United States
Germany
Japan
United Kingdom
China
DUSP7 (NM_001947) Human Untagged Clone
CAT＃: SC104259
DUSP7 (untagged)-Human dual specificity phosphatase 7 (DUSP7)
CNY 3,656.00
CNY 6,750.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MKPX; PYST2 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC104259 sequence for NM_001947 edited (data generated by NextGen Sequencing)
ATGAAAAACCAGCTCCGCGGCCCCCCAGCGCGGGCGCACATGTCGACTTCGGGGGCGGCG GCGGCTGGGGGCACCCGGGCGGGGTCCGAGCCCGGTGCGGGGTCGGGGTCCGGCGCAGGC ACCGGGGCGGGCGCGGCGACGGGGGCAGGGGCCATGCCCTGCAAGAGCGCCGAGTGGCTG CAGGAGGAGCTGGAGGCGCGCGGCGGCGCGTCCTTGCTGCTGCTCGACTGCCGGCCGCAC GAGCTCTTCGAGTCGTCGCACATCGAGACGGCCATCAACCTGGCCATCCCGGGCCTCATG TTGCGCCGCCTGCGCAAGGGCAACCTGCCCATCCGCTCCATCATCCCCAACCACGCCGAC AAGGAGCGCTTCGCCACGCGCTGCAAGGCGGCCACCGTGCTGCTCTACGACGAGGCCACG GCCGAGTGGCAGCCCGAGCCCGGCGCTCCCGCCTCCGTGCTCGGCCTGCTCCTACAGAAG CTGCGCGACGACGGCTGCCAGGCCTACTACCTCCAAGGTGGTTTCAACAAGTTTCAAACA GAGTACTCTGAGCACTGCGAGACCAACGTGGACAGCTCTTCCTCGCCGAGCAGCTCGCCA CCCACCTCAGTGCTGGGCCTGGGGGGCCTGCGCATCAGCTCTGACTGCTCCGACGGCGAG TCGGACCGAGAGCTGCCCAGCAGTGCCACCGAGTCAGACGGCAGCCCTGTGCCATCCAGC CAACCAGCCTTCCCTGTCCAGATCCTGCCCTACCTCTACCTCGGCTGCGCCAAGGACTCC ACCAACCTGGACGTGCTCGGCAAGTATGGCATCAAGTATATCCTCAATGTCACACCCAAC CTACCCAACGCCTTCGAGCACGGCGGCGAGTTCACCTACAAGCAGATCCCCATCTCTGAC CACTGGAGCCAGAACCTCTCCCAGTTCTTCCCTGAGGCCATCAGCTTCATTGACGAAGCC CGCTCCAAGAAGTGTGGTGTCCTGGTGCACTGCCTGGCAGGCATCAGCCGCTCAGTGACG GTCACTGTGGCCTATCTGATGCAGAAGATGAACCTGTCACTCAACGACGCCTACGACTTT GTCAAGAGGAAAAAGTCCAACATCTCGCCCAACTTCAACTTCATGGGGCAGCTGCTGGAC TTTGAGCGGACGCTGGGGCTAAGCAGCCCGTGCGACAACCACGCGTCGAGTGAGCAGCTC TACTTTTCCACGCCCACCAACCACAACCTGTTCCCACTCAATACGCTGGAGTCCACGTGA Clone variation with respect to NM_001947.3 >OriGene 5' read for NM_001947 unedited
CCGCCCCGTTGCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCT CATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCG GCACGAGGGCGGCTGGGGCCCGCGCGGCCGGGGCGCCGTCCCAGGGCAGGGCTGCCCGGC CCCGGCCCCGGGCCGCCCGCGCTCCCCATGAAAAACCAGCTCCGCGGCCCCCCAGCGCGG GCGCACATGTCGACTTCGGGGGCGGCGGCGGCTGGGGGCACCCGGGCGGGGTCCGAGCCC GGTGCGGGGTCGGGGTCCGGCGCAGGCACCGGGGCGGGCGCGGCGACGGGGGCAGGGGCC ATGCCCTGCAAGAGCGCCGAGTGGCTGCAGGAGGAGCTGGAGGCGCGCGGCGGCGCGTCC TTGCTGCTGCTCGACTGCCGGCCGCACGAGCTCTTCGAGTCGTCGCACATCGAGACGGCC ATCAACCTGGCCATCCCGGGCCTCATGTTGCGCCGCCTGCGCAAGGGCAACCTGCCCATC CGCTCCATCATCCCCAACCACGCCGACAAGGAGCGCTTCGCCACGCGCTGCAAGGCGGCC ACCGTGCTGCTCTACGACGAGGCCACGGCCGAGTGGCAGCCCGAGCCCGGCGCTCCCGCC TCCGTGCTCGGCCTGCTCCTACAGAAGCTGCGCGACGACGGCTGCCAGGCCTACTACCTN CAAGGTGGNTTCAACAAGTTTCAAACAGAGTACTCTGAGCACTGCGAGACCAACGTGGAC AGCTCTTCCTCGCCGAGCAGCTCGCCACCCACCTCAGTGCTGGGCCTGGNGGGCCTGCGC ATCAGCTCTGACTGCTCCGACGGCGAGTCGGACCGAGAGCTGNCCAGCAGTGCCACCGAG TCAGACGGNAGNCCTGTGCCATNCAGNCACCAGNCTTTCTGTNNCAGANNCTGCCTACTC NNTACTCGNTGNGCCAGGACTCACAACCCTGGACTGCTCGGNNAGT >OriGene 3' genomic read for NM_001947 unedited
NCTANGATCGATTTTTTTTTTTTTTTTTTAAAGAAAAAAAATATTTATTTGCAATATAAA CAAAGTCCCGTTGTTGGTTCGGGATATATATATATATGTATGTGTGTGTATATATATACG TAGGGTCACAAATCTTCCTTCATAAGATCATAAAGCAAAACTGGCCACCTTCTGGCATAC CCTCATTTACACAAATCTGGTACATCTTTCTGGGTTTTCTTTTTAAAAATAAAAGAGAGA AAAAGAGAACCATGTACAGCATGGAAGCTTGTTGTCAATTTCTCGACTGTGGCAAGATTT TAATCTGCTGCGCTAAAGAATCCCTGAAAGCCACCCCCGTGAGGTAAGAAGCAGTGGGGC AGAGTTTTTCTGTGGCCTCACTCACATGCTGAGTGCTGCTCCGTCAGGGACCCTGGCCTG ACTCCTCTGCCTGCCCCAGGCCCCCATGCAGTCCTGACACCTGGTGGAACTGAGGCTGGA GAAGGAACAAAACTGGAGGAAGATAACGGAATCCGTGGCTTCGTTCTGTGGAGGCAGGGG GAAGTGAACAGAGCCTTACCCCCCTTCTGCTGGTCCATCCTTGCCCCACTTGCCCCCGCC CTAAGGTTGAAATGGGTGCAAGTCTCCTGGCATTAAAAAGCATGGGCAAAATGAAGGCAG GGCAAGCTTCCAAGGGGACAGGGGGCTGGGAGGGCCCCACCAAAACACCGCCTGGGGAAA AGAAGAACCTGGAGGTCCGGCTGGGGCCCCACCCCTAATGTCTCCCCAGCCCCTGGGGCC TCCCTCCCCGTTTCCCACCNNNAAAGAGGAAGGGAAAAAAAAGGGCGGGGGGGAAAAAAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001947 |
| Insert Size | 3500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001947.1, NP_001938.1 |
| RefSeq Size | 1107 bp |
| RefSeq ORF | 1107 bp |
| Locus ID | 1849 |
| UniProt ID | Q16829 |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7
,James Chappell, Yuhua Sun, Amar Singh, and Stephen Dalton,
Genes & Dev., Apr 2013; 27: 725 - 733.
,PubMed ID 23592794
[DUSP7]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211190 | DUSP7 (Myc-DDK-tagged)-Human dual specificity phosphatase 7 (DUSP7) |
CNY 3,656.00 |
|
| RC211190L3 | Lenti-ORF clone of DUSP7 (Myc-DDK-tagged)-Human dual specificity phosphatase 7 (DUSP7) |
CNY 5,890.00 |
|
| RC211190L4 | Lenti-ORF clone of DUSP7 (mGFP-tagged)-Human dual specificity phosphatase 7 (DUSP7) |
CNY 5,890.00 |
|
| RG211190 | DUSP7 (tGFP-tagged) - Human dual specificity phosphatase 7 (DUSP7) |
CNY 4,370.00 |
|
| SC327842 | DUSP7 (untagged)-Human dual specificity phosphatase 7 (DUSP7) |
CNY 6,750.00 |
