NUDT15 (NM_018283) Human Untagged Clone

CAT#: SC113594

NUDT15 (untagged)-Human nudix (nucleoside diphosphate linked moiety X)-type motif 15 (NUDT15)



  "NM_018283" in other vectors (6)

CNY 1,800.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
NUDT15 mouse monoclonal antibody,clone OTI4B9
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms MTH2; NUDT15D
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC113594 sequence for NM_018283 edited (data generated by NextGen Sequencing)
ATGACGGCCAGCGCACAGCCGCGCGGGCGGCGGCCAGGAGTCGGAGTCGGAGTCGTGGTG
ACCAGCTGCAAGCATCCGCGTTGCGTCCTCCTGGGGAAGAGGAAAGGCTCGGTTGGAGCT
GGCAGTTTCCAACTCCCTGGAGGTCATCTGGAGTTCGGTGAAACCTGGGAAGAATGTGCT
CAAAGGGAAACCTGGGAAGAAGCAGCTCTTCACCTGAAAAATGTTCACTTTGCCTCAGTT
GTGAATTCTTTCATTGAGAAGGAGAATTACCATTATGTTACTATATTAATGAAAGGAGAA
GTGGATGTGACTCATGATTCAGAACCAAAGAATGTAGAGCCTGAAAAAAATGAAAGTTGG
GAGTGGGTTCCTTGGGAAGAACTACCTCCCCTGGACCAGCTTTTCTGGGGACTGCGTTGT
TTAAAAGAACAAGGCTATGATCCATTTAAAGAAGATCTGAACCATCTGGTGGGATACAAA
GGAAATCATCTCTAG

Clone variation with respect to NM_018283.1
>OriGene 5' read for NM_018283 unedited
TGTCACATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGCCCGCGCGCT
ATGACGGCCAGCGCACAGCCGCGCGGGCGGCGGCCAGGAGTCGGAGTCGGAGTCGTGGTG
ACCAGCTGCAAGCATCCGCGTTGCGTCCTCCTGGGGAAGAGGAAAGGCTCGGTTGGAGCT
GGCAGTTTCCAACTCCCTGGAGATCATCTGGAGTTCGGTGAAACCTGGGAAGAATGTGCT
CAAAGGGAAACCTGGGAAGAAGCAGCTCTTCACCTGAAAAATGTTCACTTTGCCTCAGTT
GTGAATTCTTTCATTGAGAAGGAGAATTACCATTATGTTACTATATTAATGAAAGGAGAA
GTGGATGTGACTCATGATTCAGAACCAAAGAATGTAGAGCCTGAAAAAAATGAAAGTTGG
GAGTGGGTTCCTTGGGAAGAACTACCTCCCCTGGACCAGCTTTTCTGGGGACTGCGTTGT
TTAAAAGAACAAGGCTATGATCCATTTAAAGAAGATCTGAACCATCTGGTGGGATACAAA
GGAAATCATCTCTAGGTGGCCAAGAAGATTTGATTTTCTTTAAAAAGACAAGAATAAGGT
CTGGTTAGGGAATGAAAAATGTATACATTTCGGAACAACTCCATTTTATCTAAAAAAGTT
CTTGTGATTGCCAGTTTATTTGCAGTCTCTTATGTATCCCCCCTCTTTCAGCCAGTACTT
GAGAAAATTTTTCTGAATATGTCATTGAATTGTATTCCAGACACAGAATACATGATAAAT
ACTGATATTATGGGTAATCTGCTTCCATATTTACTATGATATTACTGTGCAGNTTGNATT
ACTAGCTGCATGGAGTAGATGCATCAAATTGCCTTAGTGTTTCTGTCAATAGAGACCCTG
ATCAATTT
>OriGene 3' read for NM_018283 unedited
GCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TAATTTCTTAAAATTTTTATTAATCATTTGCAAGTAACAAGAACCAAGTTTATATAAACA
CATAAAAACATTTTTGGCAAATAGCTAATTTTATTTTTTTCACATATTAAAACCCACTAA
AAATAACCATTTTTCTAACTAACCACAACAAAAATTAGGGAGAAAAGTACTGGTGCTTTA
CATTTCTCCAAATCTCTTCAATGTCTGATGACAGACGAAAGCTGGAATCTTGGATCTGCT
TTTGCATTCAGCCTATTACAATATCACACCAGATAGCCTCTTGAAAACTCCTCTGCATAC
TCATGAAAAAATGAGGGAAAAAGATAAATGATGGCTGGGCGTTGGGGCTCATACCTGTAA
TCCCAGCACTTTGGGAGGCTGAAATGGGCAAATCACTTGAGCTCAGGAGTTCCAGACCAG
CCTGGCCAACATGGGGAAACCCCGTCTCCACTAAAAATACAAAAATTAGCCAGGTGTGGG
GGTGGGTGCCTATAATCCCAGCTACTCGGGAAGCTGAGGTAGGAGAATTGCTTGAACCCA
GGTGGCGGAGGCTGCAATGAGCTGAGATCGCGCCACTGCACTCCAATGTGGGCACCAGAG
CAAGACTCCTTCTAAAATAAAAAAAGGGAAAGCTATAAATAGCGAAATGATGTCTTAGTG
TTATAAAAACAGTTTTGACCCAAAAAACCCTTGAAGGCTTTTGAGGCCCCCCCAGACCAA
ATTTTGACACCCACTGTTCTAGACGAATCTCTTCATATAAAGAAACCTTTCATAATAAGA
ACCCCTGGCCTCAAAAAGAAGTAGTGGGAAACTCACCTCCAAGCCTTTAAAAGCCTGAAC
AGAATATAAAGGGTTGCCCAACTCTTTTGGTTTAAATCCTACATGG
Restriction Sites NotI-NotI     
ACCN NM_018283
Insert Size 2000 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_018283.1, NP_060753.1
RefSeq Size 2022 bp
RefSeq ORF 495 bp
Locus ID 55270
UniProt ID Q9NV35
Domains NUDIX
Gene Summary This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Apr 2016]
Transcript Variant: This variant (1) encodes the longer isoform (1).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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