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Cyclophilin A (PPIA) (NM_021130) Human Untagged Clone
CAT＃: SC111937
PPIA (untagged)-Human peptidylprolyl isomerase A (cyclophilin A) (PPIA)
CNY 1,800.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CYPA; CYPH; HEL-S-69p |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111937 sequence for NM_021130 edited (data generated by NextGen Sequencing)
ATGGTCAACCCCACCGTGTTCTTCGACATTGCCGTCGACGGCGAGCCCTTGGGCCGCGTC TCCTTTGAGCTGTTTGCAGACAAGGTCCCAAAGACAGCAGAAAATTTTCGTGCTCTGAGC ACTGGAGAGAAAGGATTTGGTTATAAGGGTTCCTGCTTTCACAGAATTATTCCAGGGTTT ATGTGTCAGGGTGGTGACTTCACACGCCATAATGGCACTGGTGGCAAGTCCATCTATGGG GAGAAATTTGAAGATGAGAACTTCATCCTAAAGCATACGGGTCCTGGCATCTTGTCCATG GCAAATGCTGGACCCAACACAAATGGTTCCCAGTTTTTCATCTGCACTGCCAAGACTGAG TGGTTGGATGGCAAGCATGTGGTGTTTGGCAAAGTGAAAGAAGGCATGAATATTGTGGAG GCCATGGAGCGCTTTGGGTCCAGGAATGGCAAGACCAGCAAGAAGATCACCATTGCTGAC TGTGGACAACTCGAATAA Clone variation with respect to NM_021130.3 >OriGene 5' read for NM_021130 unedited
CGACTCACATAGGCGGCCGCGAAATTCGCACGAGGTGCCACCGCCGAGGAAAAACCGTGT ACTCTTAGCCATGGTCAACCCCACCGTGTTCTTCGACATTGCCGTCGACGGCGAAGCCCT TGGGCCGCGTCTCCTTTGAGCTGTTTGCAGACAAGGTCCCAAAGACAGCAGAAAAATTTT CGTGCTCTGAGCACTGGAGAGAAAGGATTTGGTTATAAGGGTTCCTGCTTTCACAGAATT ATTCCAGGGTTTATGTGTCAGGGTGGTGACTTCACACGCCATAATGGCACTGGTGGCAAG TCCATCTATGGGGAGAAATTTGAAGATGAGAACTTCATCCTAANAGCATACGGGTCCTGG CATCTTGTCCATGGCAAATGCTGGACCCAACACAAATGGTTCCCAGTTTTTCATCTGCAC TGCCAAGACTGAGTGGTTGGATGGCAAGCATGTGGGTGTTTGGCAAAGTGAAAGAAGCAT GAATATTGTTGGAGGCCATGGAGCGCTTTTGGGTCCAGGAATGGCAAGACCAGCAAGAAG ATCACCATTGNCTGACTGTGGACACTGGAATAAGTTTGACTTTGGTGTTTTATCTTAACC ACCAGATCATTCCTTCTGTAGCTCAGGAGAGCACCCCTCCACCCCATTTGCTTCGCAGTA TCCTAGAATACTTTGTGCTCTCGCCTGCAGTCCCCTCTTTGGGTTTCCAATGGTTTTCCT TTGGTCCCTTCCATGCCTAGNCTTGATTGCAAAGGNTTAAGTTTATTGATTATGAAAATA AAACTAANNTACANTGTCCTCGTTTGAGTTTAAAAAGAGTGGGAATGTAGGCTTTAATTT AGCAGAAATGGGGGTTACTTCTGAAACATNACTTGGTTTGCTTAATTCTAACAGACTTAT AAAATTTTTTTACCTTTCATCCCCAGAAAGGTAAATAGTTTTTGTTGGGGGGGAAAATTT AAAAAAGTAGGACCAACTGGGCATGGGGGGCTACTGGCTTTGAAATATATACCTGAGCAA A >OriGene 3' read for NM_021130 unedited
CGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAATGAAAAGAGTTTGATGTTTAT TTCCACCTTGCACTCAGGTCTGAGCCACAAGTACATTAAGACATTGAATGGTATCACCCA GGGAATACGTAACCAGACAACACACAAGACTGAGATGCACAAGTGGTGGTGGTGGTAATT CACGCAGAAGGAACCAGACAGTAAAACAAAAATTGCCCAACACACCAAATGATCAAATCC GCCACCTCTAGGATAGGCAAACTTGATTGCTGGGTTAAGAACCCTATAGGTCTGTTAAGG TGGGCAGAGAAGGGGTTTTCTCAGCTTATATTGTCCTGACATCTAACTGCCAGCAAGCAC TGTACATATAATTTCCTGAGAAACCAAGTCCTTAGTGGGAAGGGTATCCCTTTGACCAGA TCTTATGGCTTAAATTGGTCAGGTTTGCAAAACCTCAAAGCCTCCATAACCAAAGCTAGG GAGAGGCTCTATATGCTACAAGCAGTACCTCCTCACTGCAGGTAGTCTGCGCCTTAACCC TCTGCAGGGAGACTGACTGTAGCACCAAGTACCTGGCTTTTTAGACTCTACATAGGAATT CCACCATAATTAAGATGTATAAACTTGACCTACAGCCTATAGCCCAATATGCTTCCCTCA AGACATCAACAGTGTTCAAGCTTATCTTTGTTACAGAAAATGATGTAGGGTGCGGTGGCT CACATCTGTAATCTCANCAGTTTGGGAGGCCAAGGCAGGCGCATCAGCTGAGGTCAGAAG TTGAGACAGNCCTGTCAAATGATGAAACCCATCTTACTAACATACAAAAATAGCTGGGCA TGGTGCACACGCNCGTTATCCAGCTACTCAGAGCTGAGCACCAGATCACTTGATCCAGNA GCGGAGCTGCNTGANCTAAATACGCCATGCTTCAGGNATAAAATAAAAGAACGACAGAGT CTATTTTGAATAGCATCTGAAACACTTAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021130 |
| Insert Size | 2290 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021130.2, NP_066953.1 |
| RefSeq Size | 1652 bp |
| RefSeq ORF | 498 bp |
| Locus ID | 5478 |
| UniProt ID | P62937 |
| Domains | pro_isomerase |
| Gene Summary | This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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BMP-2/4 and BMP-6/7 Differentially Utilize Cell Surface Receptors to Induce Osteoblastic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells
,Karen Lavery, Pamela Swain, Dean Falb, and Moulay Hicham Alaoui-Ismaili,
J. Biol. Chem., Jul 2008; 283: 20948 - 20958.
[PPIA]
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BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow derived mesenchymal stem cells
,Karen S. Lavery, Pamela M. Swain, Dean Falb, and Moulay Hicham Alaoui-Ismaili,
J. Biol. Chem., Apr 2008; 10.1074/jbc.M800850200
[PPIA]
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GATA3 upregulation associated with surface expression of CD294/CRTH2: a unique feature of human Th cells
,Umberto De Fanis, Francesca Mori, Rebecca J. Kurnat, Won Kyung Lee, Maria Bova, N. Franklin Adkinson, Jr, Vincenzo Casolaro,
Blood. 2007 May 15;109(10):4343-50.
[PPIA]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203307 | PPIA (Myc-DDK-tagged)-Human peptidylprolyl isomerase A (cyclophilin A) (PPIA) |
CNY 1,800.00 |
|
| RC203307L1 | Lenti ORF clone of Human peptidylprolyl isomerase A (cyclophilin A) (PPIA), Myc-DDK-tagged |
CNY 4,200.00 |
|
| RC203307L2 | Lenti ORF clone of Human peptidylprolyl isomerase A (cyclophilin A) (PPIA), mGFP tagged |
CNY 4,200.00 |
|
| RC203307L3 | Lenti ORF clone of Human peptidylprolyl isomerase A (cyclophilin A) (PPIA), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203307L4 | Lenti ORF clone of Human peptidylprolyl isomerase A (cyclophilin A) (PPIA), mGFP tagged |
CNY 4,200.00 |
|
| RG203307 | PPIA (tGFP-tagged) - Human peptidylprolyl isomerase A (cyclophilin A) (PPIA) |
CNY 3,400.00 |
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