CBX4 (NM_003655) Human Untagged Clone

CAT#: SC117841

CBX4 (untagged)-Human chromobox homolog 4 (CBX4)



  "NM_003655" in other vectors (6)

CNY 6,264.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


Rabbit polyclonal anti-PC2 antibody
    • 100 ug

CNY 8,025.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms NBP16; PC2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC117841 sequence for NM_003655 edited (data generated by NextGen Sequencing)
ATGGAGCTGCCAGCTGTTGGCGAGCACGTCTTCGCGGTGGAGAGCATCGAGAAGAAGCGG
ATCCGCAAGGGCAGAGTGGAGTATCTGGTGAAATGGAGAGGCTGGTCGCCCAAATATAAC
ACGTGGGAACCGGAGGAGAACATCCTGGACCCCAGGCTGCTGATCGCCTTCCAGAACAGG
GAACGGCAGGAGCAGCTGATGGGATATCGGAAGAGAGGGCCGAAGCCCAAACCGCTAGTG
GTGCAGGTGCCTACCTTTGCCCGTCGTTCCAATGTCCTGACCGGCCTCCAGGACTCCTCC
ACTGACAACCGTGCCAAGCTGGATTTGGGCGCGCAGGGGAAGGGCCAGGGGCATCAGTAC
GAGCTCAACAGCAAGAAGCACCACCAGTACCAGCCGCACAGCAAGGAGCGGGCGGGCAAG
CCCCCGCCGCCGGGCAAGAGCGGCAAGTACTACTACCAGCTCAACAGCAAGAAGCACCAC
CCCTACCAGCCCGACCCCAAAATGTACGACCTGCAGTACCAGGGCGGCCACAAGGAGGCG
CCCAGCCCCACCTGCCCGGACCTGGGGGCCAAGAGCCACCCGCCCGACAAGTGGGCGCAA
GGTGCGGGGGCCAAAGGCTACCTGGGGGCGGTGAAGCCCCTGGCCGGTGCGGCGGGTGCT
CCAGGCAAAGGCTCCGAGAAGGGCCCCCCCAACGGAATGATGCCGGCCCCCAAAGAGGCT
GTGACGGGCAACGGGATTGGGGGCAAGATGAAGATAGTCAAGAACAAGAACAAGAACGGA
CGCATCGTGATCGTGATGAGCAAATACATGGAGAACGGCATGCAGGCGGTGAAGATCAAG
TCCGGCGAGGTGGCAGAGGGGGAGGCTCGCTCCCCCAGCCACAAGAAGCGGGCAGCCGAC
GAGCGCCACCCTCCTGCCGACAGGACTTTTAAAAAGGCGGCGGGCGCAGAGGAGAAGAAG
GTGGAGGCGCCGCCCAAGAGGAGGGAGGAGGAGGTGTCCGGGGTTAGCGATCCGCAGCCC
CAGGATGCCGGCTCCCGCAAGCTGTCCCCGACCAAGGAGGCCTTTGGAGAGCAGCCCCTG
CAGCTCACCACCAAGCCCGACCTGCTTGCCTGGGACCCGGCCCGGAACACGCACCCGCCC
TCACACCACCCGCACCCGCACCCCCATCACCACCACCACCACCACCACCACCACCACCAC
GCCGTCGGCCTGAATCTCTCCCACGTGCGCAAGCGCTGCCTCTCCGAGACCCACGGCGAG
CGCGAGCCCTGCAAGAAGCGGCTGACTGCGCGCAGCATCAGCACCCCCACCTGCCTGGGG
GGCAGCCCAGCCGCTGAGCGCCCGGCCGACCTGCCACCAGCCGCCGCCCTCCCGCAGCCC
GAGGTCATCCTGCTAGACTCAGACCTGGATGAACCCATAGACTTGCGCTGCGTCAAGACG
CGCAGCGAGGCCGGGGAGCCGCCCAGCTCCCTCCAGGTGAAGCCCGAGACACCGGCGTCG
GCGGCGGTGGCGGTNNNNNNNNNAGCGGCNCCCACCNNNNNNNNGGAGAAGCCTCCAGCC
GAGGCCCAGGACGAACCTGCAGAGTCGCTGAGCGAGTTCAAGCCCTTCTTTGGGAATATA
ATTATCACCGACGTCACCGCGAACTGCCTCACCGTTACTTTCAAGGAGTACGTGACGGTG
TAG

Clone variation with respect to NM_003655.2
1515 g=>n;1516 g=>n;1517 c=>n;1518 g=>n;1519 g=>n;1520 c=>n;1521 g=>n;1522 g=>n;1523 c=>n;1530 a=>n;1537 a=>n;1538 c=>n;1539 g=>n;1540 a=>n;1541 c=>n;1542 g=>n;1543 g=>n;1544 c=>n
>OriGene 5' read for NM_003655 unedited
TACTATAGGGCGGCCGCGAATTCGGCACGAGGGCGAGCCGGGAGCCGGGGCGGGCGCGGG
CAGCGGCGGGCCGGCCGGGCTGTGCGGGGCGAGCGGCGGCGGCGGCGGGGGCGCTTCGGC
CGGGGCGGCAGCTGGGCGCCGGCGGGAGCTAGCAGCGTCTGCAGCCGCGCCGGCCGCCAG
CGCCCCGGCGCGCTCCGGCTCGGCCATGGAGCTGCCAGCTGTTGGCGAGCACGTCTTCGC
GGTGGAGAGCATCGAGAAGAAGCGGATCCGCAAGGGCAGAGTGGAGTATCTGGTGAAATG
GAGAGGCTGGTCGCCCAAATATAACACGTGGGAACCGGAGGAGAACATCCTGGACCCCAG
GCTGCTGATCGCCTTCCAGAACAGGGAACGGCAGGAGCAGCTGATGGGATATCGGAAGAG
AGGGCCGAAGCCCAAACCGCTAGTGGTGCAGGTGCCTACCTTTGCCCGTCGTTCCAATGT
CCTGACCGGCCTCCAGGACTCCTCCACTGACAACCGTGCCAAGCTGGGATTGGGCGCGCA
GGGGGAAGGGCCAGGGGCATCAGTACGAGCTCACAGCAGAAACACCCCAGTACAGCCGCA
CAGAGGAGCGGGCGGCAAGCCCCGCGCCGGCAGAGCGGCAGTCTACTACAGCTCACAGCA
GAGCACACCCCTACAGCCGACCCAAATGACGACTGCAGACCAGGCGGCCACAGAGGGCCA
GCCCACTGCCGGACTTGGGGCCAAGACCACCGCCGACAGAGGCGCAGGGGGGGGGCCAAG
GCTCTGGGGGCGGAAAACCCCGGCGGGGGGGGGGGCTCAGAAGGCTCCAAAAGCCCCCCC
GGAAGACCCGGCCCAAAAGGTTGACGCCACGAATGGGGCAAATAAATCTCCAAAAACAAA
CAGCCTCTTTCCTAAACCAATCAGAACGCTTCGCGGGGTAACCCCGG
>OriGene 3' read for NM_003655 unedited
CCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTCAACATCTCCATTTAATATTT
ACATTCAAGCAGGTAATAGTTGGAAGCTTATAGTTTAGACATTTCTAGTAGCAGCAGTTT
CTAGAGAGCTCGTGTAGCCTTTTAACAAACTTTTTTTTTTTTTTTTTTTGCACATAAAAA
CAAGACATCCATGTGTACAGTATCAAAAAATATATACCAAGGTTACTGGTATTGCAGTTC
GGGGAAGGGGAAAAAAGGGGAAAAAATGAAATCAACCGAAATACTGGATGGAGGGGAAAA
AAGGTCAAAAAAAAATAGTTGGTCTGATATAGAATATAACATGATCTAGAGGAAACTCCA
TAAATCTAGGTTTTTATATTTCAATATATAAATCCCTACAAATAAATATATATATAGCAG
CCCGAAGGGGGGGGGTCGGGCCTTTTGAGCTCAAACAATACATTTCAATAATAACACCAC
GTACAAACGGGAGTAGAGTCAGCACTTGACAAGTTAGCACGGTTAAAATATAATACTAGA
ACTCTGAGGCCGGGCGCAGAGCTGCCCTGTCCGTTCCGGGGTCCATCTCCACCGGGGAAG
GGCAGGAAAGGGCGACCCCCGCCGGCACCGCGTGGAAGGGGCCTCCCCCCAGGTCTGACA
GCCGCCGCAGGGGGAACATGGTTACCTCCGCTCCGGGCGTCCTCACCCTGGGGGCCAGCC
TGGGTCTCTCCCGGTTTGGCGGTTTGCAAAGAGGGGACCCCCCCCGAGGGCCCAGGGGCT
ATCTCCCCGCCCCCCTGCGGGAATGGGCGTTTCCCTTCCAAGCCCCTCCGGGTTACACCG
GACGTACTCCTTGAAAGCACAGGGGAAGGCCTCCTGGGCGCCCTGCGTGCAAACTTTTTT
CCAAAAGAGGCTTGACACTCCCACCGCCTTGGGGGTCCTCCTGGCCCTGGCGGAGCTTCC
CCCGCCGGCGNCGGGGCCTATCCCCCCCTCCCACTCCCGT
Restriction Sites NotI-NotI     
ACCN NM_003655
Insert Size 2740 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_003655.2, NP_003646.2
RefSeq Size 2655 bp
RefSeq ORF 1683 bp
Locus ID 8535
UniProt ID O00257
Domains CHROMO
Protein Families Druggable Genome, Transcription Factors
Gene Summary E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I (PubMed:12679040). Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131 (PubMed:22825850).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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