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PBR (TSPO) (NM_000714) Human Untagged Clone
CAT＃: SC111597
TSPO (untagged)-Human translocator protein (18kDa) (TSPO), transcript variant PBR
CNY 2,400.00
CNY 2,950.00
| Cited in 3 publications. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BPBS; BZRP; DBI; IBP; MBR; mDRC; PBR; PBS; pk18; PKBS; PTBR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111597 sequence for NM_000714 edited (data generated by NextGen Sequencing)
ATGGCCCCGCCCTGGGTGCCCGCCATGGGCTTCACGCTGGCGCCCAGCCTGGGGTGCTTC GTGGGCTCCCGCTTTGTCCACGGCGAGGGTCTCCGCTGGTACGCCGGCCTGCAGAAGCCC TCGTGGCACCCGCCCCACTGGGTGCTGGGCCCTGTCTGGGGCACGCTCTACTCAGCCATG GGGTACGGCTCCTACCTGGTCTGGAAAGAGCTGGGAGGCTTCACAGAGAAGGCTGTGGTT CCCCTGGGCCTCTACACTGGGCAGCTGGCCCTGAACTGGGCATGGCCCCCCATCTTCTTT GGTGCCCGACAAATGGGCTGGGCCTTGGTGGATCTCCTGCTGGTCAGTGGGGCGGCGGCA GCCACTACCGTGGCCTGGTACCAGGTGAGCCCGCTGGCCGCCCGCCTGCTCTACCCCTAC CTGGCCTGGCTGGCCTTCGCGACCACACTCAACTACTGCGTATGGCGGGACAACCATGGC TGGCGTGGGGGACGGCGGCTGCCAGAGTGA Clone variation with respect to NM_000714.4 439 a=>g >OriGene 5' read for NM_000714 unedited
CACGAGGGAGCGTGCCCTCGCCGCTGAGCTCCCCTNGACAGCAGCTGCAGCAGCCATGGC CCCGCCCTGGGTGCCCGCCATGGGCTTCACGCTGGCGCCCAGCCTGGGGTGCTTCGTGGG CTCCCGCTTTGTCCACGGCGAGGGTCTCCGCTGGTACGCCGGCCTGCAGAAGCCCTCGTG GCACCCGCCCCACTGGGTGCTGGGCCCTGTCTGGGGCACGCTCTACTCAGCCATGGGGTA CGGCTCCTACCTGGTCTGGAAAGAGCTGGGAGGCTTCACAGAGAAGGCTGTGGTTCCCCT GGGCCTCTACACTGGGCAGCTGGCCCTGAACTGGGCATGGCCCCCCATCTTCTTTGGTGC CCGACAAATGGGCTGGGCCTTGGTGGATCTCCTGCTGGTCAGTGGGGCGGCGGCAGCCAC TACCGTGGCCTGGTACCAGGTGAGCCCGCTGGCCGCCCGCCTGCTCTACCCCTACCTGGC CTGGCTGGCCTTCGCGACCACACTCAACTACTGCGTATGGCGGGACAACCATGGCTGGCG TGGGGGACGGCGGCTGCCAGAGTGAGTGCCCGGCCCACCAGGGACTGCAGCTGCACCAGC AGGTGCCATCACGCTTGNTGATGTGGTGGCCGTCACGCTTTCATGACCACTGGGCCTGCT AGTCTGTCAGGGCCTTGGCCCCAGGGTCAGCAGAGCTTCAGAGGTGGCCCCA >OriGene 3' read for NM_000714 unedited
TGATCAAAACTTTCTTCATCTTATAAAATTCCAGTTCCAGTACATGCTCTAAGCATGCAT AAAGCACAGGACACTGCTCCCGGGTGGGGGCTCATGTGGGGCCACCTCTGAAGCTCTGCT GACCCCTGGGCCAAGGCCCTGACAGACTATCAGGCCCAGTGGTCATGAAAGCGTGACGGC CACCACATCACAAGCGTGATGGCACCTGCTGGTGCAGCTGCAGTCCCTGGTGGGCCGGGC ACTCACTCTGGCAGCCGCCGTCCCCCACGCCATCCATGGTTGTCCCGCCATACGCAGTAG TTGAGTGTGGTCGCGAAGGCCAGCCAGGCCAGGTAGGGGTAGAGCAGGCGGGCGGCCAGC GGGCTCACCTGGTACCAGGCCACGGTAGTGGCTGCCGCCGCCCCACTGACCAGCATGAGA TCCACCAAGGCCCAGCCCATTTGTCGGGCACCAAAGAATATGGGGGGCCATGCCCAGTTC AGGGCCAGCTGCCCAGTGTAGAGGCCCAGGGGAACCACAGGCTTCTCTGTGAAGCCTCCC AGCTCTTTCCAGACCATGTAGGAGCCGTACCCCATGGCTGAGTAGATCGTGCCCCATACA GGGCCCATCACCCATTGGGGCCGGGTGCCACGATGGCCTTTTGTAAGCCGGCGTTCCAGC GGATGACCCCTCGCCGTGGACAAAGCGGGAGTCCACGAAGCACCCCAAGCTGGGCGCCAG CGTGAATCCATGGCGGGCACCCATGGCGGGGCCATGGCTGCAGCACCTGCTGTCACGGGA ACTTATCGGGGAAGGCCCTCTCCCCTCTGTGCCAATTCGCTGGCCGCCTTATAGTGAGCC CTCTTACAAAATCTGGTGGCTACCTAAAGAGCTCTGCTTTTTTAAACCCCCACGCTCAAC CCTACCGCCCATTGCCGTTAAGGGGGGGGGTTTTACAATTTTTGGAAGTCCCCTGACTCG GAGCCAAAATACTTCTTGACGCACG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000714 |
| Insert Size | 890 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000714.4, NP_000705.2 |
| RefSeq Size | 876 bp |
| RefSeq ORF | 510 bp |
| Locus ID | 706 |
| UniProt ID | P30536 |
| Domains | TspO_MBR |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012] Transcript Variant: This variant (PBR) consists of four exons and encodes the protein PBR. |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Modulation of systemic and mucosal immunity against an inactivated vaccine of Newcastle disease virus by oral co-administration of live attenuated Salmonellaenterica serovar Typhimurium expressing chicken interleukin-18 and interferon-α
,null,
The Journal of Veterinary Medical Science
,PubMed ID 25502364
[TSPO]
|
|
Targeting mitochondrial 18kDa Translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype
,Taylor, JM;Allen, AM;Graham, A;,
Clin. Sci.
,PubMed ID 24814875
[TSPO]
|
|
Translocator Protein 18 kDa Negatively Regulates Inflammation in Microglia
,Bae, KR;Shim, HJ;Balu, D;Kim, SR;Yu, SW;,
J Neuroimmune Pharmacol. April 2014
,PubMed ID 24687172
[TSPO]
|
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220107 | TSPO (Myc-DDK-tagged)-Human translocator protein (18kDa) (TSPO), transcript variant PBR |
CNY 2,400.00 |
|
| RC220107L1 | Lenti ORF clone of Human translocator protein (18kDa) (TSPO), transcript variant PBR, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC220107L2 | Lenti ORF clone of Human translocator protein (18kDa) (TSPO), transcript variant PBR, mGFP tagged |
CNY 4,800.00 |
|
| RC220107L3 | Lenti ORF clone of Human translocator protein (18kDa) (TSPO), transcript variant PBR, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC220107L4 | Lenti ORF clone of Human translocator protein (18kDa) (TSPO), transcript variant PBR, mGFP tagged |
CNY 5,890.00 |
|
| RG220107 | TSPO (tGFP-tagged) - Human translocator protein (18kDa) (TSPO), transcript variant PBR |
CNY 4,000.00 |
