCCCCCCCACTCCTACCCGCCCCACAAC TCCCCCCCCCCCAACCCCCCCCCACCCCCCTCTTCTCATTCCTTTCCCCCAACTATCCCC CTCATACCCTTATCCTCACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCC CCCCCTCCCCCATCCCAGCCCCCATCCACCCCCCCCCCCCCTCCCCCCTCCCCCCCCCCC CTCCTCCTCCCCCCCCCCCCCCTCCTCTCCCCCTCCCCATTCACAACCCCACACTCCCTA CCCCGTCTTTCTCCTCCCCCCCCCCTCATCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002271 |
| Insert Size | 4470 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002271.2, NP_002262.2 |
| RefSeq Size | 6019 bp |
| RefSeq ORF | 3294 bp |
| Locus ID | 3843 |
| UniProt ID | O00410 |
| Protein Families | Druggable Genome |
| Gene Summary | Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage
,null,
The Journal of Cell Biology
,PubMed ID 35089308
[IPO5]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207221 | IPO5 (Myc-DDK-tagged)-Human importin 5 (IPO5) |
CNY 7,768.00 |
|
| RC207221L1 | Lenti-ORF clone of IPO5 (Myc-DDK-tagged)-Human importin 5 (IPO5) |
CNY 10,168.00 |
|
| RC207221L2 | Lenti-ORF clone of IPO5 (mGFP-tagged)-Human importin 5 (IPO5) |
CNY 13,020.00 |
|
| RC207221L3 | Lenti-ORF clone of IPO5 (Myc-DDK-tagged)-Human importin 5 (IPO5) |
CNY 13,020.00 |
|
| RC207221L4 | Lenti-ORF clone of IPO5 (mGFP-tagged)-Human importin 5 (IPO5) |
CNY 13,020.00 |
|
| RG207221 | IPO5 (tGFP-tagged) - Human importin 5 (IPO5) |
CNY 12,260.00 |
|
| SC318500 | IPO5 (untagged)-Human importin 5 (IPO5) |
CNY 10,450.00 |
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