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NMDAR1 (GRIN1) (NM_007327) Human Untagged Clone
CAT＃: SC115601
GRIN1 (untagged)-Human glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-3
CNY 6,880.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GluN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>SC115601 representing NM_007327.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCGGCCGCGAATTCGGCACGAGGACGGCCCGGAAGCCCCGCGGGGGATGCGCCGAGGGCCCCGCGTTCG CGCCGCGCAGAGCCAGGCCCGCGGCCCGAGCCCATGAGCACCATGCGCCTGCTGACGCTCGCCCTGCTG TTCTCCTGCTCCGTCGCCCGTGCCGCGTGCGACCCCAAGATCGTCAACATTGGCGCGGTGCTGAGCACG CGGAAGCACGAGCAGATGTTCCGCGAGGCCGTGAACCAGGCCAACAAGCGGCACGGCTCCTGGAAGATT CAGCTCAATGCCACCTCCGTCACGCACAAGCCCAACGCCATCCAGATGGCTCTGTCGGTGTGCGAGGAC CTCATCTCCAGCCAGGTCTACGCCATCCTAGTTAGCCATCCACCTACCCCCAACGACCACTTCACTCCC ACCCCTGTCTCCTACACAGCCGGCTTCTACCGCATACCCGTGCTGGGGCTGACCACCCGCATGTCCATC TACTCGGACAAGAGCATCCACCTGAGCTTCCTGCGCACCGTGCCGCCCTACTCCCACCAGTCCAGCGTG TGGTTTGAGATGATGCGTGTCTACAGCTGGAACCACATCATCCTGCTGGTCAGCGACGACCACGAGGGC CGGGCGGCTCAGAAACGCCTGGAGACGCTGCTGGAGGAGCGTGAGTCCAAGGCAGAGAAGGTGCTGCAG TTTGACCCAGGGACCAAGAACGTGACGGCCCTGCTGATGGAGGCGAAAGAGCTGGAGGCCCGGGTCATC ATCCTTTCTGCCAGCGAGGACGATGCTGCCACTGTATACCGCGCAGCCGCGATGCTGAACATGACGGGC TCCGGGTACGTGTGGCTGGTCGGCGAGCGCGAGATCTCGGGGAACGCCCTGCGCTACGCCCCAGACGGC ATCCTCGGGCTGCAGCTCATCAACGGCAAGAACGAGTCGGCCCACATCAGCGACGCCGTGGGCGTGGTG GCCCAGGCCGTGCACGAGCTCCTCGAGAAGGAGAACATCACCGACCCGCCGCGGGGCTGCGTGGGCAAC ACCAACATCTGGAAGACCGGGCCGCTCTTCAAGAGAGTGCTGATGTCTTCCAAGTATGCGGATGGGGTG ACTGGTCGCGTGGAGTTCAATGAGGATGGGGACCGGAAGTTCGCCAACTACAGCATCATGAACCTGCAG AACCGCAAGCTGGTGCAAGTGGGCATCTACAATGGCACCCACGTCATCCCTAATGACAGGAAGATCATC TGGCCAGGCGGAGAGACAGAGAAGCCTCGAGGGTACCAGATGTCCACCAGACTGAAGATTGTGACGATC CACCAGGAGCCCTTCGTGTACGTCAAGCCCACGCTGAGTGATGGGACATGCAAGGAGGAGTTCACAGTC AACGGCGACCCAGTCAAGAAGGTGATCTGCACCGGGCCCAACGACACGTCGCCGGGCAGCCCCCGCCAC ACGGTGCCTCAGTGTTGCTACGGCTTTTGCATCGACCTGCTCATCAAGCTGGCACGGACCATGAACTTC ACCTACGAGGTGCACCTGGTGGCAGATGGCAAGTTCGGCACACAGGAGCGGGTGAACAACAGCAACAAG AAGGAGTGGAATGGGATGATGGGCGAGCTGCTCAGCGGGCAGGCAGACATGATCGTGGCGCCGCTAACC ATAAACAACGAGCGCGCGCAGTACATCGAGTTTTCCAAGCCCTTCAAGTACCAGGGCCTGACTATTCTG GTCAAGAAGGAGATTCCCCGGAGCACGCTGGACTCGTTCATGCAGCCGTTCCAGAGCACACTGTGGCTG CTGGTGGGGCTGTCGGTGCACGTGGTGGCCGTGATGCTGTACCTGCTGGACCGCTTCAGCCCCTTCGGC CGGTTCAAGGTGAACAGCGAGGAGGAGGAGGAGGACGCACTGACCCTGTCCTCGGCCATGTGGTTCTCC TGGGGCGTCCTGCTCAACTCCGGCATCGGGGAAGGCGCCCCCAGAAGCTTCTCAGCGCGCATCCTGGGC ATGGTGTGGGCCGGCTTTGCCATGATCATCGTGGCCTCCTACACCGCCAACCTGGCGGCCTTCCTGGTG CTGGACCGGCCGGAGGAGCGCATCACGGGCATCAACGACCCTCGGCTGAGGAACCCCTCGGACAAGTTT ATCTACGCCACGGTGAAGCAGAGCTCCGTGGATATCTACTTCCGGCGCCAGGTGGAGCTGAGCACCATG TACCGGCATATGGAGAAGCACAACTACGAGAGTGCGGCGGAGGCCATCCAGGCCGTGAGAGACAACAAG CTGCATGCCTTCATCTGGGACTCGGCGGTGCTGGAGTTCGAGGCCTCGCAGAAGTGCGACCTGGTGACG ACTGGAGAGCTGTTTTTCCGCTCGGGCTTCGGCATAGGCATGCGCAAAGACAGCCCCTGGAAGCAGAAC GTCTCCCTGTCCATCCTCAAGTCCCACGAGAATGGCTTCATGGAAGACCTGGACAAGACGTGGGTTCGG TATCAGGAATGTGACTCGCGCAGCAACGCCCCTGCGACCCTTACTTTTGAGAACATGGCCGGGGTCTTC ATGCTGGTAGCTGGGGGCATCGTGGCCGGGATCTTCCTGATTTTCATCGAGATTGCCTACAAGCGGCAC AAGGATGCTCGCCGGAAGCAGATGCAGCTGGCCTTTGCCGCCGTTAACGTGTGGCGGAAGAACCTGCAG GATAGAAAGAGTGGTAGAGCAGAGCCTGACCCTAAAAAGAAAGCCACATTTAGGGCTATCACCTCCACC CTGGCTTCCAGCTTCAAGAGGCGTAGGTCCTCCAAAGACACGAGCACCGGGGGTGGACGCGGCGCTTTG CAAAACCAAAAAGACACAGTGCTGCCGCGACGCGCTATTGAGAGGGAGGAGGGCCAGCTGCAGCTGTGT TCCCGTCATAGGGAGAGCTGAGACTCCCCGCCCGCCCTCCTCTGCCCCCTCCCCCGCAGACAGACAGAC AGACGGACGGGACAGCGGCCCGGCCCACGCAGAGCCCCGGAGCACCACGGGGTCGGGGGAGGAGCACCC CCAGCCTCCCCCAGGCTGCGCCTGCCCGCCCGCCGGTTGGCCGGCTGGCCGGTCCACCCCGTCCCGGCC CCGCGCGTGCCCCCAGCGTGGGGCTAACGGGCGCCTTGTCTGTGTATTTCTATTTTGCAGCAGTACCAT CCCACTGATATCACGGGCCCGCTCAACCTCTCAGATCCCTCGGTCAGCACCGTGGTGTGAGGCCCCCGG AGGCGCCCACCTGCCCAGTTAGCCCGGCCAAGGACACTGATGGGTCCTGCTGCTCGGGAAGGCCTGAGG GAAGCCCACCCGCCCCAGAGACTGCCCACCCTGGGCCTCCCGTCCGTCCGCCCGCCCACCCCGCTGCCT GGCGGGCAGCCCCTGCTGGACCAAGGTGCGGACCGGAGCGGCTGAGGACGGGGCAGAGCTGAGTCGGCT GGGCAGGGCCGCAGGGCGCTCCGGCAGAGGCAGGGCCCTGGGGTCTCTGAGCAGTGGGGAGCGGGGGCT AACTGGCCCCAGGCGGAGGGGCTTGGAGCAGAGACGGCAGCCCCATCCTTCCCGCAGCACCAGCCTGAG CCACAGTGGGGCCCATGGCCCCAGCTGGCTGGGTCGCCCCTCCTCGGGCGCCTGCGCTCCTCTGCAGCC TGAGCTCCACCCTCCCCTCTTCTTGCGGCACCGCCCACCCACACCCCGTCTGCCCCTTGACCCCACACG CCGGGGCTGGCCCTGCCCTCCCCCACGGCCGTCCCTGACTTCCCAGCTGGCAGCGCCTCCCGCCGCCTC GGGCCGCCTCCTCCAGACTCGAGAGGGCTGAGCCCCTCCTCTCCTCGTCCGGCCTGCAGCCCAGAACGG GCCTCCCCGGGGGTCCCCGGACGCTGGCTCGGGACTGTCTTCAACCCTGCCCTGCACCTTGGGCACGGG AGAGCGCCACCCGCCCGCCCCCGCCCTCGCTCCGGGTGCGTGACCGGCCCGCCACCTTGTACAGAACCA GCACTCCCAGGGCCCGAGCGCGTGCCTTCCCCGTGCGGCCCGTGCGCAGCCGCGCTCTGCCCCTCCGTC CCCAGGGTGCAGGCGCGCACCGCCCAACCCCCACCTCCCGGTGTATGCAGTGGTGATGCCTAAAGGAAT GTCACGCAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGC >OriGene 5' read for NM_007327 unedited
AAAAGGTACCGGCGCCCGTTCCCTTAAAGGGCGGTAGGCGTGCACGGTGGGAGGTCTATA TAAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGG CCGCGAATTCGGCACGAGGACGGCCCGGAAGCCCCGCGGGGGATGCGCCGAGGGCCCCGC GTTCGCGCCGCGCAGAGCCAGGCCCGCGGCCTGATCCCATGAGCACCATGCGCCTGCTGA CGCTCGCCCTGCTGTTCTCCTGCTCCGTCGCCCGTGCCGCGTGCGACCCCAAGATCGTCA ACATTGGCGCGGTGCTGAGCACGCGGAAGCACGAGCAGATGTTCCGCGAGGCCGTGAACC AGGCCAACAAGCGGCACGGCTCCTGGAAGATTCAGCTCAATGCCACCTCCGTCACGCACA AGCCCAACGCCATCCAGATGGCTCTGTCGGTGTGCGAGGACCTCATCTCCAGCCAGGTCT ACGCCATCCTAGTTAGCCATCCACCTACCCCCAACGACCACTTCACTCCCACCCCTGTCT CCTACACAGCCGGCTTCTACCGCATACCCGTGCTGGGGCTGACCACCCGCATGTCCATCT ACTCGGACAAGAGCATCCACCTGAGCTTCCTGCGCACCGTGCCGCCCTACTCCCACCAGT CCAGCGTGTGGTTTGAGATGATGCGTGTCTACAGCTGGAACCACATCATCCTGCTGGTCA GCGACGACCACGAGGGCCGGGCGGCTCAGAAACGCCTGGAGACGCTGCTGGAGGAGCGTG AGTCCCAAGCAGAGAAAGTGCTGCAGTTTGACCCAGGGACCAAAACGTGNACGCCCTGCT GATGGAGCGAAAGAGCTGGNAGCCGGGTCATCATCCTTTCTGCCAGCGAGGCGATGCTGC CN >OriGene 3' read for NM_007327 unedited
NCTACTATGTACCGTGGCCGCGCTCNAAGATCGGTTTTTTTTTTTTTTTTTTGCGTGACA TTCCTTTAGGCATCACCACTGCATACACCGGGAGGTGGGGGTTGGGCGGTGCGCGCCTGC ACCCTGGGGACGGAGGGGCAGAGCGCGGCTGCGCACGGGCCGCACGGGGAAGGCACGCGC TCGGGCCCTGGGAGTGCTGGTTCTGTACAAGGTGGCGGGCCGGTCACGCACCCGGATCGA GGGCGGGGGCGGGCGGGTGGCGCTCTCCCGTGCCCAAGGTGCAGGGCAGGGTTGAAGACA GTCCCGAGCCAGCGTCCGGGGACCCCCGGGGAGGCCCGTTCTGGGCTGCAGGCCGGACGA GGAGAGGAGGGGCTCAGCCCTCTCGAGTCTGGAGGATGCGGCCCGAGGCGGCGGGAGGCG CTGCCAGCTGGGAAGTCAGGGACGGCCGTGGGGGATGGCAGGGCCAGCCCCGGCGTGTGG GGTCAAGGGGCATACGGGGTGTGGGTGGGCGGTGCCGCAAGAAGAGGGGAGGGTGGAGCT CAAGCTGCAGAGGAGCGCATGCGCCCGATGAGGGGCGACCCAGCCAGCTGGTGCCATGGG CCCCCACTGTGGCTCATGCTGGTGCTGCGGGAATGATGGGGGCTGCCGTCTCTGCTTCCA GCCCCTTCGGCTGGGGCCAGTTAGCCCCCGCTCCCCACTGCTTATAGACCATAAGGCCCT GCCTCTGGCGGGAGCGCCCTGGGGCCTTGGCCCAGCCGACTCAACTTTGGCCCGTTCTTA ACCGTTTCGGGTCGGACCTTGGTTCCACAAGGGCTGCCCGCCCGGCATCGGGTGGGCCGG GCCGGCGGACGGGAGGCCCAGGTGGGCAGTCTTCTGGGGCGGTGGGGCTTCCCCAGGCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007327 |
| Insert Size | 4187 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007327.1 |
| RefSeq Size | 5137 bp |
| RefSeq ORF | 4187 bp |
| Locus ID | 2902 |
| UniProt ID | Q05586 |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Huntington's disease, Long-term potentiation, Neuroactive ligand-receptor interaction |
| MW | 152.9 kDa |
| Gene Summary | The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (GluN1-1a, also known as NR1-3) represents the longest transcript and encodes protein isoform GluN1-1a (also known as isoform NR1-3). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit
,null,
PLoS ONE
,PubMed ID 26829109
[GRIN1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216458 | GRIN1 (Myc-DDK-tagged)-Human glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-3 |
CNY 10,304.00 |
|
| RC216458L1 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-3, Myc-DDK-tagged |
CNY 12,704.00 |
|
| RC216458L2 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-3, mGFP tagged |
CNY 11,690.00 |
|
| RC216458L3 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-3, Myc-DDK-tagged |
CNY 12,704.00 |
|
| RC216458L4 | Lenti ORF clone of Human glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-3, mGFP tagged |
CNY 12,704.00 |
|
| RG216458 | GRIN1 (tGFP-tagged) - Human glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-3 |
CNY 11,904.00 |
