SOS1 (NM_005633) Human Tagged Lenti ORF Clone
CAT#: RC213531L1
- LentiORF®
Lenti ORF clone of Human son of sevenless homolog 1 (Drosophila) (SOS1), Myc-DDK-tagged
"NM_005633" in other vectors (6)
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CNY 16,320.00
CNY 600.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | GF1; GGF1; GINGF; HGF; NS4; SOS-1 |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC213531).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_005633 |
ORF Size | 3999 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_005633.2 |
RefSeq Size | 4002 bp |
RefSeq ORF | 4002 bp |
Locus ID | 6654 |
UniProt ID | Q07889 |
Domains | RhoGEF, RasGEFN, PH, RasGEF |
Protein Families | Druggable Genome |
Protein Pathways | Acute myeloid leukemia, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway |
MW | 152.3 kDa |
Gene Summary | This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC213531 | SOS1 (Myc-DDK-tagged)-Human son of sevenless homolog 1 (Drosophila) (SOS1) |
CNY 13,920.00 |
|
RC213531L2 | Lenti ORF clone of Human son of sevenless homolog 1 (Drosophila) (SOS1), mGFP tagged |
CNY 12,730.00 |
|
RC213531L3 | Lenti ORF clone of Human son of sevenless homolog 1 (Drosophila) (SOS1), Myc-DDK-tagged |
CNY 12,730.00 |
|
RC213531L4 | Lenti ORF clone of Human son of sevenless homolog 1 (Drosophila) (SOS1), mGFP tagged |
CNY 12,730.00 |
|
RG213531 | SOS1 (tGFP-tagged) - Human son of sevenless homolog 1 (Drosophila) (SOS1) |
CNY 15,520.00 |
|
SC116602 | SOS1 (untagged)-Human son of sevenless homolog 1 (Drosophila) (SOS1) |
CNY 13,688.00 |