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Csk (NM_001030039) Rat Untagged Clone
CAT＃: RN202254
Csk (untagged ORF) - Rat c-src tyrosine kinase (Csk), (10 ug)
CNY 5,800.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | MGC112926 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN202254 representing NM_001030039
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCGGCTATACAGGCCTCCTGGCCATCCGGTACAGAATGTATTGCCAAGTACAACTTCCATGGCACTG CCGAGCAAGACCTTCCCTTCTGCAAAGGAGATGTGCTCACCATTGTGGCTGTCACCAAGGACCCCAACTG GTACAAAGCCAAAAACAAAGTGGGCCGTGAGGGCATCATCCCAGCCAACTATGTCCAGAAGCGTGAGGGT GTGAAGGCAGGCACCAAGCTCAGCCTTATGCCCTGGTTCCACGGCAAGATCACACGGGAGCAGGCGGAGC GGCTTCTCTACCCACCAGAGACAGGCCTGTTCCTGGTGCGGGAAAGCACCAACTACCCTGGGGACTACAC ACTGTGTGTGAGCTGTGAAGGCAAGGTGGAGCACTACCGCATCATGTATCACGCGAGCAAGCTGAGCATT GATGAGGAGGTGTACTTCGAGAACCTCATGCAGCTGGTGGAGCACTACACCACAGATGCCGACGGACTCT GCACTCGCCTCATCAAACCAAAGGTCATGGAGGGCACAGTGGCGGCCCAAGATGAATTCTACCGCAGTGG CTGGGCCCTGAACATGAAGGAACTGAAGCTGCTACAGACGATAGGAAAGGGGGAGTTTGGAGATGTGATG CTGGGGGATTACCGAGGCAACAAAGTTGCAGTCAAGTGCATTAAGAATGATGCTACAGCCCAGGCCTTCC TGGCTGAAGCCTCTGTCATGACGCAGCTTCGGCACAGCAACCTAGTCCAGCTACTGGGTGTGATTGTGGA GGAGAAGGGTGGGCTCTACATCGTCACAGAGTACATGGCCAAGGGGAGTTTGGTGGACTATCTTCGATCA CGTGGTCGTTCGGTGCTAGGCGGAGACTGTCTCCTCAAATTCTCACTAGACGTCTGTGAAGCCATGGAGT ACCTGGAGGGTAACAATTTTGTGCACCGGGACTTGGCTGCCCGGAATGTGCTGGTGTCTGAGGACAACGT GGCCAAAGTCAGTGACTTTGGCCTCACTAAGGAAGCTTCCAGCACTCAGGACACAGGCAAACTGCCAGTC AAGTGGACAGCTCCTGAAGCCTTGAGAGAGAAGAAATTTTCCACCAAGTCTGATGTGTGGAGTTTCGGAA TCCTTCTCTGGGAAATCTATTCCTTCGGGCGAGTGCCTTACCCAAGAATTCCCCTGAAGGACGTCGTCCC TCGGGTGGAAAAGGGCTATAAGATGGACGCTCCGGATGGCTGCCCACCCGCAGTCTATGATGTTATGAAG AACTGCTGGCACCTGGATGCTGCCACGCGGCCCACCTTTCTGCAGCTTCGAGAGCAGCTCGAGCACATCA GAACCCATGAGCTGCACCTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001030039 |
| Insert Size | 1353 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001030039.1, NP_001025210.1 |
| RefSeq Size | 2108 bp |
| RefSeq ORF | 1353 bp |
| Locus ID | 315707 |
| UniProt ID | P32577 |
| Gene Summary | Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN, CSK or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR202254 | Csk (Myc-DDK-tagged ORF) - Rat c-src tyrosine kinase (Csk), (10 ug) |
CNY 5,800.00 |
|
| RR202254L3 | Lenti ORF clone of Csk (Myc-DDK-tagged ORF) - Rat c-src tyrosine kinase (Csk), (10 ug) |
CNY 7,700.00 |
|
| RR202254L4 | Lenti ORF clone of Csk (mGFP-tagged ORF) - Rat c-src tyrosine kinase (Csk), (10 ug) |
CNY 8,460.00 |
