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NUDT15 (NM_018283) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC210477L3V
- LentiORF®
-
Lenti ORF particles, NUDT15 (Myc-DDK tagged) - Human nudix (nucleoside diphosphate linked moiety X)-type motif 15 (NUDT15), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | NUDT15 (NM_018283) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | MTH2; NUDT15D |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_018283 |
| ORF Size | 492 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC210477).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_018283.1 |
| RefSeq Size | 2022 bp |
| RefSeq ORF | 495 bp |
| Locus ID | 55270 |
| Domains | NUDIX |
| MW | 18.4 kDa |
| Gene Summary | This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Apr 2016] |
Documents
| Product Manuals |
| FAQs |
| SDS |
