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Beta TRCP (BTRC) (NM_033637) Human Untagged Clone
CAT＃: SC110015
BTRC (untagged)-Human beta-transducin repeat containing (BTRC), transcript variant 1
CNY 4,512.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BETA-TRCP; betaTrCP; bTrCP; bTrCP1; FBW1A; FBXW1; FBXW1A; FWD1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_033637 edited
GAATTCGGCACGAGGCCCCGGCGGAGAGCGGACCCAGTGGCCTCGGCGATTATGGACCCG GCCGAGGCGGTGCTGCAAGAGAAGGCACTCAAGTTTATGTGCTCTATGCCCAGGTCTCTG TGGCTGGGCTGCTCCAGCCTGGCGGACAGCATGCCTTCGCTGCGATGCCTGTATAACCCA GGGACTGGCGCACTCACAGCTTTCCAGAATTCCTCAGAGAGAGAAGACTGTAATAATGGC GAACCCCCTAGGAAGATAATACCAGAGAAGAATTCACTTAGACAGACATACAACAGCTGT GCCAGACTCTGCTTAAACCAAGAAACAGTATGTTTAGCAAGCACTGCTATGAAGACTGAG AATTGTGTGGCCAAAACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAA CGGAAACTCTCAGCAAGCTATGAAAAGGAAAAGGAACTGTGTGTCAAATACTTTGAGCAG TGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATATCCCAAATGTGTCATTAC CAACATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCT CTGCCAGCTCGGGGATTGGATCATATTGCTGAGAACATTCTGTCATACCTGGATGCCAAA TCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAGTGACCTCTGATGGCATG CTGTGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCA GAACGAAGAGGATGGGGACAGTATTTATTCAAAAACAAACCTCCTGACGGGAATGCTCCT CCCAACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAGACATTGAGACAATAGAA TCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGTGAAACAAGC AAAGGAGTTTACTGTTTACAGTATGATGATCAGAAAATAGTAAGCGGCCTTCGAGACAAC ACAATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAATTCTCACAGGCCATACA GGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCC ACGGTCAGAGTGTGGGATGTAAATACAGGTGAAATGCTAAACACGTTGATTCACCATTGT GAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGACCTGCTCCAAAGATCGT TCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTC GGACACCGAGCTGCTGTCAATGTTGTAGACTTTGATGACAAGTACATTGTTTCTGCATCT GGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAATTTGTAAGGACCTTAAAT GGACACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCA TCTGACAACACTATCAGATTATGGGACATAGAATGTGGTGCATGTTTACGAGTGTTAGAA GGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGAGGATAGTCAGTGGGGCC TATGATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCA GGGACACTCTGTCTACGGACCCTTGTGGAGCATTCCGGAAGAGTTTTTCGACTACAGTTT GATGAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCCTCATCTGGGACTTCCTA AATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATACACCTACATC TCCAGATAAATAACCATACACTGACCTCATACTTGCCCAGGACCCATTAAAGTTGCGGTA TTTAACGTATCTGCCAATACCAGGATGAGCAACAACAGTAACAATCAAACTACTGCCCAG TTTCCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTCTG CAGTCGGCCCAGGACGGTCTACTCAGCACAACTGACTGCTTCAGTGCTGCTATCAGAAGA TGTCTTCTATCTTTTGTGAATGATTGGAACTTTTAAACCTCCCCTCCTCTCCTCCTTTCA CCTCTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAG TGTTTTGCCAGAATCTCTCTTGCTTTGCCATTAAGCAGAAGAACTAGTTTCCCTGTATAG CCTGCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCTTCAAGCCCAGTGCCCAG TGTCTCCCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATAT GCTTAGGAGGAGACAGAGTTCCCTCTGTATAGCCTCTGGGACAAGAAAAAGAAAACACAA GAATGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTCTTTGTTTCTGTTCCTCT TCCCATCTACTCCCCTACGCCCCTTCAACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGA AAGTGTACGAAGAGAGTGTCCTCCTCTCACATGAGCCAGATCAGCCAGAAAATGCAACAC TTGGAAGAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGGCCTTTGCTGCAAGTGAC CCTGTGGCAACAGTGGATTCTCAGACATGATACTCTCATCATATTTGCAACTCTTCTCTC TCTTTCTTCCCCACACCCAAGAGGAGGATTGGTGGTAGGGGGCAGGCAGAGGGGGTGGGG AGAAGTTTCCTGGGCTCCATCAATGGCTGCATCTTTTCTGGACTCAGCAGTCTCCTTGAT TCCATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGTGT GTAATAAAAAGCATTGTACTTCATCTTAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_033637 unedited
GCACATTTTGTAATACGACTCACTATAGGGCGGCCGCGAAATTCGCACGAGGCCCCGGCG GAGAGCGGACCCAGTGGCCTCGGCGATTATGGACCCGGCCGAGGCGGTGCTGCAAGAGAA GGCACTCAAGTTTATGTGCTCTATGCCCAGGTCTCTGTGGCTGGGCTGCTCCAGCCTGGC GGACAGCATGCCTTCGCTGCGATGCCTGTATAACCCAGGGACTGGCGCACTCACAGCTTT CCAGAATTCCTCAGAGAGAGAAGACTGTAATAATGGCGAACCCCCTAGGAAGATAATACC AGAGAAGAATTCACTTAGACAGACATACAACAGCTGTGCCAGACTCTGCTTAAACCAAGA AACAGTATGTTTAGCAAGCACTGCTATGAAGACTGAGAATTGTGTGGCCAAAACAAAACT TGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGGAAACTCTCAGCAAGCTATGA AAAGGAAAAGGAACTGTGTGTCAAATACTTTGAGCAGTGGTCAGAGTCAGATCAAGTGGA ATTTGTGGAACATCTTATATCCCAAATGTGTCATTACCAACATGGGCACATAAACTCGTA TCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTGCCAGCTCGGGGATTGGATCA TATTGCTGAGAACATTCTGTCATACCTGGATGCCAAATCACTATGTGCTGCTGAACTTGT GTGCAAGGAATGGTACCGAGTGACCTCTGATGGCATGCTGTGGAAGAAGCTTATCGAGAG AATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAACGAAAAGGATGGGGACAGTA TTTATTCAAAAACAACCTCCTGACGGGAATGCNTCTCCCACTCTTNTATAGAGCACTTAT CCTAAAATATACCAGACATTGAGACATAGAATCTATGGNAG >OriGene 3' read for NM_033637 unedited
CAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAAAATGAAGTACAATGCTTTTTATT ACACACCCAATTGTTAATGAGAGGAAATGCAATCAGCAACTCCTTTCCACACTCTACATG GAATCAAGGAGACTGCTGAGTCCAGAAAAGATGCAGCCATTGATGGAGCCCAGGAAACTT CTCCCCACCCCCTCTGCCTGCCCCCTACCACCAATCCTCCTCTTGGGTGTGGGGAAGAAA GAGAGAGAAGAGTTGCAAATATGATGAGAGTATCATGTCTGAGAATCCACTGTTGCCACA GGGTCACTTGCAGCAAAGGCCTGGGGCTGAAATCTTCACTGAACAGCATTTAACTCTTCC AAGTGTTGCATTTTCTGGCTGATCTGGCTCATGTGAGAGGAGGACACTCTCTTCGTACAC TTTCTTCTCAGGTGAAGCAGACAGAGAAAAAAGGTTGAAGGGGCGTAGGGGAGTATATGG GAAGAGGAACAGAAACAAAGAGAAGGCAGGCAGGAGGCCCAAATCTTCCAGTGTATACAT TCTTGAGTTTTCTTTTTCTTGTCCCAGAGGCTATACAGAGGGAACTCTGTCTCCTCCTAA GCATATTGAGGCTGGGCTGCTCTGGCCAGGTGCTTGGCATTCCTGCAGTTAACAGGGAGA CACTGGGCACTGGNGCTGAAGCTGCATCCCCCATACCCTAGAAGTGGGTCTCTCCCAGCA GCTATACAGGGAAACTAGTTCTTCTGCTTAATGGCAATGCAGAGAGATCCTGGCAAAACA CTAAATATATCTATAAGTCACCTTTNGTCTGGACAATGGGNAATAACTTAGTGCCAAGTG AAAGAGGAAAAGAGGGAGGTTTAAAAGTTCCATCATCCCAAAGAATAAGACTCTCCGAAA CAGCCTGAGCATCAGGTGGCTGATAAACGTCTGGGCGACTGANACACTGGTCCAAAAGGT CCTAAGCCGCTCTCGCTTTCAGGAACTGCACTATTGTGTCCTGTGTGTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_033637 |
| Insert Size | 3270 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033637.2, NP_378663.1 |
| RefSeq Size | 6146 bp |
| RefSeq ORF | 1818 bp |
| Locus ID | 8945 |
| UniProt ID | Q9Y297 |
| Domains | WD40, F-box |
| Protein Families | Druggable Genome |
| Protein Pathways | Hedgehog signaling pathway, Oocyte meiosis, Ubiquitin mediated proteolysis, Wnt signaling pathway |
| Gene Summary | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6. [provided by RefSeq, Mar 2012] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207025 | BTRC (Myc-DDK-tagged)-Human beta-transducin repeat containing (BTRC), transcript variant 1 |
CNY 4,504.00 |
|
| RC207025L1 | Lenti ORF clone of Human beta-transducin repeat containing (BTRC), transcript variant 1, Myc-DDK-tagged |
CNY 6,904.00 |
|
| RC207025L2 | Lenti ORF clone of Human beta-transducin repeat containing (BTRC), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC207025L3 | Lenti ORF clone of Human beta-transducin repeat containing (BTRC), transcript variant 1, Myc-DDK-tagged |
CNY 6,904.00 |
|
| RC207025L4 | Lenti ORF clone of Human beta-transducin repeat containing (BTRC), transcript variant 1, mGFP tagged |
CNY 6,904.00 |
|
| RG207025 | BTRC (tGFP-tagged) - Human beta-transducin repeat containing (BTRC), transcript variant 1 |
CNY 6,104.00 |
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