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Uromucoid (UMOD) (NM_001278614) Human Tagged ORF Clone
CAT＃: RG239282
- TrueORF®
UMOD (tGFP-tagged) - Human uromodulin (UMOD), transcript variant 3
ORF Plasmid: DDK
"NM_001278614" in other vectors (2)
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CNY 6,180.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | ADMCKD2; ADTKD1; FJHN; HNFJ; HNFJ1; MCKD2; THGP; THP |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG239282 representing NM_001278614.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGGCAGCCATCTCTGACTTGGATGCTGATGGTGGTGGTGGCCTCTTGGTTCATCACAACTGCAGCC ACTGACACCTCAGAAGCAAGAACAAAGTACAACTGCCCAGCCAGGTGGAGTTGGAGGACTCCGCAGAGA GGAGGCGACACTGAGCAGGGTCCTGATGAAGATTTCACCAGCCAGGGAAGATGGTGCTCTGAATGTCAC AGCAATGCCACCTGCACGGAGGATGAGGCCGTTACGACGTGCACCTGTCAGGAGGGCTTCACCGGCGAT GGCCTGACCTGCGTGGACCTGGATGAGTGCGCCATTCCTGGAGCTCACAACTGCTCCGCCAACAGCAGC TGCGTAAACACGCCAGGCTCCTTCTCCTGCGTCTGCCCCGAAGGCTTCCGCCTGTCGCCCGGTCTCGGC TGCACAGACGTGGATGAGTGCGCTGAGCCTGGGCTTAGCCACTGCCACGCCCTGGCCACATGTGTCAAT GTGGTGGGCAGCTACTTGTGCGTATGCCCCGCGGGCTACCGGGGGGATGGATGGCACTGTGAGTGCTCC CCGGGCTCCTGCGGGCCGGGGTTGGACTGCGTGCCCGAGGGCGACGCGCTCGTGTGCGCGGATCCGTGC CAGGCGCACCGCACCCTGGACGAGTACTGGCGCAGCACCGAGTACGGGGAGGGCTACGCCTGCGACACG GACCTGCGCGGCTGGTACCGCTTCGTGGGCCAGGGCGGTGCGCGCATGGCCGAGACCTGCGTGCCAGTC CTGCGCTGCAACACGGCCGCCCCCATGTGGCTCAATGGCACGCATCCGTCCAGCGACGAGGGCATCGTG AGCCGCAAGGCCTGCGCGCACTGGAGCGGCCACTGCTGCCTGTGGGATGCGTCCGTCCAGGTGAAGGCC TGTGCCGGCGGCTACTACGTCTACAACCTGACAGCGCCCCCCGAGTGTCACCTGGCGTACTGCACAGAC CCCAGCTCCGTGGAGGGGACGTGTGAGGAGTGCAGTATAGACGAGGACTGCAAATCGAATAATGGCAGA TGGCACTGCCAGTGCAAACAGGACTTCAACATCACTGATATCTCCCTCCTGGAGCACAGGCTGGAATGT GGGGCCAATGACATGAAGGTGTCGCTGGGCAAGTGCCAGCTGAAGAGTCTGGGCTTCGACAAGGTCTTC ATGTACCTGAGTGACAGCCGGTGCTCGGGCTTCAATGACAGAGACAACCGGGACTGGGTGTCTGTAGTG ACCCCAGCCCGGGATGGCCCCTGTGGGACAGTGTTGACGAGGAATGAAACCCATGCCACTTACAGCAAC ACCCTCTACCTGGCAGATGAGATCATCATCCGTGACCTCAACATCAAAATCAACTTTGCATGCTCCTAC CCCCTGGACATGAAAGTCAGCCTGAAGACCGCCCTACAGCCAATGGTCAGTGCTCTAAACATCAGAGTG GGCGGGACCGGCATGTTCACCGTGCGGATGGCGCTCTTCCAGACCCCTTCCTACACGCAGCCCTACCAA GGCTCCTCCGTGACACTGTCCACTGAGGCTTTTCTCTACGTGGGCACCATGTTGGATGGGGGCGACCTG TCCCGATTTGCACTGCTCATGACCAACTGCTATGCCACACCCAGTAGCAATGCCACGGACCCCCTGAAG TACTTCATCATCCAGGACAGATGCCCACACACTAGAGACTCAACTATCCAAGTGGTGGAGAATGGGGAG TCCTCCCAGGGCCGATTTTCCGTCCAGATGTTCCGGTTTGCTGGAAACTATGACCTAGTCTACCTGCAC TGTGAAGTCTATCTCTGTGACACCATGAATGAAAAGTGCAAGCCTACCTGCTCTGGGACCAGATTCCGA AGTGGGAGTGTCATAGATCAATCCCGTGTCCTGAACTTGGGTCCCATCACACGGAAAGGTGTCCAGGCC ACAGTCTCAAGGGCTTTTAGCAGCTTGGGGCTCCTGAAAGTCTGGCTGCCTCTGCTTCTCTCGGCCACC TTGACCCTGACTTTTCAG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239282
Blue=ORF Red=Cloning site Green=Tag(s) MGQPSLTWMLMVVVASWFITTAATDTSEARTKYNCPARWSWRTPQRGGDTEQGPDEDFTSQGRWCSECH SNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLG CTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDALVCADPC QAHRTLDEYWRSTEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIV SRKACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGR WHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVV TPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSALNIRV GGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLK YFIIQDRCPHTRDSTIQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFR SGSVIDQSRVLNLGPITRKGVQATVSRAFSSLGLLKVWLPLLLSATLTLTFQ TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001278614 |
| ORF Size | 2019 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001278614.2 |
| RefSeq Size | 2589 bp |
| RefSeq ORF | 2022 bp |
| Locus ID | 7369 |
| UniProt ID | P07911 |
| MW | 74 kDa |
| Gene Summary | The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
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