MRP2 (ABCC2) (NM_000392) Human Tagged Lenti ORF Clone
CAT#: RC218976L1
- LentiORF®
Lenti-ORF clone of ABCC2 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2)
"NM_000392" in other vectors (6)
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CNY 18,256.00
CNY 600.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | ABC30; CMOAT; cMRP; DJS; MRP2 |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218976).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_000392 |
ORF Size | 4635 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000392.1 |
RefSeq Size | 4868 bp |
RefSeq ORF | 4638 bp |
Locus ID | 1244 |
UniProt ID | Q92887 |
Domains | ABC_membrane, ABC_tran, AAA |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | ABC transporters |
MW | 174 kDa |
Gene Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC218976 | ABCC2 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2) |
CNY 15,856.00 |
|
RC218976L2 | Lenti-ORF clone of ABCC2 (mGFP-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2) |
CNY 7,600.00 |
|
RC218976L3 | Lenti-ORF clone of ABCC2 (Myc-DDK-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2) |
CNY 7,600.00 |
|
RC218976L4 | Lenti-ORF clone of ABCC2 (mGFP-tagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2) |
CNY 18,256.00 |
|
RG218976 | ABCC2 (tGFP-tagged) - Human ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2) |
CNY 17,456.00 |
|
SC119897 | ABCC2 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2) |
CNY 15,864.00 |