TGF alpha (TGFA) (NM_001099691) Human Tagged ORF Clone
CAT#: RG218141
- TrueORF®
TGFA (tGFP-tagged) - Human transforming growth factor, alpha (TGFA), transcript variant 2
ORF Plasmid: DDK
"NM_001099691" in other vectors (4)
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CNY 3,400.00
Cited in 1 publication. |
CNY 1,000.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | TFGA |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_001099691 |
ORF Size | 477 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001099691.3 |
RefSeq Size | 4261 bp |
RefSeq ORF | 480 bp |
Locus ID | 7039 |
UniProt ID | P01135 |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | ErbB signaling pathway, Glioma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Renal cell carcinoma |
Gene Summary | This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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The protein secretion modulator TMED9 drives CNIH4/TGFα/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases
,Mishra, S;Bernal, C;Silvano, M;Anand, S;Ruiz I Altaba, A;,
Oncogene
,PubMed ID 31253868
[TGFA]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC218141 | TGFA (Myc-DDK-tagged)-Human transforming growth factor, alpha (TGFA), transcript variant 2 |
CNY 1,800.00 |
|
RC218141L3 | Lenti ORF clone of Human transforming growth factor, alpha (TGFA), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC218141L4 | Lenti ORF clone of Human transforming growth factor, alpha (TGFA), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
SC316662 | TGFA (untagged)-Human transforming growth factor, alpha (TGFA), transcript variant 2 |
CNY 3,990.00 |
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