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IKAP (IKBKAP) (NM_003640) Human Untagged Clone
CAT＃: SC117829
IKBKAP (untagged)-Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP)
CNY 13,920.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DYS; FD; IKAP; IKBKAP; IKI3; TOT1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003640 edited
ATGCGAAATCTGAAATTATTTCGGACCCTGGAGTTCAGGGATATTCAAGGTCCAGGGAAT CCTCAGTGCTTCTCTCTCCGAACTGAACAGGGGACGGTGCTCATTGGTTCAGAACATGGC CTGATAGAAGTAGACCCTGTCTCAAGAGAAGTGAAAAATGAAGTTTCTTTGGTGGCAGAA GGCTTTCTCCCAGAGGATGGAAGTGGCCGCATTGTTGGTGTTCAGGACTTGCTGGATCAG GAGTCTGTGTGTGTGGCCACAGCCTCTGGAGACGTCATACTCTGCAGTCTCAGCACACAA CAGCTGGAGTGTGTTGGGAGTGTAGCCAGTGGTATCTCTGTTATGAGTTGGAGTCCTGAC CAAGAGCTGGTGCTTCTTGCCACAGGTCAACAGACCCTGATTATGATGACAAAAGATTTT GAGCCAATCCTGGAGCAGCAGATCCATCAGGATGATTTTGGTGAAAGCAAGTTTATCACT GTTGGATGGGGTAGGAAGGAGACACAGTTCCATGGATCAGAAGGCAGACAAGCAGCTTTT CAGATGCAAATGCATGAGTCTGCTTTGCCCTGGGATGACCATAGACCACAAGTTACCTGG CGGGGGGATGGACAGTTTTTTGCTGTGAGTGTTGTTTGCCCAGAAACAGGGGCTCGGAAG GTCAGAGTGTGGAACCGAGAGTTTGCTTTGCAGTCAACCAGTGAGCCTGTGGCAGGACTG GGACCAGCCCTGGCTTGGAAACCCTCAGGCAGTTTGATTGCATCTACACAAGATAAACCC AACCAGCAGGATATTGTGTTTTTTGAGAAAAATGGACTCCTTCATGGACACTTTACACTT CCCTTCCTTAAAGATGAGGTTAAGGTAAATGACTTGCTCTGGAATGCAGATTCCTCTGTG CTTGCAGTCTGGCTGGAAGACCTTCAGAGAGAAGAAAGCTCCATTCCGAAAACCTGTGTT CAGCTCTGGACTGTTGGAAACTATCACTGGTATCTCAAGCAAAGTTTATCCTTCAGCACC TGTGGGAAGAGCAAGATTGTGTCTCTGATGTGGGACCCTGTGACCCCATACCGGCTGCAT GTTCTCTGTCAGGGCTGGCATTACCTCGCCTATGATTGGCACTGGACGACTGACCGGAGC GTGGGAGATAATTCAAGTGACTTGTCCAATGTGGCTGTCATTGATGGAAACAGGGTGTTG GTGACAGTCTTCCGGCAGACTGTGGTTCCGCCTCCCATGTGCACCTACCAACTGCTGTTC CCACACCCTGTGAATCAAGTCACATTCTTAGCACACCCTCAAAAGAGTAATGACCTTGCT GTTCTAGATGCCAGTAACCAGATTTCTGTTTATAAATGTGGTGATTGTCCAAGTGCTGAC CCTACAGTGAAACTGGGAGCTGTGGGTGGAAGTGGATTTAAAGTTTGCCTTAGAACTCCT CATTTGGAAAAGAGATACAAAATCCAGTTTGAGAATAATGAAGATCAAGATGTAAACCCG CTGAAACTAGGCCTTCTCACTTGGATTGAAGAAGACGTCTTCCTGGCTGTAAGCCACAGT GAGTTCAGCCCCCGGTCTGTCATTCACCATTTGACTGCAGCTTCTTCTGAGATGGATGAA GAGCATGGACAGCTCAATGTCAGTTCATCTGCAGCGGTGGATGGGGTCATAATCAGTCTA TGTTGCAATTCCAAGACCAAGTCAGTAGTATTACAGCTGGCTGATGGCCAGATATTTAAG TACCTTTGGGAGTCACCTTCTCTGGCTATTAAACCATGGAAGAACTCTGGTGGATTTCCT GTTCGGTTTCCTTATCCATGCACCCAGACCGAATTGGCCATGATTGGAGAAGAGGAATGT GTCCTTGGTCTGACTGACAGGTGTCGCTTTTTCATCAATGACATTGAGGTTGCGTCAAAT ATCACGTCATTTGCAGTATATGATGAGTTTTTATTGTTGACAACCCATTCCCATACCTGC CAGTGTTTTTGCCTGAGGGATGCTTCATTTAAAACATTACAGGCCGGCCTGAGCAGCAAT CATGTGTCCCATGGGGAAGTTCTGCGGAAAGTGGAGAGGGGTTCACGGATTGTCACTGTT GTGCCCCAGGACACAAAGCTTGTATTACAGATGCCAAGGGGAAACTTAGAAGTTGTTCAT CATCGAGCCCTGGTTTTAGCTCAGATTCGGAAGTGGTTGGACAAACTTATGTTTAAAGAG GCATTTGAATGCATGAGAAAGCTGAGAATCAATCTCAATCTGATTTATGATCATAACCCT AAGGTGTTTCTTGGAAATGTGGAAACCTTCATTAAACAGATAGATTCTGTGAATCATATT AACTTGTTTTTTACAGAATTGAAAGAAGAAGATGTCACGAAGACCATGTACCCTGCACCA GTTACCAGCAGTGTCTACCTGTCCAGGGATCCTGACGGGAATAAAATAGACCTTGTCTGC GATGCTATGAGAGCAGTCATGGAGAGCATAAATCCTCATAAATACTGCCTATCCATACTT ACATCTCATGTAAAGAAGACAACCCCAGAACTGGAAATTGTACTGCAAAAAGTACACGAG CTTCAAGGAAATGCTCCCTCTGATCCTGATGCTGTGAGTGCTGAAGAGGCCTTGAAATAT TTGCTGCATCTGGTAGATGTTAATGAATTATATGATCATTCTCTTGGCACCTATGACTTT GATTTGGTCCTCATGGTAGCTGAGAAGTCACAGAAGGATCCCAAAGAATATCTTCCATTT CTTAATACACTTAAGAAAATGGAAACTAATTATCAGCGGTTTACTATAGACAAATACTTG AAACGATATGAAAAAGCCATTGGCCACCTCAGCAAATGTGGACCTGAGTACTTCCCAGAA TGCTTAAACTTGATAAAAGATAAAAACTTGTATAACGAAGCTCTGAAGTTATATTCACCA AGCTCACAACAGTACCAGGATATCAGCATTGCTTATGGGGAGCACCTGATGCAGGAGCAC ATGTATGAGCCAGCGGGGCTCATGTTTGCCCGTTGCGGTGCCCACGAGAAAGCTCTCTCA GCCTTTCTCACATGTGGCAACTGGAAGCAAGCCCTCTGTGTGGCAGCCCAGCTTAACTTT ACCAAAGACCAGCTGGTGGGCCTCGGCAGAACTCTGGCAGGAAAGCTGGTTGAGCAGAGG AAGCACATTGATGCGGCCATGGTTTTGGAAGAGTGTGCCCAGGATTATGAAGAAGCTGTG CTCTTGCTGTTAGAAGGAGCTGCCTGGGAAGAAGCTTTGAGGCTGGTATACAAATATAAC AGACTGGATATTATAGAAACCAACGTAAAGCCTTCCATTTTAGAAGCCCAGAAAAATTAT ATGGCATTTCTGGACTCTCAGACAGCCACATTCAGTCGCCACAAGAAACGTTTATTGGTA GTTCGAGAGCTCAAGGAGCAAGCCCAGCAGGCAGGTCTGGATGATGAGGTACCCCACGGG CAAGAGTCAGACCTCTTCTCTGAAACTAGCAGTGTCGTGAGTGGCAGTGAGATGAGTGGC AAATACTCCCATAGTAACTCCAGGATATCAGCGAGATCATCCAAGAATCGCCGAAAAGCG GAGCGGAAGAAGCACAGCCTCAAAGAAGGCAGTCCGCTGGAGGACCTGGCCCTCCTGGAG GCACTGAGTGAAGTGGTGCAGAACACTGAAAACCTGAAAGATGAAGTATACCATATTTTA AAGGTACTCTTTCTCTTTGAGTTTGATGAACAAGGAAGGGAATTACAGAAGGCCTTTGAA GATACGCTGCAGTTGATGGAAAGGTCACTTCCAGAAATTTGGACTCTTACTTACCAGCAG AATTCAGCTACCCCGGTTCTAGGTCCCAATTCTACTGCAAATAGTATCATGGCATCTTAT CAGCAACAGAAGACTTCGGTTCCTGTTCTTGATGCTGAGCTTTTTATACCACCAAAGATC AACAGAAGAACCCAGTGGAAGCTGAGCCTGCTAGAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003640 |
| Insert Size | 4400 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_003640.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003640.2, NP_003631.2 |
| RefSeq Size | 5917 bp |
| RefSeq ORF | 3999 bp |
| Locus ID | 8518 |
| UniProt ID | O95163 |
| Domains | IKI3 |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207686 | IKBKAP (Myc-DDK-tagged)-Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP) |
CNY 13,912.00 |
|
| RC207686L1 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP), Myc-DDK-tagged |
CNY 16,312.00 |
|
| RC207686L2 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP), mGFP tagged |
CNY 15,200.00 |
|
| RC207686L3 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP), Myc-DDK-tagged |
CNY 15,200.00 |
|
| RC207686L4 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP), mGFP tagged |
CNY 15,200.00 |
|
| RG207686 | IKBKAP (tGFP-tagged) - Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein (IKBKAP) |
CNY 15,512.00 |
