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BAZ2A (NM_001300905) Human Tagged ORF Clone
CAT＃: RG240221
- TrueORF®
BAZ2A (tGFP-tagged) - Human bromodomain adjacent to zinc finger domain, 2A (BAZ2A), transcript variant 2
ORF Plasmid: DDK
"NM_001300905" in other vectors (2)
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CNY 19,370.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | TIP5; WALp3 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG240221 representing NM_001300905.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAGGCAAACGACCATTTTAACTTTACTGGCCTTCCCCCTGCACCTGCTGCCTCAGGACTGAAACCC TCTCCTTCCTCAGGGGAGGGCCTCTACACTAACGGGTCTCCCATGAACTTCCCCCAGCAAGGGAAAAGT TTGAATGGGGATGTGAATGTTAATGGCTTATCTACTGTATCTCACACTACTACTTCAGGGATTTTGAAC TCTGCTCCCCACTCCTCCAGCACCTCACACCTCCATCACCCCAGCGTGGCCTACGACTGTCTCTGGAAC TACTCACAGTACCCATCTGCCAATCCTGGCAGCAACCTCAAGGACCCACCCCTTCTCTCCCAGTTCTCG GGGGGACAATACCCACTCAACGGCATCCTTGGGGGCAGCCGGCAACCTTCATCCCCAAGTCATAACACT AACCTTCGGGCTGGGAGCCAAGAGTTCTGGGCCAACGGTACCCAGAGTCCCATGGGGCTTAACTTTGAT TCACAAGAACTGTATGATTCCTTTCCTGACCAGAATTTTGAGGTGATGCCCAATGGACCCCCTAGTTTT TTCACCTCCCCACAGACTTCTCCTATGTTGGGATCTAGCATTCAAACCTTTGCACCCTCCCAGGAGGTA GGCAGTGGTATCCATCCTGATGAGGCAGCAGAAAAGGAGATGACTTCAGTTGTGGCAGAGAATGGCACT GGCTTGGTAGGCAGCTTGGAGCTGGAAGAAGAGCAGCCAGAACTGAAGATGTGTGGCTACAATGGCTCT GTCCCTTCTGTGGAATCGTTACACCAAGAGGTCTCAGTCCTGGTCCCTGACCCCACAGTGAGCTGTTTA GATGATCCTTCACATCTTCCTGATCAACTGGAAGACACTCCAATCCTCAGTGAAGACTCTCTGGAGCCC TTCAACTCTCTGGCACCAGAGCCAGTGAGTGGAGGACTATATGGTATTGATGACACGGAGCTGATGGGT GCAGAGGACAAGCTGCCTCTTGAGGACAGCCCTGTGATTTCTGCCCTTGATTGCCCTTCCCTCAATAAT GCTACTGCCTTCAGTCTCCTGGCAGATGATAGTCAAACATCAACCTCTATCTTTGCCAGTCCCACCTCT CCACCTGTCCTAGGGGAGTCTGTCCTGCAAGATAACAGCTTTGACCTGAATAATGGTAGTGACGCTGAA CAGGAAGAAATGGAAACTCAATCTTCAGACTTCCCACCATCCCTGACCCAGCCAGCTCCTGATCAGTCA TCCACTATTCAGCTACATCCAGCAACCTCACCAGCAGTCTCGCCAACAACCTCCCCAGCAGTCTCCCTA GTGGTTTCTCCAGCAGCCTCCCCAGAAATCTCTCCAGAAGTTTGTCCCGCAGCTTCTACAGTTGTCTCT CCAGCAGTCTTCTCAGTGGTCTCTCCAGCTTCCTCAGCAGTCCTCCCAGCAGTCTCCTTAGAAGTCCCG TTGACGGCTTCAGTGACATCCCCAAAAGCCTCTCCCGTAACTTCCCCAGCAGCTGCCTTTCCAACAGCC TCCCCAGCAAATAAGGATGTCAGCAGCTTTCTAGAAACCACTGCTGACGTGGAAGAGATCACTGGAGAA GGACTCACTGCTTCTGGTAGTGGTGATGTCATGAGGAGACGTATTGCTACCCCAGAAGAAGTTCGTCTT CCCCTCCAACATGGGTGGCGGAGAGAGGTGCGCATCAAGAAGGGCAGCCACCGATGGCAGGGGGAGACC TGGTATTATGGCCCCTGTGGGAAGAGGATGAAGCAATTTCCAGAAGTGATCAAGTACCTGAGCCGCAAC GTGGTACACAGTGTCCGCCGAGAGCACTTCAGCTTCAGTCCCCGTATGCCTGTTGGAGATTTCTTTGAA GAAAGAGACACGCCAGAGGGCTTGCAGTGGGTGCAGCTCTCAGCAGAGGAGATCCCGTCGAGGATTCAG GCAATTACTGGCAAACGGGGTCGACCTCGAAACACTGAGAAGGCTAAGACTAAGGAAGTCCCCAAGGTG AAACGGGGTCGAGGTCGGCCACCTAAGGTCAAAATCACTGAGCTATTGAACAAGACAGACAACCGCCCC CTAAAGAAACTGGAGGCCCAAGAAACATTGAATGAGGAGGATAAAGCAAAGATTGCTAAAAGCAAGAAG AAGATGAGGCAGAAGGTTCAACGGGGAGAGTGTCAGACTACTATCCAAGGGCAGGCCAGAAATAAGCGG AAACAAGAGACCAAGAGCTTAAAGCAGAAGGAAGCTAAGAAGAAATCCAAGGCTGAGAAAGAAAAAGGA AAGACAAAGCAGGAAAAACTGAAGGAAAAAGTCAAGAGGGAAAAGAAGGAGAAGGTAAAAATGAAGGAA AAGGAGGAGGTGACCAAAGCCAAGCCAGCCTGTAAAGCAGATAAGACCCTGGCCACACAGAGGCGCTTG GAGGAACGGCAGAGGCAGCAGATGATCTTGGAGGAAATGAAGAAGCCGACAGAGGATATGTGTCTGACT GACCACCAGCCCCTGCCTGACTTCTCACGAGTCCCTGGTCTGACATTGCCCAGTGGAGCCTTCTCAGAC TGCTTGACCATTGTGGAGTTCCTGCATAGCTTTGGCAAGGTGCTGGGCTTTGATCCTGCCAAAGATGTG CCTAGCCTGGGGGTCCTGCAGGAGGGACTCCTGTGTCAAGGTGACAGCTTGGGTGAGGTGCAAGACCTG CTGGTCAGGCTGCTGAAGGCTGCACTCCATGATCCTGGCTTTCCCTCCTACTGTCAGTCCCTAAAGATC TTGGGGGAGAAGGTGTCTGAGATCCCACTGACAAGAGACAATGTGTCAGAGATCCTGCGCTGCTTCCTT ATGGCATATGGAGTAGAGCCAGCCCTCTGTGACCGCCTGCGCACCCAGCCTTTTCAGGCCCAGCCACCC CAGCAGAAGGCTGCTGTCCTGGCCTTCCTTGTGCATGAGCTCAATGGCTCCACCCTCATCATCAATGAG ATTGACAAGACTCTGGAGAGTATGTCCAGCTACAGGAAAAACAAGTGGATTGTTGAAGGCCGGCTCCGG AGGCTGAAAACTGTTCTGGCCAAGCGAACTGGGCGGTCTGAAGTAGAGATGGAAGGGCCAGAGGAATGC CTGGGACGGAGGCGCAGTTCTCGGATCATGGAGGAGACCAGTGGCATGGAAGAAGAGGAAGAAGAGGAG TCTATAGCAGCTGTCCCTGGCCGCAGGGGTCGAAGAGATGGAGAGGTTGATGCCACAGCATCTAGCATC CCAGAGCTAGAGCGCCAGATAGAAAAACTCAGCAAGCGTCAGCTTTTCTTTCGCAAAAAGCTGCTTCAC TCATCCCAGATGCTTCGGGCGGTCTCCCTGGGTCAGGACCGCTACAGACGTCGCTACTGGGTATTGCCG TATTTGGCTGGTATCTTTGTAGAAGGAACAGAGGGGAACTTAGTTCCTGAGGAGGTGATAAAGAAGGAA ACTGACTCCTTAAAAGTGGCAGCCCATGCGTCACTCAACCCTGCCCTCTTCTCTATGAAGATGGAGTTA GCTGGCTCCAACACCACTGCCAGTTCTCCTGCCCGGGCCCGAGGCCGACCTCGAAAAACTAAGCCCGGG TCTATGCAACCTAGGCATCTTAAGTCCCCTGTCAGGGGTCAGGATTCAGAACAGCCCCAGGCCCAGCTT CAGCCTGAGGCTCAGCTTCATGCTCCTGCCCAGCCCCAGCCTCAGCTTCAGCTTCAGCTTCAGTCCCAT AAGGGGTTCCTGGAGCAAGAAGGCTCCCCTTTGTCACTGGGTCAGAGCCAGCATGACCTCAGCCAGTCA GCCTTCCTGTCTTGGCTGAGCCAGACTCAGAGCCATAGCTCCCTGTTGAGCAGCTCAGTCCTCACACCT GATAGCAGTCCGGGAAAACTAGACCCAGCTCCATCACAACCCCCGGAGGAGCCAGAGCCTGATGAGGCA GAATCCAGCCCTGATCCTCAAGCACTCTGGTTTAACATCTCAGCCCAGATGCCCTGCAATGCTGCCCCC ACACCGCCCCCTGCAGTTTCTGAGGACCAACCCACTCCCTCCCCTCAGCAGCTTGCCTCCTCCAAGCCA ATGAATAGACCTAGTGCTGCCAACCCTTGTTCTCCAGTGCAGTTCTCTTCCACGCCCTTGGCTGGGTTG GCCCCTAAGAGGCGAGCAGGAGACCCTGGAGAAATGCCACAGAGTCCCACAGGGCTGGGACAGCCCAAA CGGAGAGGGAGACCTCCCAGTAAGTTCTTCAAACAGATGGAACAGCGTTACCTAACCCAGCTGACAGCC CAGCCTGTCCCACCTGAGATGTGCTCAGGCTGGTGGTGGATACGAGATCCTGAGATGTTGGATGCCATG CTCAAGGCCCTACACCCCCGAGGTATCCGGGAGAAGGCACTTCACAAACACCTTAACAAGCACAGGGAC TTCTTGCAGGAAGTCTGCCTGCGGCCCTCAGCTGACCCCATCTTTGAGCCCAGGCAACTACCTGCCTTT CAAGAAGGGATTATGAGCTGGTCCCCCAAAGAGAAGACATACGAGACAGACCTAGCAGTGCTTCAATGG GTAGAGGAGCTGGAGCAGCGGGTTATCATGTCTGATCTGCAGATTCGGGGCTGGACATGTCCTAGCCCA GACTCTACCCGTGAAGACTTGGCCTACTGTGAGCACCTCTCCGACTCCCAGGAGGATATCACCTGGCGA GGTCGGGGCAGGGAGGGACTGGCACCTCAGCGTAAAACTACCAACCCTTTGGACCTGGCTGTGATGCGG CTGGCTGCCCTGGAACAGAATGTAGAACGGCGGTACCTGCGGGAGCCCCTCTGGCCAACTCATGAGGTT GTGCTGGAGAAGGCCCTGCTTAGCACACCTAATGGTGCCCCTGAGGGCACCACTACAGAGATATCATAT GAGATCACCCCTCGCATTCGTGTCTGGCGCCAGACCCTCGAGCGGTGCCGGAGCGCAGCCCAGGTGTGC TTGTGCCTGGGCCAGCTGGAGAGGTCCATTGCCTGGGAGAAGTCTGTCAACAAAGTGACATGTCTAGTC TGCCGGAAGGGTGACAATGATGAGTTTCTTCTGCTTTGTGATGGGTGTGACCGTGGCTGCCACATTTAC TGCCATCGTCCCAAGATGGAGGCTGTCCCAGAAGGAGATTGGTTCTGTACTGTCTGTTTGGCTCAGCAG GTGGAGGGAGAATTCACTCAGAAGCCTGGTTTCCCAAAGCGTGGCCAGAAGCGGAAAAGTGGTTATTCG CTGAACTTCTCAGAGGGTGATGGCCGCCGACGCCGGGTACTGTTGAGGGGCCGAGAAAGCCCAGCAGCA GGGCCTCGGTACTCGGAAGAAGGGCTCTCCCCCTCCAAGCGGCGGCGACTCTCTATGCGGAACCACCAC AGTGATCTCACATTTTGCGAGATTATCCTGATGGAGATGGAGTCCCATGATGCAGCCTGGCCTTTCCTA GAGCCTGTGAACCCACGTTTGGTGAGTGGGTACCGGCGCATCATCAAAAATCCTATGGATTTTTCCACC ATGCGGGAGCGGCTGCTCAGGGGAGGGTACACCAGCTCAGAGGAGTTTGCGGCTGATGCCCTCCTGGTA TTTGACAACTGCCAGACTTTCAACGAGGATGACTCTGAAGTAGGCAAGGCTGGGCACATCATGCGCCGC TTCTTCGAGAGCCGCTGGGAGGAGTTTTATCAGGGAAAACAGGCCAATCTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG240221
Blue=ORF Red=Cloning site Green=Tag(s) MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLSTVSHTTTSGILN SAPHSSSTSHLHHPSVAYDCLWNYSQYPSANPGSNLKDPPLLSQFSGGQYPLNGILGGSRQPSSPSHNT NLRAGSQEFWANGTQSPMGLNFDSQELYDSFPDQNFEVMPNGPPSFFTSPQTSPMLGSSIQTFAPSQEV GSGIHPDEAAEKEMTSVVAENGTGLVGSLELEEEQPELKMCGYNGSVPSVESLHQEVSVLVPDPTVSCL DDPSHLPDQLEDTPILSEDSLEPFNSLAPEPVSGGLYGIDDTELMGAEDKLPLEDSPVISALDCPSLNN ATAFSLLADDSQTSTSIFASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQS STIQLHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAVSLEVP LTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEGLTASGSGDVMRRRIATPEEVRL PLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRNVVHSVRREHFSFSPRMPVGDFFE ERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEKAKTKEVPKVKRGRGRPPKVKITELLNKTDNRP LKKLEAQETLNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEKEKG KTKQEKLKEKVKREKKEKVKMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLT DHQPLPDFSRVPGLTLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDL LVRLLKAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRTQPFQAQPP QQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVLAKRTGRSEVEMEGPEEC LGRRRSSRIMEETSGMEEEEEEESIAAVPGRRGRRDGEVDATASSIPELERQIEKLSKRQLFFRKKLLH SSQMLRAVSLGQDRYRRRYWVLPYLAGIFVEGTEGNLVPEEVIKKETDSLKVAAHASLNPALFSMKMEL AGSNTTASSPARARGRPRKTKPGSMQPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSH KGFLEQEGSPLSLGQSQHDLSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPPEEPEPDEA ESSPDPQALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTPLAGL APKRRAGDPGEMPQSPTGLGQPKRRGRPPSKFFKQMEQRYLTQLTAQPVPPEMCSGWWWIRDPEMLDAM LKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPIFEPRQLPAFQEGIMSWSPKEKTYETDLAVLQW VEELEQRVIMSDLQIRGWTCPSPDSTREDLAYCEHLSDSQEDITWRGRGREGLAPQRKTTNPLDLAVMR LAALEQNVERRYLREPLWPTHEVVLEKALLSTPNGAPEGTTTEISYEITPRIRVWRQTLERCRSAAQVC LCLGQLERSIAWEKSVNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQ VEGEFTQKPGFPKRGQKRKSGYSLNFSEGDGRRRRVLLRGRESPAAGPRYSEEGLSPSKRRRLSMRNHH SDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLV FDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQANL TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001300905 |
| ORF Size | 5709 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001300905.2 |
| RefSeq Size | 8943 bp |
| RefSeq ORF | 5712 bp |
| Locus ID | 11176 |
| Protein Families | Druggable Genome |
| MW | 211.4 kDa |
| Gene Summary | Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity).[UniProtKB/Swiss-Prot Function] |
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